Patents by Inventor Eva M. Munoz

Eva M. Munoz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENZYMATIC SYNTHESIS OF SULFATED POLYSACCHARIDES
    Publication number: 20120322114
    Abstract: Heparosan is sulfated at the iduronic acid residue by providing a reaction mixture comprising C5 epimerase to convert glucuronic acid to iduronic acid, and at least one O-sulfotransferase (OST) enzyme and 3?-phosphoadenosine 5?-phosphosulfate (PAPS).
    Type: Application
    Filed: March 12, 2012
    Publication date: December 20, 2012
    Inventors: Jian Liu, Robert J. Linhardt, Fikri Y. Avci, Eva M. Munoz, Jinghua Chen
  • Enzymatic synthesis of sulfated polysaccharides
    Publication number: 20090197308
    Abstract: A method of sulfating a polysaccharide is provided. The method can include providing a reaction mixture comprising at least one O-sulfotransferase (OST) enzyme and 3?-phosphoadenosine 5?-phosphosulfate (PAPS); incubating a polysaccharide substrate with the reaction mixture, wherein production of the sulfated polysaccharide from the polysaccharide substrate is catalyzed by the OST enzyme with a conversion of the PAPS to adenosine 3?,5?-diphosphate (PAP); and providing a reaction condition which modifies PAP to reduce an inhibitory effect of PAP on the polysaccharide sulfation.
    Type: Application
    Filed: May 12, 2006
    Publication date: August 6, 2009
    Inventors: Jian Liu, Robert J. Linhardt, Fikri Y. Avci, Eva M. Munoz, Jinghua Chen