Patents by Inventor Eva Benedek

Eva Benedek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thiazoloisoquinolines with coronary and respiratory effects
    Patent number: 4163786
    Abstract: The invention relates to new thiazoloisoquinolines of the formula (I), or pharmaceutically acceptable salts thereof, ##STR1## wherein R.sup.1 is hydrogen, hydroxy, alkoxy or aralkoxy,R.sup.2 is hydrogen, hydroxy, alkoxy or aralkoxy,R.sup.3 is hydrogen, cyano, alkyl, aryl, nitro, carboxy, carboalkoxy or carboxamido, andY is oxygen, sulfur, or a group of the formula .dbd.N--R.sup.4, wherein R.sup.4 stands for hydrogen, alkyl, aryl, acyl, alkyl-sulfonyl or arysulfonyl.These new compounds can be used in practice as heart medicines or respiratory analeptics.
    Type: Grant
    Filed: January 16, 1978
    Date of Patent: August 7, 1979
    Assignee: Chinoin Pharmaceutical and Chemical Works Ltd.
    Inventors: Kalman Harsanyi, Kalman Takacs, Pal Kiss, Laszlo Szekeres, Gyula Papp, Eva Benedek
  • Thiazoloisoquinolines with coronary and respiratory effects
    Patent number: 4062850
    Abstract: 1-Cyano-2-imino-2H,4H-5,6-dihydro-8,9-dimethoxy-1,2-thiazolo(3,2a)isoquinol ine or 2-imino-2H,4H-5,6-dihydro-8,9-dimethoxy-1,2-thiazolo(3,2a)isoquinoline or a pharmaceutically acceptable salt thereof. These compounds are effective as heart medicines and respiratory analeptics.
    Type: Grant
    Filed: June 30, 1976
    Date of Patent: December 13, 1977
    Assignee: Chinoin Pharmaceutical and Chemical Works Ltd.
    Inventors: Kalman Harsanyi, Kalman Takacs, Pal Kiss, Laszlo Szekeres, Gyula Papp, Eva Benedek
  • Pharmaceutically effective novel 3,4-dihydro-1,2- and 1,3-thiozolo [4,3a] i s
    Patent number: 3979397
    Abstract: The invention relates to new thiazoloisoquinolines of the general formula (I), or salts thereof, ##SPC1##WhereinA stands for a group of the formula ##EQU1## R.sup.1 stands for hydrogen, hydroxy, alkoxy or aralkoxy, R.sup.2 stands for hydrogen, hydroxy, alkoxy or aralkoxy,R.sup.3 stands for hydrogen, alkyl, aryl, nitro, carboxy or a carboxy derivative, andY stands for oxygen, sulfur, or a group of the formula =N--R.sup.4, wherein R.sup.4 stands for hydrogen, alkyl, aryl, acyl, alkylsulfonyl or arylsulfonyl.These new compounds can be used in practice as heart medicines or respiratory analeptics.The new compounds according to the invention can be prepared as follows: an isoquinoline of the general formula (II) or a salt thereof ##SPC2##WhereinR.sup.5 stands for hydrogen, hydroxy, alkoxy or aralkoxy,R.sup.6 stands for hydrogen, hydroxy, alkoxy or aralkoxy,R.sup.
    Type: Grant
    Filed: May 28, 1974
    Date of Patent: September 7, 1976
    Assignee: Chinoin Pharmaceutical and Chemical Works Ltd.
    Inventors: Kalman Harsanyi, Kalman Takacs, Pal Kiss, Laszlo Szekeres, Gyula Papp, Eva Benedek