Patents by Inventor Eusebio S. Pires

Eusebio S. Pires has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING CANCER
    Publication number: 20170298141
    Abstract: The present invention provides compositions for targeting SAS1B positive cancer cells using immunotoxin technology and discloses that kidney and pancreatic cancer cells are SAS1B positive, but not normal kidney and pancreatic cells. The invention discloses that despite being expressed only in growing oocytes in females among normal tissues SAS1B is expressed in cancers of both men and women.
    Type: Application
    Filed: April 28, 2017
    Publication date: October 19, 2017
    Applicant: University of Virginia Patent Foundation
    Inventors: John C. Herr, Eusebio S. Pires, Austin Herr
  • COMPOSITIONS AND METHODS FOR DETECTING, DIAGNOSING, AND TREATING CANCER
    Publication number: 20160195538
    Abstract: The present invention provides compositions and methods useful for diagnosing, treating, and preventing cancer, particularly ovarian cancer and uterine cancer, based on the discovery that the oocyte specific protein, SAS1R (Sperm Acrosomal SLLP1 Receptor), which is a sperm protein receptor, is also expressed in various cancers, including ovarian cancer and uterine cancer. Six SAS1R variants have been previously identified, and they are encompassed by the invention. The present invention further provides antibodies useful for targeting SAS1R expressing cells and for killing such cells.
    Type: Application
    Filed: December 28, 2015
    Publication date: July 7, 2016
    Inventors: John C. Herr, Eusebio S. Pires
  • COMPOSITIONS AND METHODS FOR TREATING CANCER
    Publication number: 20150125445
    Abstract: The present invention provides compositions for targeting SAS1B positive cancer cells using immunotoxin technology and discloses that kidney and pancreatic cancer cells are SAS1B positive, but not normal kidney and pancreatic cells. The invention discloses that despite being expressed only in growing oocytes in females among normal tissues SAS1B is expressed in cancers of both men and women.
    Type: Application
    Filed: June 13, 2013
    Publication date: May 7, 2015
    Inventors: John C. Herr, Eusebio S. Pires, Austin Herr
  • COMPOSITIONS AND METHODS FOR DETECTING, DIAGNOSING, AND TREATING CANCER
    Publication number: 20130164215
    Abstract: The present invention provides compositions and methods useful for diagnosing, treating, and preventing cancer, particularly ovarian cancer and uterine cancer, based on the discovery that the oocyte specific protein, SAS1R (Sperm Acrosomal SLL-P1 Receptor), which is a sperm protein receptor, is also expressed in various cancers, including ovarian cancer and uterine cancer. Six SAS1R variants have been previously identified, and they are encompassed by the invention. The present invention further provides antibodies useful for targeting SAS1R expressing cells and for killing such cells.
    Type: Application
    Filed: August 8, 2011
    Publication date: June 27, 2013
    Applicant: University of Virginia Patent Foundation,d/b/a University of Virginia Licensing & VenturesGroup
    Inventors: John C. Herr, Eusebio S. Pires