Patents by Inventor Evan M. Jones

Evan M. Jones has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glycosylated peptides with pseudoproline residues and having enhanced half-lives and ability to cross the blood brain barrier
    Patent number: 10858410
    Abstract: Glycosylated peptides with glycosylation at or near the C-terminal domain of the peptide have an enhanced ability to cross the blood brain barrier (BBB) and/or enhanced half-lives. These glycosylated peptides may be used as drugs. For example, a PACAP peptide with a C-terminal glycosylation, e.g., in lieu of the terminal leucine, functions as a PAC1 agonist with enhanced ability to cross the BBB and with enhanced half-life. The peptides can have a pseudoproline residue with glycosylation at or near the C-terminal domain.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: December 8, 2020
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventors: Robin Polt, Evan M. Jones, Bobbi Anglin, Michael L. Heien, John M. Streicher
  • GLYCOSYLATED PEPTIDES WITH PSEUDOPROLINE RESIDUES AND HAVING ENHANCED HALF-LIVES AND ABILITY TO CROSS THE BLOOD BRAIN BARRIER
    Publication number: 20200270318
    Abstract: Glycosylated peptides with glycosyiatiou at or near the C-terminal domain of the peptide have an enhanced ability to cross the blood brain barrier (BBB) and/or enhanced half-lives. These glycosylated peptides may be used as drugs. For example, a PACAP peptide with a C-terminal glycosylation, e.g., in lieu of the terminal leucine, functions as a PAC1 agonist with enhanced ability to cross the BBB and with enhanced half-life. The peptides can have a pseudoproline residue with glycosylation at or near the C-terminal domain.
    Type: Application
    Filed: August 12, 2016
    Publication date: August 27, 2020
    Inventors: Robin Polt, Evan M. Jones, Bobbi Anglin, Michael L. Heien, John M. Streicher