Patents by Inventor Eva Hambruch

Eva Hambruch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LXR modulators with bicyclic core moiety
    Patent number: 11970484
    Abstract: The present invention relates to bicyclic compounds (e.g. indoles) containing a sulfonyl moiety, which bind to the liver X receptor (LXR? and/or LXK?) and act preferably as inverse agonists of LXR.
    Type: Grant
    Filed: February 9, 2023
    Date of Patent: April 30, 2024
    Assignee: OrsoBio, Inc.
    Inventors: Christian Gege, Olaf Kinzel, Eva Hambruch, Manfred Birkel, Claus Kremoser, Ulrich Deuschle
  • NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY
    Publication number: 20230357214
    Abstract: The present invention relates to bicyclic compounds (e.g. indoles) containing a sulfonyl moiety, which bind to the liver X receptor (LXR? and/or LXK?) and act preferably as inverse agonists of LXR.
    Type: Application
    Filed: February 9, 2023
    Publication date: November 9, 2023
    Inventors: Christian GEGE, Olaf KINZEL, Eva HAMBRUCH, Manfred BIRKEL, Claus KREMOSER, Ulrich DEUSCHLE
  • LXR modulators with bicyclic core moiety
    Patent number: 11618747
    Abstract: The present invention relates to bicyclic compounds (e.g. indoles) containing a sulfonyl moiety, which bind to the liver X receptor (LXR? and/or LXK?) and act preferably as inverse agonists of LXR.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: April 4, 2023
    Assignee: OrsoBio, Inc.
    Inventors: Christian Gege, Olaf Kinzel, Eva Hambruch, Manfred Birkel, Claus Kremoser, Ulrich Deuschle
  • NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY
    Publication number: 20210147398
    Abstract: The present invention relates to bicyclic compounds (e.g. indoles) containing a sulfonyl moiety, which bind to the liver X receptor (LXR? and/or LXK?) and act preferably as inverse agonists of LXR.
    Type: Application
    Filed: June 28, 2019
    Publication date: May 20, 2021
    Applicant: Phenex-FXR GmbH
    Inventors: Christian Gege, Olaf Kinzel, Eva Hambruch, Manfred Birkel, Claus Kremoser, Ulrich Deuschle
  • AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS
    Publication number: 20200131144
    Abstract: The present invention relates to derivatives of formula (I) which bind to the liver X receptor (LXR? and/or LXR?) and act preferably as inverse agonists of LXR.
    Type: Application
    Filed: July 18, 2018
    Publication date: April 30, 2020
    Applicant: Phenex-FXR GmbH
    Inventors: Christian Gege, Manfred Birkel, Eva Hambruch, Ulrich Deuschle, Claus Kremoser
  • LIVER X RECEPTORS (LXR) MODULATORS
    Publication number: 20200115357
    Abstract: The present invention relates to sulfonamide-, sulfinamide- or sulfonimidamide containing compounds which bind to the liver X receptor (LXRa and/or LXR?) and act preferably as inverse agonists of LXR.
    Type: Application
    Filed: April 10, 2018
    Publication date: April 16, 2020
    Applicant: Phenex-FXR GmbH
    Inventors: Christian Gege, Manfred Birkel, Eva Hambruch, Ulrich Deuschle, Claus Kremoser