Patents by Inventor Eva WULSTEN

Eva WULSTEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aqueous pharmaceutical formulation of tapentadol for oral administration
    Patent number: 11547678
    Abstract: An aqueous pharmaceutical composition containing tapentadol or a physiologically acceptable salt thereof and being adapted for oral administration. The composition has excellent storage stability without relying on the presence of high amounts of preservatives.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: January 10, 2023
    Assignee: Gruenenthal GmbH
    Inventors: Ulrich Reinhold, Marc Schiller, Eva Wulsten, Sabine Karine Katrien Inghelbrecht, Roger Carolus Augusta Embrechts, Ulrich Feil
  • Stable formulation for parenteral administration of tapentadol
    Patent number: 11013701
    Abstract: The invention relates to an aqueous pharmaceutical composition for parenteral administration comprising Tapentadol or a physiologically acceptable salt thereof, wherein the concentration of Tapentadol is within the range of from 0.10 to 8.00 mg/mL, based on the weight of Tapentadol free base and based on the total volume of the composition; and wherein the pH value of the composition is buffered and within the range of from 4.0 to 6.0. The invention also relates to a container comprising the pharmaceutical composition and a process for the preparation thereof. The invention also relates to a kit comprising the contained according to the invention in a packaging. The pharmaceutical composition according to the invention is particularly useful for treating pain, especially acute pain, preferably in pediatric patients.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: May 25, 2021
    Assignee: Grünenthal GmbH
    Inventors: Marc Schiller, Carlos van Hemelrijck, Stefanie Straub, Eva Wulsten, Ulrike Bertram, Ulrich Reinhold
  • PARENTERAL ADMINISTRATION OF TAPENTADOL
    Publication number: 20200215003
    Abstract: An aqueous pharmaceutical composition adapted for parenteral administration of tapentadol or a physiologically acceptable salt thereof having a pH value of at least 5.4.
    Type: Application
    Filed: March 13, 2020
    Publication date: July 9, 2020
    Applicant: GRÜNENTHAL GMBH
    Inventors: Thomas CHRISTOPH, Sabine Karine Katrien INGHELBRECHT, Roger Carolus Augusta EMBRECHTS, Ulrich REINHOLD, Marc SCHILLER, Eva WULSTEN, Petra BLOMS-FUNKE, Klaus SCHIENE, Ulrich FEIL
  • AQUEOUS PHARMACEUTICAL FORMULATION OF TAPENTADOL FOR ORAL ADMINISTRATION
    Publication number: 20200054584
    Abstract: An aqueous pharmaceutical composition containing tapentadol or a physiologically acceptable salt thereof and being adapted for oral administration. The composition has excellent storage stability without relying on the presence of high amounts of preservatives.
    Type: Application
    Filed: October 24, 2019
    Publication date: February 20, 2020
    Applicant: GRÜNENTHAN GMBH
    Inventors: Ulrich REINHOLD, Marc SCHILLER, Eva WULSTEN, Sabine Karine Katrien INGHELBRECHT, Roger Carolus Augusta EMBRECHTS, Ulrich FEIL
  • Semisolid Aqueous Pharmaceutical Composition Containing Tapentadol
    Publication number: 20180133174
    Abstract: A semisolid aqueous pharmaceutical composition containing tapentadol or a physiologically acceptable salt thereof.
    Type: Application
    Filed: January 10, 2018
    Publication date: May 17, 2018
    Inventors: Ulrich REINHOLD, Marc SCHILLER, Eva WULSTEN, Sabine Karine Katrien INGHELBRECHT, Roger Carolus Augusta EMBRECHTS, Ulrich FEIL
  • Stable Formulation for Parenteral Administration of Tapentadol
    Publication number: 20180125800
    Abstract: The invention relates to an aqueous pharmaceutical composition for parenteral administration comprising Tapentadol or a physiologically acceptable salt thereof, wherein the concentration of Tapentadol is within the range of from 0.10 to 8.00 mg/mL, based on the weight of Tapentadol free base and based on the total volume of the composition; and wherein the pH value of the composition is buffered and within the range of from 4.0 to 6.0. The invention also relates to a container comprising the pharmaceutical composition and a process for the preparation thereof. The invention also relates to a kit comprising the contained according to the invention in a packaging. The pharmaceutical composition according to the invention is particularly useful for treating pain, especially acute pain, preferably in pediatric patients.
    Type: Application
    Filed: January 10, 2018
    Publication date: May 10, 2018
    Inventors: Marc SCHILLER, Carlos van Hemelrijck, Stefanie STRAUB, Eva WULSTEN, Ulrike BERTRAM, Ulrich REINHOLD
  • Semisolid Aqueous Pharmaceutical Composition Containing Tapentadol
    Publication number: 20160346229
    Abstract: A semisolid aqueous pharmaceutical composition containing tapentadol or a physiologically acceptable salt thereof.
    Type: Application
    Filed: August 10, 2016
    Publication date: December 1, 2016
    Inventors: Ulrich REINHOLD, Marc SCHILLER, Eva WULSTEN, Sabine Karine Katrien INGHELBRECHT, Roger Carolus Augusta EMBRECHTS, Ulrich FEIL
  • Stable Formulation for Parenteral Administration of Tapentadol
    Publication number: 20160279078
    Abstract: The invention relates to an aqueous pharmaceutical composition for parenteral administration comprising Tapentadol or a physiologically acceptable salt thereof, wherein the concentration of Tapentadol is within the range of from 0.10 to 8.00 mg/mL, based on the weight of Tapentadol free base and based on the total volume of the composition; and wherein the pH value of the composition is buffered and within the range of from 4.0 to 6.0. The invention also relates to a container comprising the pharmaceutical composition and a process for the preparation thereof. The invention also relates to a kit comprising the contained according to the invention in a packaging. The pharmaceutical composition according to the invention is particularly useful for treating pain, especially acute pain, preferably in pediatric patients.
    Type: Application
    Filed: March 23, 2016
    Publication date: September 29, 2016
    Inventors: Marc SCHILLER, Carlos van Hemelrijck, Stefanie STRAUB, Eva WULSTEN, Ulrike BERTRAM, Ulrich REINHOLD
  • Semisolid aqueous pharmaceutical composition containing tapentadol
    Patent number: 9446008
    Abstract: A semisolid aqueous pharmaceutical composition containing tapentadol or a physiologically acceptable salt thereof.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: September 20, 2016
    Assignee: Gruenenthal GmbH
    Inventors: Ulrich Reinhold, Marc Schiller, Eva Wulsten, Sabine Karine Katrien Inghelbrecht, Roger Carolus Augusta Embrechts, Ulrich Feil
  • Aqueous Pharmaceutical Formulation of Tapentadol for Oral Administration
    Publication number: 20160220516
    Abstract: An aqueous pharmaceutical composition containing tapentadol or a physiologically acceptable salt thereof and being adapted for oral administration. The composition has excellent storage stability without relying on the presence of high amounts of preservatives.
    Type: Application
    Filed: April 7, 2016
    Publication date: August 4, 2016
    Inventors: Ulrich REINHOLD, Marc SCHILLER, Eva WULSTEN, Sabine Karine Katrien INGHELBRECHT, Roger Carolus Augusta EMBRECHTS, Ulrich FEIL
  • Parenteral Administration of Tapentadol
    Publication number: 20160106688
    Abstract: An aqueous pharmaceutical composition adapted for parenteral administration of tapentadol or a physiologically acceptable salt thereof having a pH value of at least 5.4.
    Type: Application
    Filed: December 28, 2015
    Publication date: April 21, 2016
    Inventors: Thomas CHRISTOPH, Sabine Karine Katrien INGHELBRECHT, Roger Carolus Augusta EMBRECHTS, Ulrich REINHOLD, Marc SCHILLER, Eva WULSTEN, Petra BLOMS-FUNKE, Klaus SCHIENE, Ulrich FEIL
  • Aqueous Pharmaceutical Formulation of Tapentadol for Oral Administration
    Publication number: 20130022670
    Abstract: An aqueous pharmaceutical composition containing tapentadol or a physiologically acceptable salt thereof and being adapted for oral administration. The composition has excellent storage stability without relying on the presence of high amounts of preservatives.
    Type: Application
    Filed: March 2, 2012
    Publication date: January 24, 2013
    Applicant: Gruenenthal GmbH
    Inventors: Ulrich REINHOLD, Marc Schiller, Eva Wulsten, Sabine Karine Katrien Inghelbrecht, Roger Carolus Augusta Embrechts
  • Semisolid Aqueous Pharmaceutical Composition Containing Tapentadol
    Publication number: 20120225950
    Abstract: A semisolid aqueous pharmaceutical composition containing tapentadol or a physiologically acceptable salt thereof.
    Type: Application
    Filed: March 2, 2012
    Publication date: September 6, 2012
    Applicant: Gruenenthal GmbH
    Inventors: Ulrich REINHOLD, Marc SCHILLER, Eva WULSTEN, Sabine Karine Katrien INGHELBRECHT, Roger Carolus Augusta EMBRECHTS