Abstract: A gel for dental caries prevention is disclosed, comprising a gelling agent, a humectant, a surface active material, a flavoring material, 1.7-11% by weight of an anti-caries agent which is a mixture of sodium monofluorophosphate with a substance obtained from treating the bone tissue with a diluted mineral acid to completely remove the mineral components and water-soluble proteins contained in bone tissue, isolation of the thus obtained solution, diluting it with water and stabilizing additives of citric acid or salts thereof, with subsequent neutralization of the solution and drying, and including the following parts and proportions by weight %:______________________________________ calcium 2-6 sodium 19-23 potassium 0.04-0.18 anion of mineral acid 6-10.6 anion of orthophosphoric 1.5-5.0 acid water-soluble proteins 1.0-5.0 magnesium 0.05-0.2 complex of microelements 0.01-0.02 including fluorine, manganese, tin, zinc, iron complex citrate compounds the rest.