Abstract: The invention provides for a novel cholesterol loaded insect cell membrane preparation having an increased cholesterol level as compared to physiological cholesterol levels of insect cell membranes or to control insect cell membrane preparations without cholesterol loading, wherein said cholesterol loaded membrane preparation comprises an ABC transporter protein having an increased substrate transport activity due to increased cholesterol level of the membrane. The invention also relates to reagent kits comprising the preparations of the invention. The invention also relates to methods for manufacturing said preparations and methods for measuring any type of activity of the ABC transporters present in the cholesterol loaded membranes as well as studying or testing compounds and interaction of compounds and ABC transporters, in this assay systems. The invention also provides for a test system useful for testing whether ABC transporter proteins can be activated by cholesterol in an insect cell membrane.

Abstract: The invention provides for a novel cholesterol loaded insect cell membrane preparation having an increased cholesterol level as compared to physiological cholesterol levels of insect cell membranes or to control insect cell membrane preparations without cholesterol loading, wherein said cholesterol loaded membrane preparation comprises an ABC transporter protein having an increased substrate transport activity due to increased cholesterol level of the membrane. The invention also relates to reagent kits comprising the preparations of the invention. The invention also relates to methods for manufacturing said preparations and methods for measuring any type of activity of the ABC transporters present in the cholesterol loaded membranes as well as studying or testing compounds and interaction of compounds and ABC transporters, in this assay systems. The invention also provides for a test system useful for testing whether ABC transporter proteins can be activated by cholesterol in an insect cell membrane.

Abstract: Multicomponent inclusion complexes characterized by the presence of an acidic drug, a base and a cyclodextrin are disclosed. Said complexes have a specific solubility in water.

Abstract: A method for the extraction of organic pollutants from contaminated soils without further contaminating the soil with organic solvents comprises the step of mixing aqueous solutions of cyclodextrins or their derivatives with the contaminated soil.

Abstract: The invention relates to cyclodextrin polymers swelling quickly and to a great extent in water and a process for the preparation thereof.The cyclodextrin polymers according to the invention contain as additive n-octanol having or glycol derivative or glycerol.The cyclodextrin polymers according to the invention are prepared by reacting cyclodextrin and epichlorohydrin in aqueous alkaline medium. In the reaction the cyclodextrin is reacted with 10 to 20 moles of an alkali hydroxide, 10 to 20 moles of epichlorohydrin and 2 to 8 moles of an alcohol additive, n-octanol, glycol derivative or glycerol calculated on 1 mole of cyclodextrin optionally in the presence of 10 to 15 moles of an organic solvent vaporizing at the reaction temperature or 8 to 12 moles of a high boiling organic solvent assuring heterogeneous phase.

Abstract: The invention relates to water soluble cyclodextrin polymers substituted by ionic groups, containing structural units of formula (I) ##STR1##

Abstract: The invention relates to new sorbents of cellulose basis capable of forming inclusion complexes, as well as to a process for the preparation thereof. The new sorbents according to the invention are cellulose derivatives containing structural units of the general formula (I), ##STR1## wherein Cell is a group derived by removing m hydroxy groups from the glucose unit of the cellulose chain,m is an integer of 1 to 3,CD is a group derived by removing one hydroxy group from the .alpha., .beta. or .gamma.-cyclodextrin molecule,n is an integer of 1 to 5, andp stands for 0 or 1, which may optionally vary even within a single chain.The cellulose derivatives according to the invention are substances of loose structure, with large specific surface area and good swelling properties, which can be applied for solving the most diverse adsorption tasks. Thus e.g.

Abstract: The present invention concerns new cyclodextrin-polyvinyl alcohol polymers capable of forming inclusion complexes. The preparation of said polymers by cross-linking a cyclodextrin, a mixture of cyclodextrins, or carbohydrate mixtures containing cyclodextrins in the presence of polyvinyl alcohol, polyvinyl acetate or a polyvinyl alcohol-polyvinyl acetate copolymer, with a polyfunctional coupling reactant capable of reacting with the cyclodextrins and with the polymers present is also within the scope of the invention.