Abstract: A major challenge in vaccinology is to prospectively determine vaccine efficacy. Disclosed herein are methods and compositions for identifying early expression “signatures” that predicted immune responses in humans vaccinated with a vaccine.

Abstract: Disclosed are methods of controlling cell cycle progression by introducing into a cell to be controlled a composition selected from the group consisting of p56RB protein, a fragment of the p56RB protein, and the gene encoding p56RB protein to alter the cell cycle progression while maintaining the viability of the cell. The p56RB protein has been found to have the unexpected and surprising characteristic of being soluble in low concentrations of glycerol, thereby enhancing its value in pharmaceutical applications and the gene encoding p56RB when delivered to the hyperproliferating cell inhibits cellular proliferation.

Abstract: In a manufacturing process management system 10, each of input terminals 401 to 40n located respectively in multiple manufacturing processes of a process flow with regard to a preset product reads a barcode 164 attached to a target 160 and inputs a start of processing with regard to the product. The manufacturing process management system 10 maps the product to a processing status and stores the mapping into a database 130. In response to input of an acquisition request of the processing status with regard to the product from a client PC 50, the manufacturing process management system 10 reads the processing status according to the acquisition request from the database 130, creates a response message, and outputs the created response message to the client PC 50. This manufacturing process management system enables a current location of the preset product to be readily managed in the process flow of the multiple manufacturing processes.

Abstract: In a manufacturing process management system 10, each of input terminals 401 to 40n located respectively in multiple manufacturing processes of a process flow with regard to a preset product reads a barcode 164 attached to a target 160 and inputs a start of processing with regard to the product. The manufacturing process management system 10 maps the product to a processing status and stores the mapping into a database 130. In response to input of an acquisition request of the processing status with regard to the product from a client PC 50, the manufacturing process management system 10 reads the processing status according to the acquisition request from the database 130, creates a response message, and outputs the created response message to the client PC 50. This manufacturing process management system enables a current location of the preset product to be readily managed in the process flow of the multiple manufacturing processes.