Patents by Inventor Evan M. McIntosh

Evan M. McIntosh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High-throughput screens for enzyme inhibitors
    Patent number: 6322991
    Abstract: The present invention provides a high-throughput screen for use in assaying for enzyme inhibitors of a target organism, comprising: a microorganism host in which an endogenous enzyme encoding gene has been replaced by a functionally complementing enzyme encoding gene from the target organism. The present invention also provides a method of identifying an inhibitor of a target organism enzyme, comprising the step of assaying a test inhibitor using a high-throughput screen comprising a microorganism host in which an endogenous enzyme encoding gene has been replaced by a functionally complementing enzyme encoding gene from the target organism.
    Type: Grant
    Filed: August 20, 1998
    Date of Patent: November 27, 2001
    Assignee: York University
    Inventors: Ronald E. Pearlman, Leroi DeSouza, J. Bryan McNeil, Evan M. McIntosh