Patents by Inventor Eva Kabai
Eva Kabai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9790573Abstract: The present invention describes a method for purification of 225Ac from irradiated 226Ra-targets provided on a support comprising a leaching treatment of the 225Ra-targets for leaching essentially for the entirety of 223Ac and 226Ra with nitric or hydrochloric acid, followed by a first extraction chromatography for separating 225Ac from 226Ra and other Ra-isotops and a second extraction chromotography for separating 225Ac from 210Po and 210Pb. The finally purified 225Ac can be used to prepare compositions useful for pharmaceutical purposes.Type: GrantFiled: November 22, 2016Date of Patent: October 17, 2017Assignee: ACTINIUM PHARMACEUTICALS INC.Inventors: Josue Manuel Moreno Bermudez, Andreas Turler, Richard Henkelmann, Eva Kabai, Ernst Huenges
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Publication number: 20170137916Abstract: The present invention describes a method for purification of 225Ac from irradiated 226Ra-targets provided on a support comprising a leaching treatment of the 226Ra-targets for leaching essentially for the entirety of 223Ac and 226Ra with nitric or hydrochloric acid, followed by a first extraction chromatography for separating 225Ac from 226Ra and other Ra-isotops and a second extraction chromotography for separating 223Ac from 210Po and 210Pb. The finally purified 225Ac can be used to prepare compositions useful for pharmaceutical purposes.Type: ApplicationFiled: November 22, 2016Publication date: May 18, 2017Inventors: Josue Manuel MORENO BERMUDEZ, Andreas TURLER, Richard HENKELMANN, Eva KABAI, Ernst HUENGES
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Publication number: 20170009320Abstract: The present invention describes a method for purification of 225Ac from irradiated 226Ra-targets provided on a support, comprising a leaching treatment of the 226Ra-targets for leaching essentially the entirety of 225Ac and 226Ra with nitric or hydrochloric acid, followed by a first extraction chromatography separating 25Ac from 226Ra and other Ra-isotopes and a second extraction chromatography for separating 225Ac from 210Po and 210Pb. The finally purified 225Ac can be used to prepare compositions useful for pharmaceutical purposes.Type: ApplicationFiled: March 31, 2014Publication date: January 12, 2017Applicant: ACTINIUM PHARMACEUTICALS INC.Inventors: Josue Manuel MORENO BERMUDEZ, Andreas TURLER, Richard HENKELMANN, Eva KABAI, Ernst HUENGES
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Patent number: 9534277Abstract: The present invention describes a method for purification of 225Ac from irradiated 226Ra-targets provided on a support, comprising a leaching treatment of the 226Ra-targets for leaching essentially the entirety of 225Ac and 226Ra with nitric or hydrochloric acid, followed by a first extraction chromatography for separating 225Ac from 226Ra and other Ra-isotops and a second extraction chromatography for separating 225Ac from 210Po and 210Pb. The finally purified 225Ac can be used to prepare compositions useful for pharmaceutical purposes.Type: GrantFiled: March 31, 2014Date of Patent: January 3, 2017Assignee: ACTINIUM PHARMACEUTICALS, INC.Inventors: Josue Manuel Moreno Bermudez, Andreas Turler, Richard Henkelmann, Eva Kabai, Ernst Huenges
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Patent number: 8715598Abstract: The invention is directed to a method for the purification of Radium, in particular 226Ra, for target preparation for an essentially pure 225Ac production from available radioactive sources, using an extraction chromatography in order to separate chemically similar elements such as Ba, Sr, and Pb from the desired Ra; wherein said extraction chromatography has an extractant system on the basis of a crown ether. The invention is related to a method for recycling of 226Ra, for target preparation for 225Ac production from radium sources irradiated with accelerated protons (p,2n), after separation of the produced 225Ac. In this method a combination of the above extraction chromatography and a cation exchange chromatography is used. The obtained 226Ra is essentially free of the following chemical contaminants consisting of Ag, Al, As, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, Ga, K, Li, Mg, Mn, Na, Ni, Pb, Sr, V, Zn, and Ba.Type: GrantFiled: April 6, 2012Date of Patent: May 6, 2014Assignee: Actinium Pharmaceuticals Inc.Inventors: Eva Kabai, Josue M. Moreno Bermudez, Richard Henkelmann, Andreas Türler
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Publication number: 20130266475Abstract: The present invention describes a method for purification of 225Ac from irradiated 226Ra-targets provided on support, comprising a leaching treatment of the 226Ra-targets for leaching essentially the entirety of 225Ac and 226Ra with nitric or hydrochloric acid, followed by a first extraction chromatography for separating 225Ac from 226Ra and other Ra-isotopes and a second extraction chromatography for separating 225Ac from 210Po and 210Pb. The finally purified 225Ac can be used to prepare compositions useful for pharmaceutical purposes.Type: ApplicationFiled: May 13, 2013Publication date: October 10, 2013Inventors: Josue Manuel MORENO BERMUDEZ, Andreas TURLER, Richard HENKELMANN, Eva KABAI, Ernst HUENGES
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Publication number: 20120251415Abstract: The invention is directed to a method for the purification of Radium, in particular 226Ra, for target preparation for an essentially pure 225Ac production from available radioactive sources, using an extraction chromatography in order to separate chemically similar elements such as Ba, Sr, and Pb from the desired Ra; wherein said extraction chromatography has an extractant system on the basis of a crown ether. The invention is related to a method for recycling of 226Ra, for target preparation for 225Ac production from radium sources irradiated with accelerated protons (p,2n), after separation of the produced 225Ac. In this method a combination of the above extraction chromatography and a cation exchange chromatography is used. The obtained 226Ra is essentially free of the following chemical contaminants consisting of Ag, Al, As, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, Ga, K, Li, Mg, Mn, Na, Ni, Pb, Sr, V, Zn, and Ba.Type: ApplicationFiled: April 6, 2012Publication date: October 4, 2012Applicant: Actinium Pharmaceuticals Inc.Inventors: Eva KABAI, Josue M. MORENO BERMUDEZ, Richard HENKELMANN, Andreas Türler
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Patent number: 8153087Abstract: The present application is directed to a method for the purification of Radium, in particular 226Ra, for target preparation for an essentially pure 225Ac production from available radioactive sources, using an extraction chromatography in order to separate chemically similar elements such as Ba, Sr, and Pb from the desired Ra; wherein said extraction chromatography has an extractant system on the basis of a crown ether. The invention is further related to a method for recycling of 226Ra, for target preparation for 225Ac production from radium sources irradiated with accelerated protons (p,2n), after separation of the produced 225AC. In this method a combination of the above extraction chromatography and a cation exchange chromatography is used. The obtained 226Ra is essentially free of the following chemical contaminants consisting of Ag, Al, As, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, Ga, K, Li, Mg, Mn, Na, Ni, Pb, Sr, V, Zn, and Ba.Type: GrantFiled: March 5, 2009Date of Patent: April 10, 2012Assignee: Actinium Pharmaceuticals Inc.Inventors: Eva Kabai, Josue Manuel Moreno Bermudez, Richard Henkelmann, Andreas Turler
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Publication number: 20100104489Abstract: The present application is directed to a method for the purification of Radium, in particular 226Ra, for target preparation for an essentially pure 225Ac production from available radioactive sources, using an extraction chromatography in order to separate chemically similar elements such as Ba, Sr, and Pb from the desired Ra; wherein said extraction chromatography has an extractant system on the basis of a crown ether. The invention is further related to a method for recycling of 226Ra, for target preparation for 225Ac production from radium sources irradiated with accelerated protons (p,2n), after separation of the produced 225AC. In this method a combination of the above extraction chromatography and a cation exchange chromatography is used. The obtained 226Ra is essentially free of the following chemical contaminants consisting of Ag, Al, As, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, Ga, K, Li, Mg, Mn, Na, Ni, Pb, Sr, V, Zn, and Ba.Type: ApplicationFiled: March 5, 2009Publication date: April 29, 2010Applicant: Actinium Pharmaceuticals Inc.Inventors: Eva Kabai, Josue M. Moreno Bermudez, Richard Henklemann, Andreas Turler
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Publication number: 20090191122Abstract: The present invention describes a method for purification of 225Ac from irradiated 226Ra-targets provided on a support, comprising a leaching treatment of the 226Ra-targets for leaching essentially the entirety of 225Ac and 226Ra with nitric or hydrochloric acid, followed by a first extraction chromatography for separating 225Ac from 226Ra and other Ra-isotopes and a second extraction chromatography for separating 225Ac from 210Po and 210Pb. The finally purified 225Ac can be used to prepare compositions useful for pharmaceutical purposes.Type: ApplicationFiled: February 19, 2007Publication date: July 30, 2009Applicant: ACTINIUM PHARMACEUTICALS INC.Inventors: Josue Manuel Moreno Bermudez, Andreas Turler, Richard Henklemann, Eva Kabai, Ernst Huenges