Patents by Inventor Eva L. K. Enmark

Eva L. K. Enmark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Orphan receptor
    Patent number: 7132261
    Abstract: This invention relates to a novel estrogen receptor-related nuclear receptor, hereinafter termed “ER?” having the amino acid sequence of FIG. 1, 13A or 14A or substantially the same amino acid sequence as the amino acid sequence shown in FIG. 1, 13A or 13B or an amino acid sequence functionally similar to that sequence. The invention also relates to DNA sequences encoding the receptor. The receptor may be useful in isolating molecules for the treatment of disorders such as prostate cancer, benign prostatic hyperplasia, osteoporosis or cardiovascular disorders and in the testing of substances for estrogenic and other hormonal effects.
    Type: Grant
    Filed: October 23, 2002
    Date of Patent: November 7, 2006
    Assignee: Karo Bio AB
    Inventors: Georg Kuiper, Eva L. K. Enmark, Jan-Ake Gustafsson
  • Method of conferring 9-CIS retionic acid reponsiveness
    Patent number: 6617120
    Abstract: This invention provides an isolated receptor having the amino acid sequence of FIG. 1 (SEQ ID NO:2) or substantially the same amino acid sequence as the amino acid sequence shown in FIG. 1 (SEQ ID NO:2) or an amino acid sequence functionally similar to that sequence, and DNA sequences encoding such a receptor.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: September 9, 2003
    Assignee: Karo Bio AB
    Inventors: Eva L. K. Enmark, Jan-Ake Gustafsson
  • Orphan receptor
    Publication number: 20030113803
    Abstract: This invention relates to a novel estrogen receptor-related nuclear receptor, hereinafter termed “ER&bgr;” having the amino acid sequence of FIGS. 1, 13A or 14A or substantially the same amino acid sequence as the amino acid sequence shown in FIGS. 1, 13A or 13B or an amino acid sequence functionally similar to that sequence. The invention also relates to DNA sequences encoding the receptor. The receptor may be useful in isolating molecules for the treatment of disorders such as prostate cancer, benign prostatic hyperplasia, osteoporosis or cardiovascular disorders and in the testing of substances for estrogenic and other hormonal effects.
    Type: Application
    Filed: October 23, 2002
    Publication date: June 19, 2003
    Inventors: Georg Kuiper, Eva L. K. Enmark, Jan-Ake Gustafsson
  • Nuclear retinoic acid co-receptor
    Patent number: 6525188
    Abstract: This invention provides an isolated receptor having the amino acid sequence of FIG. 1 (SEQ ID NO:2) or substantially the same amino acid sequence as the amino acid sequence shown in FIG. 1 (SEQ ID NO:2) or an amino acid sequence functionally similar to that sequence, and DNA sequences encoding such a receptor.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: February 25, 2003
    Assignee: Karo Bio Ab
    Inventors: Eva L. K. Enmark, Jan-Ake Gustafsson
  • Orphan receptor
    Publication number: 20020128461
    Abstract: This invention provides an isolated receptor having the amino acid sequence of FIG. 1 (SEQ ID NO:2) or substantially the same amino acid sequence as the amino acid sequence shown in FIG. 1 (SEQ ID NO:2) or an amino acid sequence functionally similar to that sequence, and DNA sequences encoding such a receptor.
    Type: Application
    Filed: July 19, 2001
    Publication date: September 12, 2002
    Inventors: Eva L.K. Enmark, Jan-Ake Gustafsson
  • Orphan receptor
    Publication number: 20020115847
    Abstract: This invention provides an isolated receptor having the amino acid sequence of FIG. 1 (SEQ ID NO:2) or substantially the same amino acid sequence as the amino acid sequence shown in FIG. 1 (SEQ ID NO:2) or an amino acid sequence functionally similar to that sequence, and DNA sequences encoding such a receptor.
    Type: Application
    Filed: July 19, 2001
    Publication date: August 22, 2002
    Inventors: Eva L.K. Enmark, Jan-Ake Gustafsson
  • Orphan receptor
    Publication number: 20020052489
    Abstract: This invention provides an isolated receptor having the amino acid sequence of FIG. 1 (SEQ ID NO:2) or substantially the same amino acid sequence as the amino acid sequence shown in FIG. 1 (SEQ ID NO:2) or an amino acid sequence functionally similar to that sequence, and DNA sequences encoding such a receptor.
    Type: Application
    Filed: July 19, 2001
    Publication date: May 2, 2002
    Inventors: Eva L.K. Enmark, Jan-Ake Gustafsson
  • Or-1, an orphan receptor belonging to the nuclear receptor family
    Patent number: 6277976
    Abstract: This invention provides an isolated receptor having the amino acid sequence of FIG. 1 (SEQ ID NO:2) or substantially the same amino acid sequence as the amino acid sequence shown in FIG. 1 (SEQ ID NO:2) or an amino acid sequence functionally similar to that sequence, and DNA sequences encoding such a receptor.
    Type: Grant
    Filed: June 24, 1997
    Date of Patent: August 21, 2001
    Assignee: Karo Bio AB
    Inventors: Eva L. K. Enmark, Jan-Ake Gustafsson
  • Orphan receptor
    Patent number: 5958710
    Abstract: This invention relates to a novel estrogen receptor-related nuclear receptor, hereinafter termed "ER.beta." having the amino acid sequence of FIGS. 1, 13A or 14A or substantially the same ambino acid sequence as the amino acid sequence shown in FIGS. 1, 13A or 13B or an amino acid sequence functionally similar to that sequence. The invention also relates to DNA sequences encoding the receptor. The receptor may be useful in isolating molecules for the treatment of disorders such as prostate cancer, benign prostatic hyperplasia, osteoporosis or cardiovascular disorders and in the testing of substances for estrogenic and other hormonal effects.
    Type: Grant
    Filed: May 8, 1997
    Date of Patent: September 28, 1999
    Assignee: Karo Bio AB
    Inventors: Georg Kuiper, Eva L. K. Enmark, Jan-Ake Gustafsson