Abstract: The present disclosure relates to a novel peptide derivative, etc., the peptide derivative being a partially modified adiponectin receptor peptide which, compared to conventional adiponectin receptor peptides, has higher stability, superior p-AMPK activity, and improved physical properties and activity and thus offers advantages when formulated into a drug. Therefore, the peptide derivative of the present invention can be used to prevent or treat inflammatory skin diseases, wounds, hair loss, fibrosis, metabolic diseases, or cancer, to prevent or alleviate aging, sensitive skin, or wrinkles, or to enhance moisturization.

Abstract: The present invention relates to a novel peptoid derivative and the like. The peptoid derivative is obtained by partially modifying an adiponectin receptor peptide, and has high stability and excellent p-AMPK activity, compared to existing adiponectin receptor peptides and has improved physical properties and activity, thus having the advantage of being suitable for drug formulation. Therefore, the peptoid derivative of the present invention can be used for the prevention or treatment of skin inflammatory diseases, wounds, hair loss, fibrosis, metabolic diseases, or cancer, or the prevention or amelioration of aging, sensitive skin, wrinkles, or moisturization.

Abstract: The present invention relates to a composition for an organic optoelectronic device, the composition comprising: a first host compound represented by Chemical Formula 1 below; and a second host compound represented by Chemical Formula 2 below, to an organic optoelectronic device using the composition and a display device. The details of Chemical Formulas 1 and 2 above are as defined in the specification.

Abstract: The present disclosure relates to separation and purification methods for a vaccine virus using affinity chromatography, and more particularly, to a purification method for a virus capable of obtaining a vaccine virus with a high purity and a high yield using affinity chromatography containing a vaccine virus-affinity resin.

Abstract: The present invention relates to a method for estimating a geothermal gradient and an apparatus for estimating a geothermal gradient, and provides a method for estimating a geothermal gradient, the method comprising the steps of: calculating, at each of a plurality of points, a seismic wave crustal attenuation characteristic parameter of a seismic wave measured on the basis of the measured seismic wave information, with respect to the plurality of points; deriving an artificial neural network relational formula on the basis of the seismic wave crustal attenuation characteristic parameter; and calculating a geothermal gradient of an area of interest excluding the plurality of points on the basis of the artificial neural network relational formula, such that the geothermal gradient is estimated at a low cost by using a highly reliable method.

Abstract: The present invention relates to a method for estimating a geothermal gradient and an apparatus for estimating a geothermal gradient, and provides a method for estimating a geothermal gradient, the method comprising the steps of: calculating, at each of a plurality of points, a seismic wave crustal attenuation characteristic parameter of a seismic wave measured on the basis of the measured seismic wave information, with respect to the plurality of points; deriving an artificial neural network relational formula on the basis of the seismic wave crustal attenuation characteristic parameter; and calculating a geothermal gradient of an area of interest excluding the plurality of points on the basis of the artificial neural network relational formula, such that the geothermal gradient is estimated at a low cost by using a highly reliable method.