Abstract: The present disclosure relates to certain macrocyclic compounds that inhibit SRC and MET, and/or CSF1R, pharmaceutical compositions containing such compounds, and methods of using such compounds to treat cancer.

Abstract: A computer-implemented method includes receiving a document insight request that requests document insights for a corpus of documents. The document insight request includes the corpus of documents, a set of entities contained within each document of the corpus of documents, and document insight request parameters that includes a confidence value threshold. The method also includes generating the document insights for the corpus of documents based on the confidence value threshold. Here, the document insights include an accuracy target and a user review rate target. The method also includes transmitting the document insights to the user device causing a graphical user interface to display the document insights on the user device.

Abstract: The present invention provides methods and apparatuses that utilize a portable apparatus to securely operate a host electronic device. Typically, each portable apparatus includes a data storage unit which stores an operating system and other software. In one example, a portable apparatus can provide a virtual operating environment on top of a host's operating system for a host device. In another example, a portable apparatus containing its operating system can directly boot a host device with one or more hardware profiles. Furthermore, a device-dependent protection against software piracy, a user-dependent protection against sensitive data leaks, a controllable host operating environment to prevent unwanted information exposure, and a secure restoration procedure to prevent virus infection between the host device users may be incorporated. Moreover, a pre-defined information may also be utilized to authorize a connected-state guest operation environment in the host device.

Abstract: The present invention provides methods and apparatus that utilize a portable apparatus to operate a host computer. The portable apparatus including an operating system and a list of software applications is installed in a removable data storage medium. The basic input/output system (BIOS) of the host computer will directly or indirectly identify the portable apparatus as its boot drive. The host computer will further load the operating system in the portable apparatus into its random access semiconductor memory (RAM). A hardware profile is stored in the host computer, which contains information about the host computer and its peripheral devices. During the loading, the operating system will incorporate information in the hardware profile in order to fully operate the host computer and the hardware devices defined in the profile.