Patents by Inventor EUNSIL CHO

EUNSIL CHO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11161888
    Abstract: The present invention relates to a method for regulating localization of CCNY protein to synapses, comprising palmitoylation of CCNY protein. Specifically, the present invention relates to a method for regulating targeting of CCNY protein to synapses by regulating addition of a palmitoyl group to cysteine at position 7 and/or 8 on the CCNY protein. Therefore, the palmitoylation of CCNY, a postsynaptic protein known to be implicated in synaptic plasticity and learning and memory, is a critical process for CCNY to be localized in postsynaptic spines, and thus it can be found that CCNY plays an important role in synaptic functions.
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: November 2, 2021
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Mikyoung Park, Yuri Choi, Jung-hwa Hong, Eunsil Cho
  • Patent number: 10724037
    Abstract: The present invention relates to a composition for improving memory including a Cyclin Y (CCNY) inhibitor as an active ingredient. More specifically, the present invention relates to a method for improving memory in a subject comprising administering the composition for improving memory to the subject. The present invention may reveal a CCNY-oriented molecular mechanism with respect to learning and memory, help understand causes of brain diseases associated with memory problems, and ultimately be applied in the treatment and diagnosis of brain memory disorders such as dementia.
    Type: Grant
    Filed: August 1, 2018
    Date of Patent: July 28, 2020
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Mikyoung Park, Eunsil Cho, Jung-Hwa Hong
  • Publication number: 20200140507
    Abstract: The present invention relates to a method for regulating localization of CCNY protein to synapses, comprising palmitoylation of CCNY protein. Specifically, the present invention relates to a method for regulating targeting of CCNY protein to synapses by regulating addition of a palmitoyl group to cysteine at position 7 and/or 8 on the CCNY protein. Therefore, the palmitoylation of CCNY, a postsynaptic protein known to be implicated in synaptic plasticity and learning and memory, is a critical process for CCNY to be localized in postsynaptic spines, and thus it can be found that CCNY plays an important role in synaptic functions.
    Type: Application
    Filed: October 29, 2019
    Publication date: May 7, 2020
    Inventors: Mikyoung PARK, Yuri CHOI, Jung-hwa HONG, Eunsil CHO
  • Publication number: 20180346911
    Abstract: The present invention relates to a composition for improving memory including a Cyclin Y (CCNY) inhibitor as an active ingredient. More specifically, the present invention relates to a method for improving memory in a subject comprising administering the composition for improving memory to the subject. The present invention may reveal a CCNY-oriented molecular mechanism with respect to learning and memory, help understand causes of brain diseases associated with memory problems, and ultimately be applied in the treatment and diagnosis of brain memory disorders such as dementia.
    Type: Application
    Filed: August 1, 2018
    Publication date: December 6, 2018
    Inventors: MIKYOUNG PARK, EUNSIL CHO, JUNG-HWA HONG
  • Patent number: 10131909
    Abstract: The present invention relates to a composition for improving memory including a Cyclin Y (CCNY) inhibitor as an active ingredient. More specifically, the present invention relates to a method for improving memory in a subject comprising administering the composition for improving memory to the subject. The present invention may reveal a CCNY-oriented molecular mechanism with respect to learning and memory, help understand causes of brain diseases associated with memory problems, and ultimately be applied in the treatment and diagnosis of brain memory disorders such as dementia.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: November 20, 2018
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Mikyoung Park, Eunsil Cho, Jung-Hwa Hong
  • Publication number: 20170226505
    Abstract: The present invention relates to a composition for improving memory including a Cyclin Y (CCNY) inhibitor as an active ingredient. More specifically, the present invention relates to a method for improving memory in a subject comprising administering the composition for improving memory to the subject. The present invention may reveal a CCNY-oriented molecular mechanism with respect to learning and memory, help understand causes of brain diseases associated with memory problems, and ultimately be applied in the treatment and diagnosis of brain memory disorders such as dementia.
    Type: Application
    Filed: July 19, 2016
    Publication date: August 10, 2017
    Inventors: MIKYOUNG PARK, EUNSIL CHO, JUNG-HWA HONG