Patents by Inventor Eunji CHA

Eunji CHA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof
    Patent number: 12590071
    Abstract: A compound represented by Formula 3 as described herein, or a pharmaceutically acceptable salt thereof, and a method of making a Formula 3 compound. In Formula 3: R1 is hydrogen; and Cy is unsubstituted benzothiazol-6-yl, benzothiazol-5-yl, quinolin-3-yl, indolyl, pyrrolopyridinyl, oxodihydrobenzothiazolyl, or oxodihydrobenzoxazolyl; or substituted benzothiazol-6-yl, benzothiazol-5-yl, indazolyl, quinolin-3-yl, indolyl, pyrrolopyridinyl, oxodihydrobenzothiazolyl, oxodihydrobenzoxazolyl, or oxodihydrobenzoimidazolyl, each of which is substituted with: (i) methyl, ethyl, propyl, butyl, isopropyl, isobutyl, methoxy, ethoxy, fluoro, chloro, bromo, trifluoroethyl, difluoromethyl, trifluoromethoxy, dimethylcarbamoyl, phenoxy, isopropoxy, methylamino or dimethylamino; or (ii) phenyl, pyridinyl, furanyl, or thiophenyl unsubstituted or substituted with at least one of methyl, fluoro, and dimethylamino. A compound of Formula 4 as described herein, or a pharmaceutically salt thereof.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: March 31, 2026
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Ae Nim Pae, Yun Kyung Kim, Sang Min Lim, Sungsu Lim, Jihye Seong, Jae Wook Lee, Ji Yeon Song, Seulgi Shin, Hyean Jeong Jeong, Woo Seung Son, Haeun Lee, Da Mi Lim, Seok Kyu Kim, Jee Yun Ahn, Chae Won Kim, Ashwini Machhindra Londhe, Lizaveta Gotina, Hyojin Kim, Hye Yeon Lee, Nam Gyung Kim, Eunji Cha, Kunhee Kim, Ji Woong Lim
  • Gingerol derivative having inhibitory activity against biofilm formation and pharmaceutical composition comprising same as effective ingredient for preventing or treating biofilm-caused infection symptom
    Patent number: 11964935
    Abstract: The present invention relates to a gingerol derivative having inhibitory activity against biofilm formation and a pharmaceutical composition for preventing or treating infections caused by biofilms including the gingerol derivative as an active ingredient. The gingerol derivative of the present invention exhibits significantly improved binding affinity for LasR and inhibitory activity against biofilm formation. Therefore, the gingerol derivative of the present invention can act on various membrane surfaces where biofilms tend to form and can effectively inhibit the formation of the corresponding biofilms. In addition, the use of the pharmaceutical composition according to the present invention can fundamentally prevent or treat a variety of infections caused by biofilms due to the presence of the gingerol derivative in the pharmaceutical composition.
    Type: Grant
    Filed: July 19, 2018
    Date of Patent: April 23, 2024
    Assignees: Korea University Research and Business Foundation, Sejong Campus, Korea University Research and Business Foundation
    Inventors: Youngjoo Byun, Hee-Deung Park, Sang-Hyun Son, Eunji Cha, So-Young Ham, Hyunsuk Choi
  • NOVEL HYDRAZONE DERIVATIVE IN WHICH TERMINAL AMINE GROUP IS SUBSTITUTED WITH ARYL GROUP OR HETEROARYL GROUP, AND USE THEREOF
    Publication number: 20220396553
    Abstract: The present invention relates to novel hydrazone derivatives in which a terminal amine group is substituted with an aryl group or a heteroaryl group, and uses thereof.
    Type: Application
    Filed: December 26, 2018
    Publication date: December 15, 2022
    Inventors: Ae Nim PAE, Yun Kyung KIM, Sang Min LIM, Sungsu LIM, Jihye SEONG, Jae Wook LEE, Ji Yeon SONG, Seulgi SHIN, Hyean Jeong JEONG, Woo Seung SON, Haeun LEE, Da Mi LIM, Seok Kyu KIM, Jee Yun AHN, Chae Won KIM, Ashwini Machhindra LONDHE, Lizaveta GOTINA, Hyojin KIM, Hye Yeon LEE, Nam Gyung KIM, Eunji CHA, Kunhee KIM, Ji Woong LIM
  • GINGEROL DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST BIOFILM FORMATION AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE INGREDIENT FOR PREVENTING OR TREATING BIOFILM-CAUSED INFECTION SYMPTOM
    Publication number: 20200283364
    Abstract: The present invention relates to a gingerol derivative having inhibitory activity against biofilm formation and a pharmaceutical composition for preventing or treating infections caused by biofilms including the gingerol derivative as an active ingredient. The gingerol derivative of the present invention exhibits significantly improved binding affinity for LasR and inhibitory activity against biofilm formation. Therefore, the gingerol derivative of the present invention can act on various membrane surfaces where biofilms tend to form and can effectively inhibit the formation of the corresponding biofilms. In addition, the use of the pharmaceutical composition according to the present invention can fundamentally prevent or treat a variety of infections caused by biofilms due to the presence of the gingerol derivative in the pharmaceutical composition.
    Type: Application
    Filed: July 19, 2018
    Publication date: September 10, 2020
    Applicants: Korea University Research and Business Foundation, Sejong Campus, Korea University Research and Business Foundation
    Inventors: Youngjoo BYUN, Hee-Deung PARK, Sang-Hyun SON, Eunji CHA, So-Young HAM, Hyunsuk CHOI