Abstract: Pyrido[1,8]naphthyridinones of the general formula I ##STR1## in which R.sup.1 denotes hydrogen, a straight-chain or branched alkyl group having 1 to 6 carbon atoms, the phenyl group or a substituted phenyl group, a cycloalkyl group, a carboxyl group, an alkoxycarbonyl group, a carboxamide group or a cyano group,R.sup.2 denotes hydrogen or a straight-chain or branched alkyl group having 1 to 4 carbon atoms,R.sup.3 denotes hydrogen, a straight-chain or branched alkyl group having 1 to 4 carbon atoms, a carboxyl group, an alkoxycarbonyl group, a carboxamide group or a cyano group,R.sup.

Abstract: Substituted phenylpiperazinyl-propanols of the formula I ##STR1## in which R.sup.1 denotes hydrogen or an alkyl group with 1 to 4 carbon atoms and R.sup.2 and R.sup.3, which can be identical or different, each denote hydrogen, halogen, cyano, a trifluoromethyl group, a nitro group, a hydroxyl group, an alkoxy group or an alkyl group with in each case 1 to 4 carbon atoms, it being possible for the alkyl parts in each case to be straight-chain or branched, and their tautomeric forms and their salts as well as acid addition salts and N-oxides, have useful pharmacological properties, in particular a positively inotropic, vasodilating, broncholytic and platelet aggregation-inhibiting action and are therefore suitable for the treatment of cardiac insufficiency, hypertension, asthma and thrombosis.

Abstract: A compound of the formula ##STR1## wherein R.sup.1 is chlorine, bromine, or methoxy; and R.sup.2, R.sup.3, and R.sup.4 are individually hydrogen or methyl, at least one of R.sup.2, R.sup.3, and R.sup.4 being hydrogen; or R.sup.2 and R.sup.3 together are an ethylene group and R.sup.4 is hydrogen, or a pharmaceutically acceptable acid addition salt thereof. Such compounds are useful as anti-hypertensive agents. Methods of preparation and certain novel intermediates are also disclosed.