Patents by Inventor Eva Huala

Eva Huala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protease deficient bacterial hosts
    Patent number: 5143846
    Abstract: E. coli mutants which are capable of expressing cloned proteins in a highly stable manner are described.
    Type: Grant
    Filed: May 2, 1990
    Date of Patent: September 1, 1992
    Assignee: The General Hospital Corporation
    Inventors: Eva Huala, Frederick M. Ausubel
  • Oxygen regulatable gene expression
    Patent number: 4970147
    Abstract: The invention discloses that, in the presence of NifA and NtrA, the expression of a desired DNA molecule which has been operably linked to an ntrA-RNA polymerase and NifA dependent promoter can be regulated by regulating the oxygen level of the culture medium. The invention relates to vectors which may be used in accordance with this discovery, and to methods for using such vectors.
    Type: Grant
    Filed: March 17, 1988
    Date of Patent: November 13, 1990
    Assignee: The General Hospital Corporation
    Inventors: Eva Huala, Qing Gu, Lisa Albright, Frederick Ausubel