Abstract: A tissue stimulating device that provides a biological stimulation of tissue has a release surface adapted for arrangement adjacent to a tissue to be stimulated. An agent reservoir of the device includes an ionic agent capable of causing a stimulation if present at sufficient high extracellular concentration close to the tissue. An agent releaser is provided in the device for releasing a selected amount of the ionic agent from the agent reservoir to an outside of the release surface at a stimulation occasion for stimulating the tissue. The ionic agent will cause a temporary change in ion permeability of the tissue cell membranes and a depolarization of the tissue cells.

Abstract: A medical implantable lead has a proximal end and a distal end, and a flexible flat elongate body. The elongate body includes a layer of strip conductors extending along the length of the flat elongate body, a top insulating layer, and a bottom insulating layer. The layer of strip conductors is sealingly enclosed between the top and bottom insulating layers, and at least a major portion of the flat elongate body is twisted into an elongate helical portion having a central cavity extending longitudinally of the helical portion.

Abstract: A tissue stimulating device that provides a biological stimulation of tissue has a release surface adapted for arrangement adjacent to a tissue to be stimulated. An agent reservoir of the device includes an ionic agent capable of causing a stimulation if present at sufficient high extracellular concentration close to the tissue. An agent releaser is provided in the device for releasing a selected amount of the ionic agent from the agent reservoir to an outside of the release surface at a stimulation occasion for stimulating the tissue. The ionic agent will cause a temporary change in ion permeability of the tissue cell membranes and a depolarization of the tissue cells.

Abstract: For treatment of cardiac tissue of a heart of a patient with therapeutic light using an implantable medical device connectable to at least one medical lead carrying electrodes and at least one fixation element that fixes the lead at a fixation area of the cardiac tissue, therapeutic light is emitted toward the at least one fixation area of cardiac tissue and/or toward a contact area between the at least one electrode and cardiac tissue using an intracorporeal light emitter.

Abstract: A medical implantable lead has a proximal end and a distal end, and a flexible flat elongate body. The elongate body includes a layer of strip conductors extending along the length of the flat elongate body, a top insulating layer, and a bottom insulating layer. The layer of strip conductors is sealingly enclosed between the top and bottom insulating layers, and at least a major portion of the flat elongate body is twisted into an elongate helical portion having a central cavity extending longitudinally of the helical portion.

Abstract: A implantable lead an elongate body including a flexible insulating tube, and a tubular conductor layer formed of multiple separate strip conductors, which are arranged at the outer surface of the insulating tube and extend along the length thereof.