Abstract: According to an embodiment, a medicine injection device comprises a medicine storage unit receiving a medicine cartridge storing a medicine, a needle unit connected with the medicine cartridge and injecting the medicine to a user, a driver configured to apply an external force to the medicine storage unit, a temperature sensor measuring a temperature of at least one of the medicine storage unit, the needle unit, the driver, and an outside of the medicine injection device, and a controller determining a medicine state indicating whether the medicine deteriorates based on the temperature measured by the temperature sensor and controlling the driver according to the determined medicine state to thereby determine whether to block the injection of the medicine.