Abstract: Disclosed is a novel dicarboxylic acid salt of sibutramine, which has good physicochemical properties. Also disclosed are a method of preparing the compound and a pharmaceutical composition comprising the compound.

Abstract: Disclosed is a novel sulphonic acid salt of sibutramine, which has good physicochemical properties. Also disclosed are a method of preparing the compound and a pharmaceutical composition comprising the compound.

Abstract: Disclosed are novel inorganic acid salts of sibutramine, which have good physicochemical properties, and crystalline forms thereof. Also disclosed are pharmaceutical compositions comprising the compounds as effective ingredients, methods of preparing the compounds, and the use of the compounds.

Abstract: Provided is a sustained-release formulation: (a) a sustained-release core including an active ingredient and a polymer having erosion and swelling property in mammalian intestinal secretions, (b) an enteric film coating layer coated on the sustained-release core, and (c) an active ingredient-containing film coating layer coated on the enteric film coating layer and including the active ingredient and hydrophilic polymer for film coating.

Abstract: There is provided a method of processing an ultrasound spectrum image. According to such method, a spectrum image is formed based on ultrasound data and then the noise is removed from the spectrum image. The noise-removed spectrum image is matched with one or more spectrum models representing specific spectrum types. Then, whether or not the noise-removed spectrum image contains an aliasing is checked. If the noise-removed spectrum image contains the aliasing, then the aliasing is removed from the noise-removed spectrum image to provide a noise-removed spectrum image without the aliasing. Thereafter, contour tracing is performed on the noise-removed spectrum image without the aliasing to detect contour points. Further, peak tracing is performed on the noise-removed spectrum image without the aliasing to detect peaks.

Abstract: The present invention relates to a method of improving a 3D ultrasound color Doppler image through a post-processing. A method of processing an ultrasound image, includes the following steps: a) recognizing a target object from an inputted ultrasound image based on an object recognition algorithm using connectivity of the target object; b) setting at least one object region by using the connectivity of the recognized target object; c) calculating a structure matrix by using voxel gradients of the object region; d) calculating a diffusion matrix from the structure matrix; and e) acquiring a processed ultrasound image by applying the diffusion matrix and the voxel gradients to the inputted ultrasound image.

Abstract: The present invention relates a method and an apparatus for enhancing ultrasound image quality through a post-processing. A method for enhancing an image quality of a two-dimensional (2D) ultrasound image, comprises the steps of: a) decomposing the 2D ultrasound image into a plurality of images having a multi-resolution by N levels, wherein N is a positive integer; b) determining characteristics of each pixel in the decomposed image; c) performing an enhancement process for the decomposed image based on the pixel characteristics; d) performing 1st-level composition for the decomposed image; and e) repeatedly performing steps b) to d) until a size of the composed image is identical to that of the 2D ultrasound image.