Patents by Inventor Eun-Jung Son

Eun-Jung Son has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210138012
    Abstract: A method for or treating respiratory disease according to an embodiment includes administering to a subject in need thereof an extract of Siraitia grosvenorii residuals as an effective component. The extract of Siraitia grosvenorii residuals has, in an animal model having asthma induced by ovalbumin (OVA), an effect of reducing airway hyper-responsiveness, inhibiting inflammatory cells in bronchoalveolar lavage fluid (BALF), reducing Th2 cytokines (IL-4, IL-5, and IL-13) in BALF, reducing inflammation and tissue damage in lung tissues, inhibiting contraction of airway smooth muscle and airway inflammation, an effect of inhibiting expression of IL-13, TARC, TNF-?, IL-17, and MUC5AC, which is a gene encoding mucus protein, in lung tissues, an effect of reducing the level of ovalbumin-specific IgE in blood serum, and an effect of reducing ROS in alveolar cells which is generated in excess amount due to fine dust.
    Type: Application
    Filed: January 15, 2021
    Publication date: May 13, 2021
    Inventors: Dong Seon KIM, Yoon-Young SUNG, Yun Mi LEE, Eun Jung SON, Heung Joo YUK, Young-Sil LEE
  • Publication number: 20200268827
    Abstract: A method for treating osteoarthritis according to an embodiment of the present invention includes administering to a subject in need thereof a composition comprising an extract of Alpinia oxyphylla. The extract of Alpinia oxyphylla can reduce the expression of IL-1?, IL-6, TNF-? and COX-2 as an inflammatory factor and also the expression of MMP-9 as a cartilage degeneration-inducing factor, and can heal the cartilage damage, and thus it can be advantageously used as a functional health food composition for prevention or improvement of osteoarthritis or a therapeutic agent for osteoarthritis.
    Type: Application
    Filed: September 12, 2018
    Publication date: August 27, 2020
    Applicant: KOREA INSTITUTE OF ORIENTAL MEDICINE
    Inventors: Dong Seon KIM, Yun Mi LEE, Eun Jung SON, Ji Youn KIM
  • Patent number: 10709754
    Abstract: The present invention relates to a composition for preventing, ameliorating, or treating hyperuricemia or metabolic disorders related with hyperuricemia comprising an extract of Alpinia oxyphylla as an effective ingredient. Because the extract of Alpinia oxyphylla of the present invention can reduce the uric acid amount in blood of an animal model and is derived from natural products, and the raw materials can be easily obtained, it can be widely used in industries that are related to hyperuricemia or metabolic disorders related with hyperuricemia. It can be effectively used for prevention, amelioration, or treatment of gout or gouty arthritis, in particular.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: July 14, 2020
    Assignee: KOREA INSTITUTE OF ORIENTAL MEDICINE
    Inventors: Dong Seon Kim, Ohn Soon Kim, Yun Mi Lee, Young-Sil Lee, Eun Jung Son
  • Publication number: 20190099465
    Abstract: The present invention relates to a composition for preventing, ameliorating, or treating hyperuricemia or metabolic disorders related with hyperuricemia comprising an extract of Alpinia oxyphylla as an effective ingredient. Because the extract of Alpinia oxyphylla of the present invention can reduce the uric acid amount in blood of an animal model and is derived from natural products, and the raw materials can be easily obtained, it can be widely used in industries that are related to hyperuricemia or metabolic disorders related with hyperuricemia. It can be effectively used for prevention, amelioration, or treatment of gout or gouty arthritis, in particular.
    Type: Application
    Filed: April 7, 2017
    Publication date: April 4, 2019
    Inventors: Dong Seon KIM, Ohn Soon KIM, Yun Mi LEE, Young-Sil LEE, Eun Jung SON
  • Patent number: 8771761
    Abstract: The present invention relates to a composition comprising of plant extract as an active component, specifically, Bamboo extract and Scutellaria extract, for the treatment and prevention of atopic dermatitis. The present invention is a natural ingredient obtained from a plant. The present invention can control immune responses by inhibiting the release of histamine and leukotriene, and thus, has effect in the treatment or prevention of allergic diseases, inflammatory diseases and skin diseases, specifically atopic dermatitis. The present invention has been proven safe and beneficial effecting the treatment of atopic dermatitis through clinical trials, and thus, can be used for the treatment and prevention of atopic dermatitis.
    Type: Grant
    Filed: August 15, 2012
    Date of Patent: July 8, 2014
    Assignee: Unigen, Inc.
    Inventors: Sung Sick Woo, Dong Seon Kim, Young Chul Lee, Eun Jung Son
  • Patent number: 8586550
    Abstract: The present invention relates to a novel compound with thiazole ring having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney, and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes.
    Type: Grant
    Filed: June 10, 2011
    Date of Patent: November 19, 2013
    Assignee: Green Cross Corporation
    Inventors: Jinhwa Lee, Jeongmin Kim, Suk Ho Lee, Junwon Lee, Kwang-Seop Song, Eun-Jung Park, Min Ju Kim, Hee Jeong Seo, Sung-Han Lee, Eun Jung Son, Jong Yup Kim, Suk Youn Kang, Younggyu Kong
  • Patent number: 8541380
    Abstract: A novel C-aryl glucoside compound, or a pharmaceutically acceptable salt or a prodrug thereof having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney; and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly, diabetes, are provided.
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: September 24, 2013
    Assignee: Green Cross Corporation
    Inventors: Jinhwa Lee, Suk Ho Lee, Hee Jeong Seo, Min Ju Kim, Suk Youn Kang, Jeongmin Kim, Sung-Han Lee, Myung Eun Jung, Eun Jung Son, Kwang-Seop Song, Mi-Soon Kim
  • Publication number: 20130090298
    Abstract: The present invention relates to a novel compound with thiazole ring having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney, and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes.
    Type: Application
    Filed: June 10, 2011
    Publication date: April 11, 2013
    Applicant: GREEN CROSS CORPORATION
    Inventors: Jinhwa Lee, Jeongmin Kim, Suk Ho Lee, Junwon Lee, Kwang-Seop Song, Eun-Jung Park, Min Ju Kim, Hee Jeong Seo, Sung-Han Lee, Eun Jung Son, Jong Yup Kim, Suk Youn Kang, Younggyu Kong
  • Publication number: 20130064910
    Abstract: The present invention relates to a composition comprising of plant extract as an active component, specifically, Bamboo extract and Scutellaria extract, for the treatment and prevention of atopic dermatitis. The present invention is a natural ingredient obtained from a plant. The present invention can control immune responses by inhibiting the release of histamine and leukotrien, and thus, has effect in the treatment or prevention of allergic diseases, inflammatory diseases and skin diseases, specifically atopic dermatitis. The present invention has been proven safe and beneficial effecting the treatment of atopic dermatitis through clinical trials, and thus, can be used for the treatment and prevention of atopic dermatitis.
    Type: Application
    Filed: August 15, 2012
    Publication date: March 14, 2013
    Applicant: Unigen, Inc.
    Inventors: Sung Sick Woo, Dong Seon Kim, Young Chul Lee, Eun Jung Son
  • Patent number: 8247007
    Abstract: The present invention relates to a composition comprising of plant extract as an active component, specifically, Bamboo extract and Scutellaria extract, for the treatment and prevention of atopic dermatitis. The present invention is a natural ingredient obtained from a plant. The present invention can control immune responses by inhibiting the release of histamine and leukotrien, and thus, has effect in the treatment or prevention of allergic diseases, inflammatory diseases and skin diseases, specifically atopic dermatitis. The present invention has been proven safe and beneficial effecting the treatment of atopic dermatitis through clinical trials, and thus, can be used for the treatment and prevention of atopic dermatitis.
    Type: Grant
    Filed: October 12, 2007
    Date of Patent: August 21, 2012
    Assignee: Unigen, Inc.
    Inventors: Sung Sick Woo, Dong Seon Kim, Young Chul Lee, Eun Jung Son
  • Patent number: 8178551
    Abstract: The present invention is directed to a novel prodrug of (+)-3-hydroxymorphinan compound of formula (I) or a pharmaceutically acceptable salt thereof, a method for preparing the same, and its use for preventing or treating Parkinson's disease.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: May 15, 2012
    Assignee: Green Cross Corporation
    Inventors: Jinhwa Lee, Jeongmin Kim, Myung Eun Jung, Jong Yup Kim, Kwang-Seop Song, Eun Jung Son, Suk Ho Lee, Ho Kyun Han, Min Ju Kim, MinWoo Lee
  • Publication number: 20120101051
    Abstract: A novel C-aryl glucoside compound, or a pharmaceutically acceptable salt or a prodrug thereof having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney; and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly, diabetes, are provided.
    Type: Application
    Filed: June 18, 2010
    Publication date: April 26, 2012
    Applicant: GREEN CROSS CORPORATION
    Inventors: Jinhwa Lee, Suk Ho Lee, Hee Jeong Seo, Min Ju Kim, Suk Youn Kang, Jeongmin Kim, Sung-Han Lee, Myung Eun Jung, Eun Jung Son, Kwang-Seop Song, Mi-Soon Kim
  • Publication number: 20100113500
    Abstract: The present invention is directed to a novel prodrug of (+)-3-hydroxymorphinan compound of formula (I) or a pharmaceutically acceptable salt thereof, a method for preparing the same, and its use for preventing or treating Parkinson's disease.
    Type: Application
    Filed: March 7, 2008
    Publication date: May 6, 2010
    Applicant: GREEN CROSS CORPORATION
    Inventors: Jinhwa Lee, Jeongmin Kim, Myung Eun Jung, Jong Yup Kim, Kwang-Seop Song, Eun Jung Son, Suk Ho Lee, Ho Kyun Han, Min Ju Kim, MinWoo Lee
  • Publication number: 20100015257
    Abstract: The present invention relates to a composition comprising of plant extract as an active component, specifically, Bamboo extract and Scutellaria extract, for the treatment and prevention of atopic dermatitis. The present invention is a natural ingredient obtained from a plant. The present invention can control immune responses by inhibiting the release of histamine and leukotrien, and thus, has effect in the treatment or prevention of allergic diseases, inflammatory diseases and skin diseases, specifically atopic dermatitis. The present invention has been proven safe and beneficial effecting the treatement of atopic dermitatis through clinical trials, and thus, can be used for the treatment and prevention of atopic dermitatis.
    Type: Application
    Filed: October 12, 2007
    Publication date: January 21, 2010
    Applicant: UNIGEN, INC.
    Inventors: Sung Sick Woo, Dong Seon Kim, Young Chul Lee, Eun Jung Son
  • Publication number: 20080262066
    Abstract: A novel azole compound of formula (I) or a pharmaceutically acceptable salt thereof is effective as a cannabinoid CB1 receptor inverse agonist or antagonist, which is useful for preventing or treating obesity and obesity-related metabolic disorders. The prevention also provides a method for preparing same, a pharmaceutical composition containing same, and a method for preventing or treating obesity and obesity-related metabolic disorders.
    Type: Application
    Filed: April 18, 2008
    Publication date: October 23, 2008
    Applicant: Green Cross Corporation
    Inventors: Jinhwa LEE, Jeongmin Kim, Kwang-Seop Song, Min Ah Kim, Jong Yup Kim, Suk Ho Lee, Hee Jeong Seo, Sung-Han Lee, Myung Eun Jung, Kwang Woo Ahn, Eun Jung Son
  • Patent number: 6790937
    Abstract: The present invention relates to (a) variable regions of heavy and light chains of an antibody specific to a surface antigen in sporozoite of Eimeria spp.; (b) a recombinant scFV (single chain variable fragment) antibody prepared using the variable regions; (c) a method for preparing a recombinant scFv antibody; and (d) an expression vector for expressing a recombinant scFv antibody.
    Type: Grant
    Filed: February 26, 2002
    Date of Patent: September 14, 2004
    Assignee: Avicore Biotechnology Institute Inc.
    Inventors: Jin-Kyoo Kim, Jae-Yong Han, Ki-Duck Song, Sung-Won Kim, Won-Gi Min, Eun-Jung Son, Hyun Soon Lillehoj, Erik Peter Lillehoj
  • Publication number: 20030104497
    Abstract: The present invention relates to (a) variable regions of heavy and light chains of an antibody specific to a surface antigen in sporozoite of Eimeria spp.; (b) a recombinant scFV (single chain variable fragment) antibody prepared using the variable regions; (c) a method for preparing a recombinant scFv antibody; and (d) an expression vector for expressing a recombinant scFv antibody.
    Type: Application
    Filed: February 26, 2002
    Publication date: June 5, 2003
    Inventors: Jin-Kyoo Kim, Jae-Yong Han, Ki-Duck Song, Sung-Won Kim, Won-Gi Min, Eun-Jung Son, Hyun Soon Lillehoj, Erik Peter Lillehoj