Patents by Inventor Evan D. SHAPIRO
Evan D. SHAPIRO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11766038Abstract: An apparatus for perfusing an organ or tissue includes a perfusion circuit for perfusing the organ or tissue; an oxygenator for oxygenating perfusate that circulates through the perfusion circuit; and an oxygen supply device such as an oxygen concentrator or an oxygen generator configured to supply oxygen to the oxygenator. A method of perfusing an organ or tissue includes producing oxygen from a device such as an oxygen concentrator and an oxygen generator; supplying the produced oxygen, preferably as the oxygen is produced, to a perfusate to oxygenate the perfusate; and perfusing the organ or tissue with the oxygenated perfusate. The produced oxygen preferably has a concentration greater than the oxygen concentration in air.Type: GrantFiled: December 10, 2015Date of Patent: September 26, 2023Assignee: LIFELINE SCIENTIFIC, INC.Inventors: Christopher P. Steinman, David Kravitz, Aaron R. Ferber, Ross Lockwood, Rodney H. Monson, Evan D. Shapiro
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Patent number: 9968082Abstract: A method of perfusing an organ or tissue includes perfusing the organ or tissue with a perfusion apparatus; detecting a condition representing at least one of an attitude of the perfusion apparatus or at least one shock experienced by the perfusion apparatus; and altering perfusion based upon the detected condition and/or recording the detected condition.Type: GrantFiled: August 31, 2015Date of Patent: May 15, 2018Assignee: LIFELINE SCIENTIFIC, INC.Inventors: Christopher P. Steinman, John Stark, Joel C. Hagen, Aaron R. Ferber, Rodney H. Monson, Evan D. Shapiro
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Patent number: 9565853Abstract: An apparatus for separating gas bubbles that may be entrained in perfusate flow prevents such bubbles from continuing downstream and entering an organ or tissue. The apparatus may include a chamber having a top wall, a bottom wall and side walls. The chamber may include an inlet configured to allow at least one of gas and liquid to enter the chamber, an air opening configured to allow at least gas to exit the chamber and a first liquid opening configured to allow at least liquid to exit the chamber. The apparatus may function as an accumulator that reduces or eliminates pulsatility of the liquid flow and pressure. The apparatus may include a minimum volume of gas, initially or through the accumulation of gas, such that flow and pressure fluctuations in the liquid are dampened or eliminated. The apparatus may include a sampling port in a wall of the chamber.Type: GrantFiled: July 10, 2012Date of Patent: February 14, 2017Assignee: LIFELINE SCIENTIFIC, INC.Inventors: Christopher P. Steinman, Jeffrey S. Louis, Rick W. Walker, Evan D. Shapiro, Aaron R. Ferber, Rodney H. Monson, John Stark, Ross Lockwood
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Publication number: 20160088834Abstract: An apparatus for perfusing an organ or tissue includes a perfusion circuit for perfusing the organ or tissue; an oxygenator for oxygenating perfusate that circulates through the perfusion circuit; and an oxygen supply device such as an oxygen concentrator or an oxygen generator configured to supply oxygen to the oxygenator. A method of perfusing an organ or tissue includes producing oxygen from a device such as an oxygen concentrator and an oxygen generator; supplying the produced oxygen, preferably as the oxygen is produced, to a perfusate to oxygenate the perfusate; and perfusing the organ or tissue with the oxygenated perfusate. The produced oxygen preferably has a concentration greater than the oxygen concentration in air.Type: ApplicationFiled: December 10, 2015Publication date: March 31, 2016Applicant: LIFELINE SCIENTIFIC, INC.Inventors: Christopher P. STEINMAN, David KRAVITZ, Aaron R. FERBER, Ross LOCKWOOD, Rodney H. MONSON, Evan D. SHAPIRO
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Publication number: 20150366183Abstract: A method of perfusing an organ or tissue includes perfusing the organ or tissue with a perfusion apparatus; detecting a condition representing at least one of an attitude of the perfusion apparatus or at least one shock experienced by the perfusion apparatus; and altering perfusion based upon the detected condition and/or recording the detected condition.Type: ApplicationFiled: August 31, 2015Publication date: December 24, 2015Inventors: Christopher P. STEINMAN, John STARK, Joel C. HAGEN, Aaron R. FERBER, Rodney H. MONSON, Evan D. SHAPIRO
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Patent number: 9119393Abstract: An apparatus for perfusing an organ or tissue includes a perfusion circuit configured to perfuse the organ or tissue; at least one shock and/or tilt detector such as an accelerometer; and a controller. The controller may be configured to control perfusion based upon a signal received from the accelerometer, which may include stopping and/or starting the perfusion based upon the signal. The controller may also or alternatively sense and/or record shocks experienced by the apparatus.Type: GrantFiled: July 10, 2012Date of Patent: September 1, 2015Assignee: LIFELINE SCIENTIFIC, INC.Inventors: Christopher P. Steinman, John Stark, Joel C. Hagan, Aaron R. Ferber, Rodney H. Monson, Evan D. Shapiro
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Publication number: 20140017658Abstract: An apparatus for separating gas bubbles that may be entrained in perfusate flow prevents such bubbles from continuing downstream and entering an organ or tissue. The apparatus may include a chamber having a top wall, a bottom wall and side walls. The chamber may include an inlet configured to allow at least one of gas and liquid to enter the chamber, an air opening configured to allow at least gas to exit the chamber and a first liquid opening configured to allow at least liquid to exit the chamber. The apparatus may function as an accumulator that reduces or eliminates pulsatility of the liquid flow and pressure. The apparatus may include a minimum volume of gas, initially or through the accumulation of gas, such that flow and pressure fluctuations in the liquid are dampened or eliminated. The apparatus may include a sampling port in a wall of the chamber.Type: ApplicationFiled: July 10, 2012Publication date: January 16, 2014Applicant: LIFELINE SCIENTIFIC, INC.Inventors: Christopher P. STEINMAN, Jeffrey S. LOUIS, Rick W. WALKER, Evan D. SHAPIRO, Aaron R. FERBER, Rodney H. MONSON, John STARK, Ross LOCKWOOD
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Publication number: 20140017663Abstract: An apparatus for perfusing an organ or tissue includes a perfusion circuit configured to perfuse the organ or tissue; at least one shock and/or tilt detector such as an accelerometer; and a controller. The controller may be configured to control perfusion based upon a signal received from the accelerometer, which may include stopping and/or starting the perfusion based upon the signal. The controller may also or alternatively sense and/or record shocks experienced by the apparatus.Type: ApplicationFiled: July 10, 2012Publication date: January 16, 2014Applicant: LIFELINE SCIENTIFIC, INC.Inventors: Christopher P. STEINMAN, John STARK, Joel C. HAGAN, Aaron R. FERBER, Rodney H. MONSON, Evan D. SHAPIRO
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Publication number: 20140017665Abstract: An apparatus for perfusing an organ or tissue includes a perfusion circuit for perfusing the organ or tissue; an oxygenator for oxygenating perfusate that circulates through the perfusion circuit; and an oxygen supply device such as an oxygen concentrator or an oxygen generator configured to supply oxygen to the oxygenator. A method of perfusing an organ or tissue includes producing oxygen from a device such as an oxygen concentrator and an oxygen generator; supplying the produced oxygen, preferably as the oxygen is produced, to a perfusate to oxygenate the perfusate; and perfusing the organ or tissue with the oxygenated perfusate. The produced oxygen preferably has a concentration greater than the oxygen concentration in air.Type: ApplicationFiled: July 10, 2012Publication date: January 16, 2014Applicant: LIFELINE SCIENTIFIC, INC.Inventors: Christopher P. STEINMAN, David KRAVITZ, Aaron R. FERBER, Ross LOCKWOOD, Rodney H. MONSON, Evan D. SHAPIRO