Patents by Inventor Evan E. Shave

Evan E. Shave has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • WATER-SOLUBLE, UV-ABSORBING AND/OR FLOURESCENT COMPONENTS WITH VERY HIGH ISOELECTRIC POINTS
    Publication number: 20150136603
    Abstract: Water-soluble, UV-absorbing and/or fluorescing compound having an isoelectric point greater than 10, can be obtained using molecules chosen from the group of molecules consisting of those containing at least one secondary alcohol OH group with a pKa value greater than 10 and at least one amino group with a pKb value smaller than 5, those containing at least one primary alcohol OH group and at least one secondary alcohol OH group with respective pKa values greater than 10 and at least one amino el group with a pKb value smaller than 5 or a quaternary ammonium group, and those containing at least two secondary alcohol OH groups with respective pKb values greater than 10 and at least one amino group with a pKb value smaller than 5 or a quaternary ammonium group; and having at least one UV absorbing group or at least one fluorescing group or a combination thereof. The invention includes methods for producing such compounds.
    Type: Application
    Filed: December 31, 2014
    Publication date: May 21, 2015
    Inventors: Gyula Vigh, Sanjiv K. Lalwani, Brent Busby, Kingsley Nzeadibo, Helen C. Fleisher, Evan E. Shave
  • Apo-2 ligand/trail formulations
    Patent number: 8470969
    Abstract: The present invention relates generally to Apo2L/TRAIL purification involving crystallization.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: June 25, 2013
    Assignee: Genentech, Inc.
    Inventors: Heather Flores, Tanya P. Lin, Timothy C. Matthews, Roger Pai, Zahra Shahrokh, Evan E. Shave, Patricia A. Rancatore
  • APO-2 LIGAND/TRAIL FORMULATIONS
    Publication number: 20110269947
    Abstract: The present invention relates generally to Apo2L/TRAIL purification involving crystallization.
    Type: Application
    Filed: June 23, 2010
    Publication date: November 3, 2011
    Inventors: Heather Flores, Tanya P. Lin, Timothy C. Matthews, Roger Pai, Zahra Shahrokh, Evan E. Shave, Patricia A. Rancatore
  • Water-soluble, uv-absorbing and/or flourescent components with very high isoelectric points
    Publication number: 20090023912
    Abstract: Water-soluble, UV-absorbing and/or fluorescing compound having an isoelectric point greater than 10, can be obtained using molecules chosen from the group of molecules consisting of those containing at least one secondary alcohol OH group with a PKa value greater than 10 and at least one amino group with a pKb value smaller than 5, those containing at least one primary alcohol OH group and at least one secondary alcohol OH group with respective PKa values greater than 10 and at least one amino group with a pKb value smaller than 5 or a quaternary ammonium group, and those containing at least two secondary alcohol OH groups with respective pKa values greater than 10 and at least one amno group with a pKb value smaller than 5 or a quaternary ammonium group; and having at least one UV absorbing group or at least one fluorescing group or a combination thereof. The invention includes methods for producing such compounds.
    Type: Application
    Filed: April 22, 2005
    Publication date: January 22, 2009
    Inventors: Gyula Vigh, Sanjiv K. Lalwani, Brent Busby, Kingsley Nzeadibe, Helen C. Fleisher, Evan E. Shave