Patents by Inventor Eung-Ji LEE

Eung-Ji LEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240092829
    Abstract: The present application relates to a peptide having protective activity against cell damage caused by particulate matter, and to uses for the peptide.
    Type: Application
    Filed: November 26, 2020
    Publication date: March 21, 2024
    Inventors: Yong Ji CHUNG, Eun Mi KIM, Eung Ji LEE, Han A KANG, Bo Byeol HWANG
  • Publication number: 20240051993
    Abstract: The present invention relates to a peptide that specifically recognizes a protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or a portion thereof; a composition for preventing or treating SARS-CoV-2 infection, comprising the peptide; and a composition for detecting SARS-CoV-2, comprising the peptide.
    Type: Application
    Filed: July 15, 2021
    Publication date: February 15, 2024
    Applicant: CAREGEN CO, LTD.
    Inventors: Yong Ji CHUNG, Eun Mi KIM, Eung Ji LEE, Young Min LEE, Han A KANG, Min Kyeong JEONG
  • Publication number: 20240002439
    Abstract: The present application relates to a peptide having protective activity against cell damage caused by particulate matter, and to uses for the peptide.
    Type: Application
    Filed: November 26, 2020
    Publication date: January 4, 2024
    Inventors: Yong Ji CHUNG, Eun Mi KIM, Eung Ji LEE, Han A KANG, Bo Byeol HWANG
  • Patent number: 11859016
    Abstract: Provided are a peptide with a cytoprotective effect against environmental pollutants and a use thereof. The peptide consisting of an amino acid sequence of SEQ ID NO: 1, 2, or 3 directly binds to 2,3,7,8-tetrachlorodibenzo-p-dioxin (hereinafter, referred to as TCDD), known as being the most toxic among the class of dioxins, to prevent dermal penetration and the activation mechanism of AhR by TCDD and polycyclic aromatic hydrocarbons contained in fine dust. Such a direct cytoprotective effect against environmental pollutants is distinguished from preexisting methods that are configured to indirectly block opportunities to contact these materials or to reduce toxicity through barrier reinforcement.
    Type: Grant
    Filed: January 24, 2023
    Date of Patent: January 2, 2024
    Assignee: CAREGEN CO., LTD.
    Inventors: Yong Ji Chung, Eun Mi Kim, Eung-ji Lee
  • Publication number: 20230285263
    Abstract: The present disclosure relates to a peptide consisting of an amino acid sequence of SEQ ID NO: 1, 2, 3, or 4, a pharmaceutical composition for preventing or treating skin disease including the peptide, a cosmetic composition for skin condition improvement including the peptide, a food composition for skin condition improvement including the peptide, a method of preventing or treating skin disease using the peptide, and a use of the peptide in preventing or treating skin disease or improving skin condition.
    Type: Application
    Filed: April 28, 2023
    Publication date: September 14, 2023
    Inventors: Yong Ji CHUNG, Eun Mi KIM, Eung Ji LEE
  • Publication number: 20230285264
    Abstract: The present disclosure relates to a peptide consisting of an amino acid sequence of SEQ ID NO: 1, 2, 3, or 4, a pharmaceutical composition for preventing or treating skin disease including the peptide, a cosmetic composition for skin condition improvement including the peptide, a food composition for skin condition improvement including the peptide, a method of preventing or treating skin disease using the peptide, and a use of the peptide in preventing or treating skin disease or improving skin condition.
    Type: Application
    Filed: April 28, 2023
    Publication date: September 14, 2023
    Inventors: Yong Ji CHUNG, Eun Mi KIM, Eung Ji LEE
  • Publication number: 20230227501
    Abstract: Provided are a peptide with a cytoprotective effect against environmental pollutants and a use thereof. The peptide consisting of an amino acid sequence of SEQ ID NO: 1, 2, or 3 directly binds to 2,3,7,8-tetrachlorodibenzo-p-dioxin (hereinafter, referred to as TCDD), known as being the most toxic among the class of dioxins, to prevent dermal penetration and the activation mechanism of AhR by TCDD and polycyclic aromatic hydrocarbons contained in fine dust. Such a direct cytoprotective effect against environmental pollutants is distinguished from preexisting methods that are configured to indirectly block opportunities to contact these materials or to reduce toxicity through barrier reinforcement.
    Type: Application
    Filed: January 24, 2023
    Publication date: July 20, 2023
    Inventors: Yong Ji CHUNG, Eun Mi KIM, Eung-ji LEE
  • Publication number: 20230218498
    Abstract: The present invention related to the use of a composition comprising a pentapeptide as an active ingredient to suppress excessive sweating, to suppress body odor or to prevent or treat pain.
    Type: Application
    Filed: June 11, 2021
    Publication date: July 13, 2023
    Applicant: CAREGEN CO, LTD.
    Inventors: Yong Ji CHUNG, Eun Mi KIM, Eung Ji LEE
  • Publication number: 20230181441
    Abstract: The present invention relates to a Trolox-peptide conjugate having a structure in which Trolox and a peptide are chemically bonded. The Trolox-peptide conjugate not only very effectively inhibits the activity of 5?-reductase, but also inhibits the death of papilla cells and keratinocytes, promotes the growth thereof, and has antioxidative effects, and thus can remarkably promote hair formation while avoiding or preventing hair loss.
    Type: Application
    Filed: May 6, 2020
    Publication date: June 15, 2023
    Applicant: Caregen Co., Ltd.
    Inventors: Yong Ji CHUNG, Eun Mi KIM, Eung Ji LEE, Min Woong KIM
  • Patent number: 11672749
    Abstract: A peptide consisting of an amino acid sequence of SEQ ID NO: 1, 2, 3, or 4, a pharmaceutical composition for preventing or treating skin disease including the peptide, a cosmetic composition for skin condition improvement including the peptide, a food composition for skin condition improvement including the peptide, a method of preventing or treating skin disease using the peptide, and a use of the peptide in preventing or treating skin disease or improving skin condition are described.
    Type: Grant
    Filed: July 30, 2021
    Date of Patent: June 13, 2023
    Assignee: CAREGEN CO., LTD.
    Inventors: Yong Ji Chung, Eun Mi Kim, Eung Ji Lee
  • Patent number: 11654097
    Abstract: Provided are a peptide having skin-whitening activity and use thereof, and a peptide consisting of an amino acid sequence of SEQ ID NO: 1, SEQ ID NO: 2, or SEQ ID NO: 3, a skin-whitening composition including the peptide, a cosmetic composition including the skin-whitening composition, and a pharmaceutical composition for preventing or treating a melanin hyperpigmentation disease, the pharmaceutical composition including the skin-whitening composition.
    Type: Grant
    Filed: October 10, 2019
    Date of Patent: May 23, 2023
    Assignee: CAREGEN CO., LTD.
    Inventors: Yongji Chung, Eun Mi Kim, Eung Ji Lee, Jan Di Kim
  • Patent number: 11597748
    Abstract: Provided are a peptide with a cytoprotective effect against environmental pollutants and a use thereof. The peptide consisting of an amino acid sequence of SEQ ID NO: 1, 2, or 3 directly binds to 2,3,7,8-tetrachlorodibenzo-p-dioxin (hereinafter, referred to as TCDD), known as being the most toxic among the class of dioxins, to prevent dermal penetration and the activation mechanism of AhR by TCDD and polycyclic aromatic hydrocarbons contained in fine dust. Such a direct cytoprotective effect against environmental pollutants is distinguished from preexisting methods that are configured to indirectly block opportunities to contact these materials or to reduce toxicity through barrier reinforcement.
    Type: Grant
    Filed: August 2, 2021
    Date of Patent: March 7, 2023
    Assignee: CAREGEN CO., LTD.
    Inventors: Yong Ji Chung, Eun Mi Kim, Eung-ji Lee
  • Patent number: 11518785
    Abstract: The present invention provides a peptide exhibiting melanogenesis promoting activity. A peptide according to the present invention increases the activity and expression of tyrosinase and the expression of factors involved in melanogenesis, thereby exhibiting an outstanding effect on melanogenesis. The peptide of the present invention can be used for the prevention, alleviation, and treatment of hypomelanosis. The outstanding activity and stability stated above allow the peptide of the present invention to be very favorably applied to medicines, quasi-medicines, and cosmetics.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: December 6, 2022
    Assignee: CAREGEN CO., LTD.
    Inventors: Yong Ji Chung, Eun Mi Kim, Eung-Ji Lee
  • Patent number: 11512112
    Abstract: The peptide of the present invention performs a function, which is the same as or similar to that of natural interleukin (IL)-3, and has superior skin permeability due to the small size thereof. In addition, the peptide of the present invention suppresses the activation of NF-?B and nuclear transition by inhibiting the receptor activator of nuclear factor kappa-B ligand (RANKL)-RANK signaling pathway, and suppresses the expression of a RANKL or an inflammatory cytokine-induced tartrate-resistant acid phosphatase (TRAP), cathepsin K, or TNF receptor type 1 or type 2, thereby inhibiting osteoclast differentiation depending on the treatment concentration. Moreover, the peptide of the present invention can contribute to osteoblast differentiation by promoting the expression of osteoblast differentiation markers such as osteocalcin (OCN), osteoprotegerin (OPG), bone sialoprotein (BSP), or osteopontin (OPN).
    Type: Grant
    Filed: April 21, 2020
    Date of Patent: November 29, 2022
    Assignee: CAREGEN CO., LTD.
    Inventors: Yong Ji Chung, Eun-Mi Kim, Eung-Ji Lee, Tae-Hoon Lee, A-reum Han
  • Patent number: 11453700
    Abstract: Provided are a peptide having skin-whitening activity and use thereof, and a peptide composed of an amino acid sequence of SEQ ID NO: 1, a skin-whitening cosmetic composition including the peptide, a pharmaceutical composition for preventing or treating a hyperpigmentation disease, the pharmaceutical composition including the peptide, and a method of whitening the skin using the same, or a method of preventing, improving or treating a hyperpigmentation disease using the same.
    Type: Grant
    Filed: October 10, 2019
    Date of Patent: September 27, 2022
    Assignee: CAREGEN CO., LTD.
    Inventors: Yongji Chung, Eun Mi Kim, Eung Ji Lee
  • Patent number: 11433013
    Abstract: The present invention relates to: a novel peptide having activity of preventing skin damage caused by pollutants, and skin anti-aging and wrinkle alleviation activities; and a use of the peptide, which is related to the prevention or treatment of diseases caused by pollutants or to the improvement of skin anti-aging. Particularly, the novel peptide of the present invention inhibits the inflow, into skin cells, of pollutants such as dioxin, particulate matter, and cigarette smoke, and regulates the expression of a skin aging-related gene, and thus may be effectively used as an active ingredient of a pharmaceutical composition for preventing or treating cancer, skin diseases, and lung diseases, which are caused by pollutants, or skin aging-related diseases, or as an active ingredient of a cosmetic composition for preventing skin damage caused by pollutants or for a skin anti-aging effect.
    Type: Grant
    Filed: April 23, 2019
    Date of Patent: September 6, 2022
    Assignee: CAREGEN CO., LTD.
    Inventors: Yong Ji Chung, Eun Mi Kim, Eung Ji Lee
  • Publication number: 20220265538
    Abstract: Provided are a peptide having an activity of promoting hair generation and use thereof. In particular, provided are a peptide consisting of an amino acid sequence of SEQ ID NO: 1, a composition including the peptide for improving hair loss or promoting hair generation, and a pharmaceutical composition including the peptide for preventing or treating hair loss.
    Type: Application
    Filed: October 10, 2019
    Publication date: August 25, 2022
    Inventors: Yongji CHUNG, Eun Mi KIM, Eung Ji LEE
  • Publication number: 20220259263
    Abstract: Provided are a peptide having an activity of promoting hair generation and use thereof. In particular, provided are a peptide consisting of an amino acid sequence of SEQ ID NO: 1, a composition including the peptide for improving hair loss or promoting hair generation, and a pharmaceutical composition including the peptide for preventing or treating hair loss.
    Type: Application
    Filed: October 10, 2019
    Publication date: August 18, 2022
    Inventors: Yongji CHUNG, Eun Mi KIM, Eung Ji LEE, Min Woong KIM
  • Publication number: 20220241174
    Abstract: Provided are a peptide having an activity of improving skin condition and use thereof. In particularly, provided are a peptide consisting of an amino acid sequence of SEQ ID NO: 1, a cosmetic composition including the peptide for improving skin condition, and a pharmaceutical composition including the peptide for preventing or treating an inflammatory skin disease.
    Type: Application
    Filed: October 10, 2019
    Publication date: August 4, 2022
    Inventors: Yongji CHUNG, Eun Mi KIM, Eung Ji LEE, Hana KANG
  • Publication number: 20220183949
    Abstract: Provided are a peptide having skin-whitening activity and use thereof, and a peptide consisting of an amino acid sequence of SEQ ID NO: 1, SEQ ID NO: 2, or SEQ ID NO: 3, a skin-whitening composition including the peptide, a cosmetic composition including the skin-whitening composition, and a pharmaceutical composition for preventing or treating a melanin hyperpigmentation disease, the pharmaceutical composition including the skin-whitening composition.
    Type: Application
    Filed: October 10, 2019
    Publication date: June 16, 2022
    Inventors: Yongji CHUNG, Eun Mi KIM, Eung Ji LEE, Jan Di KIM