Patents by Inventor Eva Czirr

Eva Czirr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzodioxane Modulators of Leukotriene A4 Hydrolase (LTA4H) for Prevention and Treatment of Aging-Associated Diseases
    Publication number: 20240252478
    Abstract: This invention pertains to the prevention and treatment of aging-associated disease. The invention relates to the use of benzodioxane inhibitors of leukotriene production through modulation of leukotriene A4 hydrolase (“LTA4H”) to treat and/or prevent conditions associated with aging such as cognitive disorders, motor disorders, and neuroinflammation.
    Type: Application
    Filed: February 23, 2024
    Publication date: August 1, 2024
    Inventors: Meghan Kerrisk Campbell, Eva Czirr, Reema Harish
  • Benzodioxane modulators of leukotriene A4 hydrolase (LTA4H) for prevention and treatment of aging-associated diseases
    Patent number: 11957671
    Abstract: This invention pertains to the prevention and treatment of aging-associated disease. The invention relates to the use of benzodioxane inhibitors of leukotriene production through modulation of leukotriene A4 hydrolase (“LTA4H”) to treat and/or prevent conditions associated with aging such as cognitive disorders, motor disorders, and neuroinflammation.
    Type: Grant
    Filed: October 31, 2022
    Date of Patent: April 16, 2024
    Assignee: Alkahest, Inc.
    Inventors: Meghan Kerrisk Campbell, Eva Czirr, Reema Harish
  • Methods and Compositions for Treating Aging-Associated Impairments with Trefoil Factor Family Member 2 Modulators
    Publication number: 20240076369
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include agents modulating the biological concentrations of trefoil factor family member 2 (TFF2) with efficacy in treating and/or preventing aging-related conditions such as neurocognitive disorders.
    Type: Application
    Filed: May 5, 2022
    Publication date: March 7, 2024
    Inventors: Eva Czirr, Onkar S. Dhande, S. Sakura Minami, Balazs Szoke, Cindy Fu-Jeng Yang
  • Methods and Compositions for Treating Aging-Associated Impairments with TIMP-2 Recombinant Proteins
    Publication number: 20230399380
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include recombinant protein constructs employing human TIMP-2 protein for use in treating indications related to aging-related cognitive impairment.
    Type: Application
    Filed: May 9, 2023
    Publication date: December 14, 2023
    Inventors: Jody Berry, Elizabeth Booth, Rachel Britton, Meghan Kerrisk Campbell, Eva Czirr, Charles Holz, Tristan Wasley
  • Benzodioxane Modulators of Leukotriene A4 Hydrolase (LTA4H) for Prevention and Treatment of Aging-Associated Diseases
    Publication number: 20230146135
    Abstract: This invention pertains to the prevention and treatment of aging-associated disease. The invention relates to the use of benzodioxane inhibitors of leukotriene production through modulation of leukotriene A4 hydrolase (“LTA4H”) to treat and/or prevent conditions associated with aging such as cognitive disorders, motor disorders, and neuroinflammation.
    Type: Application
    Filed: October 31, 2022
    Publication date: May 11, 2023
    Inventors: Meghan Kerrisk Campbell, Eva Czirr, Reema Harish
  • Treatment of aging-associated disease with modulators of leukotriene A4 hydrolase
    Patent number: 11426399
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include inhibitors or antagonists of leukotriene A4 hydrolase (“LTA4H”) with efficacy in treating and/or preventing aging-related conditions such as neurocognitive disorders.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: August 30, 2022
    Assignee: Alkahest, Inc.
    Inventors: Meghan Kerrisk Campbell, Eva Czirr, Balazs Szoke
  • Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
    Patent number: 11413308
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include blood plasma and blood plasma fractions derived from blood plasma with efficacy in treating and/or preventing aging-related conditions such as cognitive disorders. The methods relate to a regimen of pulsed dosing of blood plasma or blood plasma fractions.
    Type: Grant
    Filed: November 13, 2020
    Date of Patent: August 16, 2022
    Assignee: Alkahest, Inc.
    Inventors: Steven P. Braithwaite, Eva Czirr, Ian Gallager, Nina Huber, S. Sakura Minami
  • Treatment of Aging-Associated Disease with Modulators of Leukotriene A4 Hydrolase
    Publication number: 20220226304
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include inhibitors or antagonists of leukotriene A4 hydrolase (“LTA4H”) with efficacy in treating and/or preventing aging-related conditions such as neurocognitive disorders.
    Type: Application
    Filed: March 22, 2022
    Publication date: July 21, 2022
    Inventors: Meghan Kerrisk Campbell, Eva Czirr, Balazs Szoke
  • Treatment of aging-associated disease with modulators of leukotriene Ahydrolase
    Patent number: 11344542
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include inhibitors or antagonists of leukotriene A4 hydrolase (“LTA4H”) with efficacy in treating and/or preventing aging-related conditions such as neurocognitive disorders.
    Type: Grant
    Filed: August 5, 2020
    Date of Patent: May 31, 2022
    Assignee: Alkahest, Inc.
    Inventors: Meghan Kerrisk Campbell, Eva Czirr, Balazs Szoke
  • Dosing Regimen for Treatment of Cognitive and Motor Impairments with Blood Plasma and Blood Plasma Products
    Publication number: 20210315932
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include blood plasma and blood plasma fractions derived from blood plasma with efficacy in treating and/or preventing aging-related conditions such as cognitive disorders. The methods relate to a regimen of pulsed dosing of blood plasma or blood plasma fractions.
    Type: Application
    Filed: May 18, 2021
    Publication date: October 14, 2021
    Inventors: Steven P. Braithwaite, Meghan Kerrisk Campbell, Eva Czirr, Ian Gallager, Nina Huber, Sam Jackson, S. Sakura Minami
  • Methods and Compositions for Treating Aging-Associated Impairments with Trefoil Factor Family Member 2 Modulators
    Publication number: 20210301013
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include agents modulating the biological concentrations of trefoil factor family member 2 (TFF2) with efficacy in treating and/or preventing aging-related conditions such as neurocognitive disorders.
    Type: Application
    Filed: May 12, 2021
    Publication date: September 30, 2021
    Inventors: Eva Czirr, Onkar S. Dhande, S. Sakura Minami, Balazs Szoke, Cindy Fu-Jeng Yang
  • Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
    Patent number: 11040068
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include blood plasma and blood plasma fractions derived from blood plasma with efficacy in treating and/or preventing aging-related conditions such as cognitive disorders. The methods relate to a regimen of pulsed dosing of blood plasma or blood plasma fractions.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: June 22, 2021
    Assignee: Alkahest, Inc.
    Inventors: Steven P. Braithwaite, Meghan Kerrisk Campbell, Eva Czirr, Ian Gallager, Nina Huber, Sam Jackson, S. Sakura Minami
  • Methods and Compositions for Treating Aging-Associated Impairments with Trefoil Factor Family Member 2 Modulators
    Publication number: 20210171626
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include agents modulating the biological concentrations of trefoil factor family member 2 (TFF2) with efficacy in treating and/or preventing aging-related conditions such as neurocognitive disorders.
    Type: Application
    Filed: November 25, 2020
    Publication date: June 10, 2021
    Inventors: Eva Czirr, Onkar S. Dhande, S. Sakura Minami, Balazs Szoke, Cindy Fu-Jeng Yang
  • Dosing Regimen for Treatment of Cognitive and Motor Impairments with Blood Plasma and Blood Plasma Products
    Publication number: 20210060063
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include blood plasma and blood plasma fractions derived from blood plasma with efficacy in treating and/or preventing aging-related conditions such as cognitive disorders. The methods relate to a regimen of pulsed dosing of blood plasma or blood plasma fractions.
    Type: Application
    Filed: November 13, 2020
    Publication date: March 4, 2021
    Inventors: Steven P. Braithwaite, Eva Czirr, Ian Gallager, Nina Huber, S. Sakura Minami
  • Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
    Patent number: 10874692
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include blood plasma and blood plasma fractions derived from blood plasma with efficacy in treating and/or preventing aging-related conditions such as cognitive disorders. The methods relate to a regimen of pulsed dosing of blood plasma or blood plasma fractions.
    Type: Grant
    Filed: June 5, 2019
    Date of Patent: December 29, 2020
    Assignee: Alkahest, Inc.
    Inventors: Steven P. Braithwaite, Eva Czirr, Ian Gallager, Nina Huber, S. Sakura Minami
  • Treatment of Aging-Associated Disease with Modulators of Leukotriene A4 Hydrolase
    Publication number: 20200368220
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include inhibitors or antagonists of leukotriene A4 hydrolase (“LTA4H”) with efficacy in treating and/or preventing aging-related conditions such as neurocognitive disorders.
    Type: Application
    Filed: August 5, 2020
    Publication date: November 26, 2020
    Inventors: Meghan Kerrisk Campbell, Eva Czirr, Balazs Szoke
  • Treatment of Aging-Associated Disease with Modulators of Leukotriene A4 Hydrolase
    Publication number: 20190350917
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include inhibitors or antagonists of leukotriene A4 hydrolase (“LTA4H”) with efficacy in treating and/or preventing aging-related conditions such as neurocognitive disorders.
    Type: Application
    Filed: May 14, 2019
    Publication date: November 21, 2019
    Inventors: Meghan Kerrisk Campbell, Eva Czirr, Balazs Szoke
  • Dosing Regimen for Treatment of Cognitive and Motor Impairments with Blood Plasma and Blood Plasma Products
    Publication number: 20190328782
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include blood plasma and blood plasma fractions derived from blood plasma with efficacy in treating and/or preventing aging-related conditions such as cognitive disorders. The methods relate to a regimen of pulsed dosing of blood plasma or blood plasma fractions.
    Type: Application
    Filed: July 11, 2019
    Publication date: October 31, 2019
    Inventors: Steven P. Braithwaite, Meghan Kerrisk Campbell, Eva Czirr, Ian Gallager, Nina Huber, Sam Jackson, S. Sakura Minami
  • Dosing Regimen for Treatment of Cognitive and Motor Impairments with Blood Plasma and Blood Plasma Products
    Publication number: 20190282617
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include blood plasma and blood plasma fractions derived from blood plasma with efficacy in treating and/or preventing aging-related conditions such as cognitive disorders. The methods relate to a regimen of pulsed dosing of blood plasma or blood plasma fractions.
    Type: Application
    Filed: June 5, 2019
    Publication date: September 19, 2019
    Inventors: Steven P. Braithwaite, Eva Czirr, Ian Gallager, Nina Huber, S. Sakura Minami
  • Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
    Patent number: 10357513
    Abstract: Methods and compositions for treating and/or preventing aging-related conditions are described. The compositions used in the methods include blood plasma and blood plasma fractions derived from blood plasma with efficacy in treating and/or preventing aging-related conditions such as cognitive disorders. The methods relate to a regimen of pulsed dosing of blood plasma or blood plasma fractions.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: July 23, 2019
    Assignee: Alkahest, Inc.
    Inventors: Steven P. Braithwaite, Eva Czirr, Ian Gallager, Nina Huber, S. Sakura Minami