Abstract: The present invention relates to: a substituted thiazolidinedione derivative compound having a novel structure acting as a sterol regulatory element-binding protein-1 (SREBP1) inhibitor, a hydrate thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating cancer, comprising same as an active ingredient.

Abstract: The present invention relates to an ethylene/alpha-olefin copolymer having a high weight average molecular weight and narrow molecular weight distribution, and at the same time, a reduced characteristic relaxation time, thereby showing excellent physical properties, and a method for preparing the same. A resin composition having improved volume resistance and excellent light transmittance may be prepared by using such ethylene/alpha-olefin copolymer. Accordingly, the ethylene/alpha-olefin copolymer may be utilized in various uses in electrical and electronic industrial fields.

Abstract: Proposed is a blood-brain barrier penetrating drug delivery system in which sialyllactose, which can penetrate the blood-brain barrier, is linked to a drug. The drug delivery system can deliver low-molecular weight small molecule drugs and high-molecular weight antibodies to the brain, and thus can be applied to various types of brain disease therapeutic agents or diagnostic substances.

Abstract: A recycling method of a waste lithium ion secondary battery may include (a) charging a waste lithium ion secondary battery into a pyrolysis furnace, (b) increasing the internal temperature of the pyrolysis furnace to induce self-heating of the waste lithium ion secondary battery, (c) maintaining a self-heating reaction of the waste lithium ion secondary battery, (d) discharging a first powder formed after completing the self-heating reaction of the waste lithium ion secondary battery, and (e) injecting the first powder into water, dissolving a lithium component included in the first powder, and separating and recovering a lithium aqueous solution, a precipitate settled in the lithium aqueous solution, and a floating material on the surface of the lithium aqueous solution, separately.

Abstract: In a method for ameliorating or treating a respiratory disease, a composition including a Lysimachia mauritiana extract as effective component is administered to a subject in need thereof. Since the Lysimachia mauritiana extract is effective in reducing the production amount of the chemokine RANTES, an inflammatory mediator, from bronchial epithelial cells, which are respiratory cells, the composition can be advantageously used as a functional health food or medicine for respiratory diseases including asthma or chronic obstructive pulmonary disease (COPD).

Abstract: The present invention relates to a multi-stage decellularized mammal-derived tissue supplement, prepared by a method comprising: a preparation step for preparing tissue of a non-human mammal; a pretreatment step for pretreating the tissue; a first inactivation step for inactivating a virus included in the pretreated tissue using alcohol; a primary decellularization step for removing cells from the virus-inactivated tissue using an aqueous basic solution; a secondary decellularization step for removing cells by enzymatically treating the primary decellularized tissue; and a second inactivation step for inactivating a virus included in the decellularized tissue using an acid, and wherein the DNA content in the tissue subjected to the pretreatment step to the second inactivation step is 50 ng/mg or less, and the degradation time using 100 U/ml of collagenase is at least 90 hours; and a method for preparing the same.

Abstract: The present invention relates to a multi-stage decellularized mammal-derived tissue matrix, prepared by a method comprising: a preparation step for preparing tissue of a non-human mammal; a pretreatment step for pretreating the tissue; a first inactivation step for inactivating a virus included in the pretreated tissue using alcohol; a primary decellularization step for removing cells from the virus-inactivated tissue using an aqueous basic solution; a secondary decellularization step for removing cells by enzymatically treating the primary decellularized tissue; and a second inactivation step for inactivating a virus included in the decellularized tissue using an acid, and wherein the DNA content in the tissue subjected to the second inactivation step is 50 ng/mg or less, and the reduction rate (L) of the elastin content in the tissue subjected to the pretreatment step to the second inactivation step is 20% or less; and a method for preparing the same.

Abstract: The present disclosure relates to an isolated anti-FcRN antibody, which is an antibody binding to FcRN (stands for neonatal Fc receptor, also called FcRP, FcRB or Brambell receptor) that is a receptor with a high affinity for IgG or a fragment thereof, a method of preparing thereof, a composition for treating autoimmune disease, which comprises the antibody, and a method of treating and diagnosing autoimmunre diseases using the antibody. The FcRn-specific antibody according to the present disclosure binds to FcRn non-competitively with IgG to reduce serum pathogenic auto-antibody levels, and thus can be used for the treatment of autoimmune diseases.

Abstract: A method of fabricating a semiconductor device includes providing a substrate, forming a target film, a first mask film, a second mask film, and an upper mask pattern on the substrate, forming a first spacer pattern that includes a first line portion and a second line portion, and a folding portion that connects the first line portion and the second line portion, forming a slit mask pattern that partially covers the first spacer pattern, forming a first mask pattern by patterning the second mask film using the slit mask pattern and the first spacer pattern as an etching mask, forming a second spacer pattern, forming a second mask pattern by patterning the first mask film using the second spacer pattern as an etching mask, and forming a plurality of target patterns by patterning the target film using the second mask pattern as an etching mask.

Abstract: A multilayer ceramic electronic component includes a body including a dielectric layer and an internal electrode, and an external electrode disposed on the exterior of the body. The dielectric layer includes a plurality of dielectric grains and a grain boundary present between the dielectric grains. A molar ratio (Al/Ti) of Al and Ti included in the grain boundary satisfies 0.022 to 0.028.

Abstract: A reduced metal powder prepared by processing a waste lithium ion secondary battery to recover valuable metals from the waste lithium ion secondary battery in an economical and environmentally friendly manner is described. To achieve the goal described above, the reduced metal powder according to an embodiment is prepared by pyrolyzing a waste lithium ion secondary battery, and contains metals Ni and Co and has magnetism.

Abstract: There is provided a novel compound of Formula I and a use thereof for the prevention or treatment of a disease associated with SOS1. In one aspect of the present invention, the novel compound is useful for the prevention or treatment of a SOS1 mediated disease such as cancer and RASopathy by inhibiting the interaction between SOS1 and RAS family proteins or between SOS1 and RAC1.

Abstract: A polarizer includes a buffer member and linear metal patterns. The buffer member includes protrusions. Each protrusion has downwardly-increasing width. The buffer member is formed of polymer. The linear metal patterns, spaced apart from each other, are extended in a first direction. Each linear metal pattern covers a respective protrusion.

Abstract: The present disclosure relates to a sensing device and a method for processing sensing data.

Abstract: The present invention relates to a composition for treating neurodegenerative diseases comprising a beta blocker and a cholinesterase inhibitor and, more specifically, to a composition that relieves neuroinflammation, promotes nerve cell differentiation and shows antioxidant effects to exhibit synergistic effects on degenerative neurological diseases.

Abstract: Disclosed is a system operating method of identifying a type of user eating habits to recommend a food and provide a food report, the method including: receiving a request from a user to start chatting with a food recommendation chatbot operated by an account registered to a mobile messenger and providing food report content; presenting questions for identifying the type of user eating habits to the user, and analyzing the type of user eating habits based on responses entered by the user; providing a link to a result of the analyzed type of user eating habits to the user; receiving a request for a food recommendation from the user; providing a list of recommended foods reflecting the analyzed type of user eating habits to the user; providing nutritional information about a food, which is selected by the user from the list of recommended foods, to the user; and making a food report on the selected food and providing a link to the food report to the user, upon a response entered by the user to finally decide th

Abstract: Compositions and methods are described for alleviating, preventing, or treating adverse effects of cholinesterase inhibitors by administering an effective amount of an antioxidant to a subject in need thereof. Composition and methods are described for preventing or treating a brain disease by administering a cholinesterase inhibitor and an antioxidant to a subject in need thereof.

Abstract: A negative electrode for a rechargeable battery and a rechargeable battery including the same, the negative electrode includes a metal substrate including holes therein; a protective layer on the metal substrate, the protective layer including through holes therein overlying and in fluid communication with the holes in the metal substrate; and an electrolyte membrane including a liquid electrolyte layer and a solid electrolyte layer, the liquid electrolyte layer being in the holes and the solid electrolyte layer covering the protective layer and the through holes.

Abstract: Provided is a pharmaceutical composition for preventing or treating lupus-associated disease, including a GIP derivative, a pharmaceutically acceptable salt or solvate thereof, or a long-acting conjugate thereof.

Abstract: Disclosed is an organic light-emitting display device, which prevents lateral current leakage by providing a structure on a bank so as to cut off an organic material, which is formed in a subsequent process, around the structure.