Patents by Inventor Eva Kabai

Eva Kabai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9790573
    Abstract: The present invention describes a method for purification of 225Ac from irradiated 226Ra-targets provided on a support comprising a leaching treatment of the 225Ra-targets for leaching essentially for the entirety of 223Ac and 226Ra with nitric or hydrochloric acid, followed by a first extraction chromatography for separating 225Ac from 226Ra and other Ra-isotops and a second extraction chromotography for separating 225Ac from 210Po and 210Pb. The finally purified 225Ac can be used to prepare compositions useful for pharmaceutical purposes.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: October 17, 2017
    Assignee: ACTINIUM PHARMACEUTICALS INC.
    Inventors: Josue Manuel Moreno Bermudez, Andreas Turler, Richard Henkelmann, Eva Kabai, Ernst Huenges
  • Publication number: 20170137916
    Abstract: The present invention describes a method for purification of 225Ac from irradiated 226Ra-targets provided on a support comprising a leaching treatment of the 226Ra-targets for leaching essentially for the entirety of 223Ac and 226Ra with nitric or hydrochloric acid, followed by a first extraction chromatography for separating 225Ac from 226Ra and other Ra-isotops and a second extraction chromotography for separating 223Ac from 210Po and 210Pb. The finally purified 225Ac can be used to prepare compositions useful for pharmaceutical purposes.
    Type: Application
    Filed: November 22, 2016
    Publication date: May 18, 2017
    Inventors: Josue Manuel MORENO BERMUDEZ, Andreas TURLER, Richard HENKELMANN, Eva KABAI, Ernst HUENGES
  • Publication number: 20170009320
    Abstract: The present invention describes a method for purification of 225Ac from irradiated 226Ra-targets provided on a support, comprising a leaching treatment of the 226Ra-targets for leaching essentially the entirety of 225Ac and 226Ra with nitric or hydrochloric acid, followed by a first extraction chromatography separating 25Ac from 226Ra and other Ra-isotopes and a second extraction chromatography for separating 225Ac from 210Po and 210Pb. The finally purified 225Ac can be used to prepare compositions useful for pharmaceutical purposes.
    Type: Application
    Filed: March 31, 2014
    Publication date: January 12, 2017
    Applicant: ACTINIUM PHARMACEUTICALS INC.
    Inventors: Josue Manuel MORENO BERMUDEZ, Andreas TURLER, Richard HENKELMANN, Eva KABAI, Ernst HUENGES
  • Patent number: 9534277
    Abstract: The present invention describes a method for purification of 225Ac from irradiated 226Ra-targets provided on a support, comprising a leaching treatment of the 226Ra-targets for leaching essentially the entirety of 225Ac and 226Ra with nitric or hydrochloric acid, followed by a first extraction chromatography for separating 225Ac from 226Ra and other Ra-isotops and a second extraction chromatography for separating 225Ac from 210Po and 210Pb. The finally purified 225Ac can be used to prepare compositions useful for pharmaceutical purposes.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: January 3, 2017
    Assignee: ACTINIUM PHARMACEUTICALS, INC.
    Inventors: Josue Manuel Moreno Bermudez, Andreas Turler, Richard Henkelmann, Eva Kabai, Ernst Huenges
  • Patent number: 8715598
    Abstract: The invention is directed to a method for the purification of Radium, in particular 226Ra, for target preparation for an essentially pure 225Ac production from available radioactive sources, using an extraction chromatography in order to separate chemically similar elements such as Ba, Sr, and Pb from the desired Ra; wherein said extraction chromatography has an extractant system on the basis of a crown ether. The invention is related to a method for recycling of 226Ra, for target preparation for 225Ac production from radium sources irradiated with accelerated protons (p,2n), after separation of the produced 225Ac. In this method a combination of the above extraction chromatography and a cation exchange chromatography is used. The obtained 226Ra is essentially free of the following chemical contaminants consisting of Ag, Al, As, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, Ga, K, Li, Mg, Mn, Na, Ni, Pb, Sr, V, Zn, and Ba.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: May 6, 2014
    Assignee: Actinium Pharmaceuticals Inc.
    Inventors: Eva Kabai, Josue M. Moreno Bermudez, Richard Henkelmann, Andreas Türler
  • Publication number: 20130266475
    Abstract: The present invention describes a method for purification of 225Ac from irradiated 226Ra-targets provided on support, comprising a leaching treatment of the 226Ra-targets for leaching essentially the entirety of 225Ac and 226Ra with nitric or hydrochloric acid, followed by a first extraction chromatography for separating 225Ac from 226Ra and other Ra-isotopes and a second extraction chromatography for separating 225Ac from 210Po and 210Pb. The finally purified 225Ac can be used to prepare compositions useful for pharmaceutical purposes.
    Type: Application
    Filed: May 13, 2013
    Publication date: October 10, 2013
    Inventors: Josue Manuel MORENO BERMUDEZ, Andreas TURLER, Richard HENKELMANN, Eva KABAI, Ernst HUENGES
  • Publication number: 20120251415
    Abstract: The invention is directed to a method for the purification of Radium, in particular 226Ra, for target preparation for an essentially pure 225Ac production from available radioactive sources, using an extraction chromatography in order to separate chemically similar elements such as Ba, Sr, and Pb from the desired Ra; wherein said extraction chromatography has an extractant system on the basis of a crown ether. The invention is related to a method for recycling of 226Ra, for target preparation for 225Ac production from radium sources irradiated with accelerated protons (p,2n), after separation of the produced 225Ac. In this method a combination of the above extraction chromatography and a cation exchange chromatography is used. The obtained 226Ra is essentially free of the following chemical contaminants consisting of Ag, Al, As, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, Ga, K, Li, Mg, Mn, Na, Ni, Pb, Sr, V, Zn, and Ba.
    Type: Application
    Filed: April 6, 2012
    Publication date: October 4, 2012
    Applicant: Actinium Pharmaceuticals Inc.
    Inventors: Eva KABAI, Josue M. MORENO BERMUDEZ, Richard HENKELMANN, Andreas Türler
  • Patent number: 8153087
    Abstract: The present application is directed to a method for the purification of Radium, in particular 226Ra, for target preparation for an essentially pure 225Ac production from available radioactive sources, using an extraction chromatography in order to separate chemically similar elements such as Ba, Sr, and Pb from the desired Ra; wherein said extraction chromatography has an extractant system on the basis of a crown ether. The invention is further related to a method for recycling of 226Ra, for target preparation for 225Ac production from radium sources irradiated with accelerated protons (p,2n), after separation of the produced 225AC. In this method a combination of the above extraction chromatography and a cation exchange chromatography is used. The obtained 226Ra is essentially free of the following chemical contaminants consisting of Ag, Al, As, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, Ga, K, Li, Mg, Mn, Na, Ni, Pb, Sr, V, Zn, and Ba.
    Type: Grant
    Filed: March 5, 2009
    Date of Patent: April 10, 2012
    Assignee: Actinium Pharmaceuticals Inc.
    Inventors: Eva Kabai, Josue Manuel Moreno Bermudez, Richard Henkelmann, Andreas Turler
  • Publication number: 20100104489
    Abstract: The present application is directed to a method for the purification of Radium, in particular 226Ra, for target preparation for an essentially pure 225Ac production from available radioactive sources, using an extraction chromatography in order to separate chemically similar elements such as Ba, Sr, and Pb from the desired Ra; wherein said extraction chromatography has an extractant system on the basis of a crown ether. The invention is further related to a method for recycling of 226Ra, for target preparation for 225Ac production from radium sources irradiated with accelerated protons (p,2n), after separation of the produced 225AC. In this method a combination of the above extraction chromatography and a cation exchange chromatography is used. The obtained 226Ra is essentially free of the following chemical contaminants consisting of Ag, Al, As, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, Ga, K, Li, Mg, Mn, Na, Ni, Pb, Sr, V, Zn, and Ba.
    Type: Application
    Filed: March 5, 2009
    Publication date: April 29, 2010
    Applicant: Actinium Pharmaceuticals Inc.
    Inventors: Eva Kabai, Josue M. Moreno Bermudez, Richard Henklemann, Andreas Turler
  • Publication number: 20090191122
    Abstract: The present invention describes a method for purification of 225Ac from irradiated 226Ra-targets provided on a support, comprising a leaching treatment of the 226Ra-targets for leaching essentially the entirety of 225Ac and 226Ra with nitric or hydrochloric acid, followed by a first extraction chromatography for separating 225Ac from 226Ra and other Ra-isotopes and a second extraction chromatography for separating 225Ac from 210Po and 210Pb. The finally purified 225Ac can be used to prepare compositions useful for pharmaceutical purposes.
    Type: Application
    Filed: February 19, 2007
    Publication date: July 30, 2009
    Applicant: ACTINIUM PHARMACEUTICALS INC.
    Inventors: Josue Manuel Moreno Bermudez, Andreas Turler, Richard Henklemann, Eva Kabai, Ernst Huenges