Patents by Inventor Eva Maturova

Eva Maturova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5177204
    Abstract: This relates to substances represented by formula (I), wherein X stands for represented by either OR in which R is an alkyl of 1 to 4 carbon atoms, or NHR in which is an alkyl of 1 to 4 carbon atoms, or a (CH.sub.2).sub.n NR.sub.2 group wherein n is 2 or 3 while R.sup. is an methyl or an ethyl group; eventually X may represent morpholinyl. Also considered are salts of 4-(2,4-difluorbiphenylyl)-2-methyl-4-oxobutanoic acid with appropriate inorganic or organic bases represented by formula (II) wherein B.sup.+ is either an alkaline metal cation, alkaline earth metal cation, cyclohexylamine cation, or lysine cation. Said substances are characterized by antiinflamatory properties comparable to (and greater than) the initial acid while simultaneously said modifications of their physico-chemical properties broaden the posibilities of their therapeutic application.
    Type: Grant
    Filed: June 17, 1991
    Date of Patent: January 5, 1993
    Assignee: Vyzkumng, USTAV pro farmacii a biochemii, Statni podnik
    Inventors: Miroslav Kuchar, Marie Poppova, Jaroslava Grimova, Eva Maturova
  • Patent number: 4973691
    Abstract: An etheric derivative of 4(3H)-quinazolinone which is a fluorinated 3-[2-(4-biphenylyloxy)ethyl]-4(3H)-quinazolinone, produced by reacting said 4(3H)-quinazolinone with the corresponding fluorinated 4-(2-chloroethoxy)biphenyl, and its acid addition salts, especially the hydrochloride. This compound possesses substantially higher analgesic activity and lower acute toxicity than aminophenazone, ibuprofen, acetylosalicyclic acid and paracetamol.
    Type: Grant
    Filed: November 1, 1989
    Date of Patent: November 27, 1990
    Assignee: Spojene Podniky Prozdravotnickou Vyrobu (SPOFA)
    Inventors: Ludmila Fisnerova, Bohumila Brunova, Eva Maturova, Jaroslava Grimova
  • Patent number: 4683331
    Abstract: The invention relates to omega-(2',4'-dihalobiphenylyl)oxo alkanoic acids of Formula: ##STR1## wherein X.sup.1 and X.sup.2 each represent a fluorine or chlorine atom and Y represents a bivalent hydrocarbon chain selected from the group consisting of --CH.sub.2 --CH--CH.sub.3 and (CH.sub.2).sub.3, and to a process for their preparation.The compounds of the invention are highly active and longlasting anti-inflammatory agents.
    Type: Grant
    Filed: July 29, 1985
    Date of Patent: July 28, 1987
    Assignee: Spofa spojene podniky pro zdravotnickou
    Inventors: Miroslav Kuchar, Bohumila Brunova, Jaroslava Grimova, Eva Maturova