Abstract: A composition for strengthening, developing, differentiating, or regenerating muscle, or preventing, ameliorating, or treating muscle loss or muscle fatigue includes a Schizonepeta tenuifolia extract as an effective component. The Schizonepeta tenuifolia extract as an effective component has the effects of restoring the viability of muscle cells, increasing the endurance time on the rotarod performance test, i.e., the holding time without falling off from the rod, compared to the control group, reducing the content of LDH, AST, and ALT in blood, increasing the grip strength, enhancing the expression amount of energy metabolism-related genes in muscle tissues, increasing the density of muscle fibers in muscle tissues, inducing a change in the fibroblast arrangement to have a well-organized structure, and reducing the expression of MuRF1 in muscle tissues, as compared to the control group.

Abstract: A quantum dot including a core that includes a first semiconductor nanocrystal including zinc and selenium, and optionally sulfur and/or tellurium, and a shell that includes a second semiconductor nanocrystal including zinc, and at least one of sulfur or selenium is disclosed. The quantum dot has an average particle diameter of greater than or equal to about 13 nm, an emission peak wavelength in a range of about 440 nm to about 470 nm, and a full width at half maximum (FWHM) of an emission wavelength of less than about 25 nm. A method for preparing the quantum dot, a quantum dot-polymer composite including the quantum dot, and an electronic device including the quantum dot is also disclosed.

Abstract: Provided a gas diffusion layer for fuel cells, the gas diffusion layer including: a carbon substrate; and a microporous layer formed on the carbon substrate, wherein the microporous layer comprises first carbon particles having a partially graphitized structure and a water-repellent binder resin binding the first carbon particles, and the microporous layer further comprises a cerium compound, a nitrogen-doped cerium compound, nitrogen-doped second carbon particles having a partially graphitized or non-graphitized structure, or a mixture of two or more, as a radical scavenger capable of removing hydrogen peroxide generated at a fuel cell open circuit potential or a higher potential.

Abstract: The present invention relates to a method for isolation of autologous cancer antigen-specific CD8 T cell by using CD71 and uses thereof. In case of isolating autologous cancer antigen-reactive CD8 T cells using the isolation method of the present invention, it is possible to provide significant anticancer effects by amplifying a large amount of CD8 T cells even with less blood since CD8 T cells responding to various cancer antigens in addition to CD8 T cells specific for autologous cancer antigen are also separated. Therefore, it can be effectively used for immunotherapy that induces temporary immunodeficiency for treatment such as adoptive cell therapy.

Abstract: Provided is a method for treating or preventing cancer, containing, as an active ingredient, a compound having a specific chemical structure and an activity of inhibiting the formation of a c-Myc/Max/DNA complex, or a pharmaceutically acceptable salt thereof.

Abstract: Provided a gas diffusion layer for fuel cells, the gas diffusion layer including: a carbon substrate; and a microporous layer formed on the carbon substrate, wherein the microporous layer comprises first carbon particles having a partially graphitized structure and a water-repellent binder resin binding the first carbon particles, and the microporous layer further comprises a cerium compound, a nitrogen-doped cerium compound, nitrogen-doped second carbon particles having a partially graphitized or non-graphitized structure, or a mixture of two or more, as a radical scavenger capable of removing hydrogen peroxide generated at a fuel cell open circuit potential or a higher potential.

Abstract: Provided is a gas diffusion layer, in which a microporous layer has an inner wall of through passages and a region adjacent to the through passages containing a greater amount of a water-repellent binder resin than a region not adjacent to the through passages, and thus water formed by an electrochemical reaction is effectively discharged from the gas diffusion layer. When the gas diffusion layer of the present invention is used, an optimal water management may be possible for smooth operation under all humidity conditions including a high humidity condition and a low humidity condition, and thus a fuel cell having improved cell performance may be obtained.

Abstract: Disclosed is a structure for detecting cell-free DNA using a conductive polymer and the use thereof. More particularly, a nanostructure composed of a surface-modified conductive polymer for isolating and detecting cell-free DNA is disclosed. By using the nanostructure, cell-free DNA including circulating tumor DNA, can be effectively detected and isolated.

Abstract: A novel Lactobacillus paracasei AO356 strain according to the present disclosure, which is a strain isolated from the human body, has high stability, exhibits the activity of inhibiting adipogenic differentiation in vitro and inducing the differentiation of M1 and M0 macrophages into M2 macrophages, and has excellent activity of alleviating, preventing, or treating obesity, such as the activity of reducing body weight and a reduction in blood lipid concentration through the browning of white fat in animal experiments. Thus, the novel strain of the present disclosure has a low possibility of causing side effects, and therefore, unlike conventional diet functional foods or drugs, which have side effect problems, a diet effect can be exhibited without controlling the dose thereof. Accordingly, the novel strain can be used as a pharmaceutical composition for treating or preventing obesity or a food composition for alleviating or preventing obesity.

Abstract: A carbon substrate for a gas diffusion layer of a fuel cell, the carbon substrate being a porous carbon substrate having a first surface and a second surface opposite the first surface, the carbon substrate includes a plurality of carbon fibers arranged irregularly to form a non-woven type and a carbide of an organic polymer located between the carbon fibers to bind the carbon fibers to each other, the carbide has a graphite structure, and the carbon substrate has a Bragg diffraction angle 2? of less than 26.435° and a interplanar distance d(002) of less than 3.372 ?, a gas diffusion layer employing the same, an electrode for a fuel cell, a membrane electrode assembly for a fuel cell, and a fuel cell. When the gas diffusion layer is manufactured using the carbon substrate according to the present disclosure, cell voltage characteristics of the fuel cell may be greatly improved.

Abstract: The present invention relates to a pharmaceutical composition for preventing, treating or alleviating cancer, containing a PLK1 inhibitor as an active ingredient, and a compound according to the present invention selectively binds to PBD of PLK1, thereby having advantages of high selectivity and binding affinity for PLK1 and low toxicity. Therefore, a PLK inhibitor compound according to the present invention can be effectively used as an anticancer agent by inhibiting the growth of various cancer cells, and can be expected to exhibit synergistic effects with existing developed anticancer agents through co-administration, in addition to individual administration thereof.

Abstract: Disclosed are a carbon substrate for a gas diffusion layer of a fuel cell, a gas diffusion layer employing the same, an electrode for a fuel cell, a membrane electrode assembly for a fuel cell, and a fuel cell, wherein the carbon substrate includes a plate-shaped substrate having an upper surface and a lower surface opposite the upper surface, and the plate-shaped substrate includes carbon fibers arranged to extend in one direction (extend unidirectionally) and a carbide of an organic polymer located between the carbon fibers to bind the carbon fibers to each other.

Abstract: A novel Lactobacillus paracasei AO356 strain according to the present disclosure, which is a strain isolated from the human body, has high stability, exhibits the activity of inhibiting adipogenic differentiation in vitro and inducing the differentiation of M1 and M0 macrophages into M2 macrophages, and has excellent activity of alleviating, preventing, or treating obesity, such as the activity of reducing body weight and a reduction in blood lipid concentration through the browning of white fat in animal experiments. Thus, the novel strain of the present disclosure has a low possibility of causing side effects, and therefore, unlike conventional diet functional foods or drugs, which have side effect problems, a diet effect can be exhibited without controlling the dose thereof. Accordingly, the novel strain can be used as a pharmaceutical composition for treating or preventing obesity or a food composition for alleviating or preventing obesity.

Abstract: Provided is a method for treating or preventing cancer, containing, as an active ingredient, a compound having a specific chemical structure and an activity of inhibiting the formation of a c-Myc/Max/DNA complex, or a pharmaceutically acceptable salt thereof.

Abstract: Provided is a magnetic nanostructure for detecting and isolating cell-free DNA (cfDNA) that including a cationic polymer and a magnetic-nanoparticle-containing conductive polymer. The magnetic nanostructure for detecting and isolating cfDNA according to the subject matter can significantly improve detection and extraction efficiencies of DNA present in a urine, CSF, blood plasma, or blood sample, and exhibits an enhanced sensitivity. Therefore, it is expected that the magnetic nanostructure for detecting and isolating cfDNA according to the subject matter will be used for extracting DNA for use in a genetic mutation diagnosis service as well as for an early cancer diagnosis and cancer treatment.

Abstract: Disclosed is a structure for detecting cell-free DNA using a conductive polymer and the use thereof. More particularly, a nanostructure composed of a surface-modified conductive polymer for isolating and detecting cell-free DNA is disclosed. By using the nanostructure, cell-free DNA including circulating tumor DNA, etc. can be effectively detected and isolated.

Abstract: Disclosed are novel compounds of specific chemical structures having inhibitory activity on c-Myc/Max/DNA complex formation or pharmaceutically acceptable salts thereof.

Abstract: The present invention provides an apparatus for screening cancer, which reads low-mass ion mass spectrum for diagnosing cancer based on biostatistical analysis with respect to low-mass ions extracted from biological materials, and diagnoses cancer using the low-mass ion spectrum. An apparatus for cancer diagnosis, including a low-mass ion detecting unit which detects mass spectra of low-mass ions of biological materials; a cancer diagnosing unit which compares and analyzes patterns of mass spectra and diagnoses cancer; a display unit which displays cancer diagnosis information from the cancer diagnosing unit.

Abstract: Disclosed are novel compounds of specific chemical structures having inhibitory activity on c-Myc/Max/DNA complex formation or pharmaceutically acceptable salts thereof.

Abstract: Provided is a magnetic nanostructure for detecting and isolating cell-free DNA (cfDNA) that including a cationic polymer and a magnetic-nanoparticle-containing conductive polymer. The magnetic nanostructure for detecting and isolating cfDNA according to the subject matter can significantly improve detection and extraction efficiencies of DNA present in a urine, CSF, blood plasma, or blood sample, and exhibits an enhanced sensitivity. Therefore, it is expected that the magnetic nanostructure for detecting and isolating cfDNA according to the subject matter will be used for extracting DNA for use in a genetic mutation diagnosis service as well as for an early cancer diagnosis and cancer treatment.