Abstract: The present invention relates to an antigen-binding molecule comprising a heavy chain variable region comprising a heavy-chain complementarity-determining region 1 (HCDR1) comprising an amino acid sequence represented by Sequence No. 1, an HCDR2 comprising an amino acid sequence represented by Sequence No. 2, and an HCDR3 comprising an amino acid sequence represented by Sequence No. 3; a light-chain variable region comprising a light-chain complementarity-determining region 1 (LCDR1) comprising an amino acid sequence represented by Sequence No. 4, an LCDR2 comprising an amino acid sequence represented by Sequence No. 5, and an LCDR3 comprising an amino acid sequence represented by Sequence No. 6; wherein the antigen-binding molecule is a T cell receptor (TCR); and to a cell line expressing the same.

Abstract: The invention provides methods and systems for detecting a biomarker in a synovial fluid wherein the system also includes a control to ensure that the test sample is indeed synovial fluid. The biomarkers and the control for synovial fluid can be identified using proteomic methods, including but not limited to antibody based methods, such as an enzyme-linked immunosorbant assay (ELISA), a radioimmunoassay (RIA), or a lateral flow immunoassay.

Abstract: The invention provides methods and systems for detecting a biomarker in a synovial fluid wherein the system also includes a control to ensure that the test sample is indeed synovial fluid. The biomarkers and the control for synovial fluid can be identified using proteomic methods, including but not limited to antibody based methods, such as an enzyme-linked immunosorbant assay (ELISA), a radioimmunoassay (RIA), or a lateral flow immunoassay.

Abstract: Provided are a method and a composition for preventing or treating atopic dermatitis through administration of monoclonal stem cells and a method for screening atopic dermatitis patients suitable for administration of monoclonal stem cells and predicting prognosis of patients. According to the method for the subfractionation culture and proliferation of stem cells of the disclosure, large quantities of desired monoclonal mesenchymal stem cells can be obtained in a short period of time through rapid proliferation of monoclonal mesenchymal stem cells. In addition, the monoclonal mesenchymal stem cells thus obtained can be administered to atopic dermatitis patients according to a prescribed administration cycle, guidelines, and dose to effectively ameliorate atopy symptoms in the patients.

Abstract: The invention provides methods and systems for detecting a biomarker in a synovial fluid wherein the system also includes a control to ensure that the test sample is indeed synovial fluid. The biomarkers and the control for synovial fluid can be identified using proteomic methods, including but not limited to antibody based methods, such as an enzyme-linked immunosorbant assay (ELISA), a radioimmunoassay (RIA), or a lateral flow immunoassay.

Abstract: The invention provides methods and systems for detecting a biomarker in a synovial fluid wherein the system also includes a control to ensure that the test sample is indeed synovial fluid. The biomarkers and the control for synovial fluid can be identified using proteomic methods, including but not limited to antibody based methods, such as an enzyme-linked immunosorbant assay (ELISA), a radioimmunoassay (RIA), or a lateral flow immunoassay.

Abstract: The invention provides methods and systems for detecting a biomarker in a synovial fluid wherein the system also includes a control to ensure that the test sample is indeed synovial fluid. The biomarkers and the control for synovial fluid can be identified using proteomic methods, including but not limited to antibody based methods, such as an enzyme-linked immunosorbant assay (ELISA), a radioimmunoassay (RIA), or a lateral flow immunoassay.

Abstract: A novel technique automatically stores synchronized group history related to an online group interaction and enables individual group members to later view and access the group history. In an embodiment of the invention, the group history is accessible by group members independently of group interactions at any later time. According to various embodiments of the invention, the group history may be presented in an overview form or a detailed form. With respect to the detailed form, the group history may be presented graphically, such as in an icon timeline or collage, textually, such as in list form, or in any combination of presentation formats. In a further embodiment of the invention, the synchronized group history is writable by group members in addition to being automatically maintained.

Abstract: Attachment browser is described. In an embodiment, an attachment browser displays a selection of communications received from multiple sources where each of the communications has an attachment. A representative image of each attachment is organized for display according to an attribute of the respective attachment, and a portion of each communication is displayed proximate an associated representative image to maintain the association of a communication and a respective attachment.

Abstract: Techniques for enabling mobile shared group interaction are described. Members of a group may access, through a user interface, group activities that provide a shared, synchronous, interactive experience. An interface may be provided via a mobile device such as a cellular telephone that enables members who are mobile to participate in group activities with other members who are also mobile or who are logged on via a non-mobile device such as a desktop computer system.

Abstract: Bubble messaging may include creating a bubble message and seamlessly sending the bubble message to one or more recipients. The bubble message may include message text and a bubble message shape specification. As a result of the bubble message being sent, a notification of the bubble message may be received. The notification of the bubble message may be displayed and, in response to recipient interaction with the displayed notification, a bubble message open animation may be displayed that provides a transition to a shape specified by the bubble message shape specification. The bubble message may be displayed with the shape specified by the bubble message shape specification. A bubble message editor may be configured to enable the creation and seamless sending of the bubble message. A bubble message viewer may be configured to enable the display of bubble messages. The bubble message may be unmodifiable after creation.

Abstract: A novel technique enables participants of an online group interaction to capture and encapsulate an ongoing activity at a particular moment in time. During the online group interaction, a user activates an icon, and is enabled to select properties of the saved memory, such as icon color/image for the saved material, what parts of the shared experience to save, etc. For example, the user may want to save all or some of the conversation, music played, scores for a game played, and the pictures viewed during the session, as well as any other portion desired. The saved material may represent a snapshot of the activity at save time, or may comprise a sequence of events up to the point that the material was saved. While saving the selected material, the application displays an animation such as an origami-type animation of a box folding up from a flat sheet.

Abstract: A novel virtual calling card system and method aid in the formation of online relationships, serving as an introduction tool and as a contact mechanism. The calling card is an exchangeable entity that is automatically updated, ensuring that the recipient or viewer sees the most current version of the card. The card may display an aspect ratio that is the same as that of a traditional business card, and has front side and a reverse side. Furthermore, the card provides a number of avenues for the card owner to express themselves, including an array of affiliation symbols, a most recent mood symbol, and a text field. The reverse side of the card can display a representation of the owner's social network, so that recipients of the card may identify common friends and associates. Thus, the server-based card exchange appears to users as an exchange in the physical world.

Abstract: A novel virtual calling card system and method aid in the formation of online relationships, serving as an introduction tool and as a contact mechanism. The calling card is an exchangeable entity that is automatically updated, ensuring that the recipient or viewer sees the most current version of the card. The card may display an aspect ratio that is the same as that of a traditional business card, and has a front side and a reverse side. Furthermore, the card provides a number of avenues for the card owner to express themselves, including an array of affiliation symbols, a most recent mood symbol, and a text field. The reverse side of the card can display a representation of the owner's social network, so that the recipients of the card may identify common friends and associates. Thus, the sewer-based card exchange appears to users as an exchange in the physical world.

Abstract: A novel virtual calling card system and method aid in the formation of online relationships, serving as an introduction tool and as a contact mechanism. The calling card is an exchangeable entity that is automatically updated, ensuring that the recipient or viewer sees the most current version of the card. The card may display an aspect ratio that is the same as that of a traditional business card, and has a front side and a reverse side. Furthermore, the card provides a number of avenues for the card owner to express themselves, including an array of affiliation symbols, a most recent mood symbol, and a text field. The reverse side of the card can display a representation of the owner's social network, so that the recipients of the card may identify common friends and associates. Thus, the server-based card exchange appears to users as an exchange in the physical world.

Abstract: A novel virtual calling card system and method aid in the formation of online relationships, serving as an introduction tool and as a contact mechanism. The calling card is an exchangeable entity that is automatically updated, ensuring that the recipient or viewer sees the most current version of the card. The card may display an aspect ratio that is the same as that of a traditional business card, and has front side and a reverse side. Furthermore, the card provides a number of avenues for the card owner to express themselves, including an array of affiliation symbols, a most recent mood symbol, and a text field. The reverse side of the card can display a representation of the owner's social network, so that recipients of the card may identify common friends and associates. The exchange of the card, although server-based, appears to users to simply be a transfer of the card from the owner, or other party, to the recipient, much as a card changes hands in the physical world.

Abstract: A novel virtual calling card system and method aid in the formation of online relationships, serving as an introduction tool and as a contact mechanism. The calling card is an exchangeable entity that is automatically updated, ensuring that the recipient or viewer sees the most current version of the card. The card may display an aspect ratio that is the same as that of a traditional business card, and has front side and a reverse side. Furthermore, the card provides a number of avenues for the card owner to express themselves, including an array of affiliation symbols, a most recent mood symbol, and a text field. The reverse side of the card can display a representation of the owner's social network, so that recipients of the card may identify common friends and associates. The exchange of the card, although server-based, appears to users to simply be a transfer of the card from the owner, or other party, to the recipient, much as a card changes hands in the physical world.

Abstract: Attachment browser is described. In an embodiment, an attachment browser displays a selection of communications received from multiple sources where each of the communications has an attachment. A representative image of each attachment is organized for display according to an attribute of the respective attachment, and a portion of each communication is displayed proximate an associated representative image to maintain the association of a communication and a respective attachment.

Abstract: Bubble messaging may include creating a bubble message and seamlessly sending the bubble message to one or more recipients. The bubble message may include message text and a bubble message shape specification. As a result of the bubble message being sent, a notification of the bubble message may be received. The notification of the bubble message may be displayed and, in response to recipient interaction with the displayed notification, a bubble message open animation may be displayed that provides a transition to a shape specified by the bubble message shape specification. The bubble message may be displayed with the shape specified by the bubble message shape specification. A bubble message editor may be configured to enable the creation and seamless sending of the bubble message. A bubble message viewer may be configured to enable the display of bubble messages. The bubble message may be unmodifiable after creation.

Abstract: Techniques for enabling mobile shared group interaction are described. Members of a group may access, through a user interface, group activities that provide a shared, synchronous, interactive experience. An interface may be provided via a mobile device such as a cellular telephone that enables members who are mobile to participate in group activities with other members who are also mobile or who are logged on via a non-mobile device such as a desktop computer system.