Patents by Inventor Evan Samuel Deneris

Evan Samuel Deneris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neuronal nicotinic acetylcholine receptor compositions
    Patent number: 6967244
    Abstract: The present invention relates to a family of neuronal nicotinic acetylcholine receptors comprised of neuronal agonist and non-agonist binding subunits, and DNA sequences encoding such subunits. These novel neuronal nicotinic acetylcholine receptor subunits include the agonist binding subunits alpha2, alpha3, alpha4, and alpha5, plus non-agonist binding subunits beta2, beta3 and beta4. Representative cDNA clones that contain the DNA sequences of the invention have been deposited with the American Type Culture Collection for patent purposes.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: November 22, 2005
    Assignee: The Salk Institute for Biological Studies
    Inventors: Stephen Fox Heinemann, James Warner Patrick, James Richard Boulter, Evan Samuel Deneris, Keiji Wada, Marc Charles Ballivet, Daniel Jay Goldman, John Gerard Connolly, Robert Michael Duvoisin, Eden Deer Heinemann
  • Reagents and methods for the screening of compounds useful in the treatment of neurological diseases
    Publication number: 20030175830
    Abstract: This invention relates to the gene sequence of a novel transcription factor specific for central 5-HT (serotonergic) neurons. The sequence and products are useful in screening methods for identifying and testing agonists and antagonists of seronergic activity.
    Type: Application
    Filed: October 25, 2001
    Publication date: September 18, 2003
    Applicant: Case Western Reserve University
    Inventors: Evan Samuel Deneris, Timothy John Hendricks, Dmitry Viktor Fyodorov
  • Reagents and methods for the screening of compounds useful in the treatment of neurological diseases
    Publication number: 20020090647
    Abstract: This invention relates to the gene sequence of a novel transcription factor specific for central 5-HT (serotonergic) neurons. The sequence and products are useful in screening methods for identifying and testing agonists and antagonists of seronergic activity.
    Type: Application
    Filed: May 8, 2001
    Publication date: July 11, 2002
    Applicant: Case Western Reserve University
    Inventors: Evan Samuel Deneris, Dmitry Viktor Fyodorov, Timothy John Hendricks
  • Reagents and methods for the screening of compounds useful in the treatment of neurological diseases
    Patent number: 6384204
    Abstract: This invention relates to the gene sequence of a novel transcription factor specific for central 5-HT (serotonergic) neurons. The sequence and products are useful in screening methods for identifying and testing agonists and antagonists of seronergic activity.
    Type: Grant
    Filed: November 5, 1999
    Date of Patent: May 7, 2002
    Inventors: Evan Samuel Deneris, Dmitry Viktor Fyodorov, Timothy John Hendricks
  • Reagents and methods for the screening of compounds useful in the treatment of neurological diseases
    Patent number: 6268216
    Abstract: This invention relates to the gene sequence of a novel transcription factor specific for central 5-HT (serotonergic) neurons. The sequence and products are useful in screening methods for identifying and testing agonists and antagonists of seronergic activity.
    Type: Grant
    Filed: July 26, 1999
    Date of Patent: July 31, 2001
    Assignee: Case Western Reserve University
    Inventors: Evan Samuel Deneris, Dmitry Viktor Fyodorov, Timothy John Hendricks
  • Neuronal nicotinic acetylcholihne receptor compositions
    Patent number: 6136550
    Abstract: The present invention relates to a family of neuronal nicotinic acetylcholine receptors comprised of neuronal agonist and non-agonist binding subunits, and DNA sequences encoding such subunits. These novel neuronal nicotinic acetylcholine receptor subunits include the agonist binding subunits alpha2, alpha3, alpha4, and alpha5, plus non-agonist binding subunits beta2, beta3 and beta4. Representative cDNA clones that contain the DNA sequences of the invention have been deposited with the American Type Culture Collection for patent purposes.
    Type: Grant
    Filed: December 6, 1994
    Date of Patent: October 24, 2000
    Assignee: The Salk Institute for Biological Studies
    Inventors: Stephen Fox Heinemann, James Warner Patrick, James Richard Boulter, Evan Samuel Deneris, Keiji Wada, Marc Charles Ballivet, Daniel Jay Goldman, John Gerard Connolly, Robert Michael Duvoisin, Eden Deer Heinemann
  • Recombinantly produced .beta.4 neuronal nicotinic acetylcholine receptor subunits
    Patent number: 5789196
    Abstract: The present invention discloses a new neuronal nicotinic acetylcholine receptor subunit, .beta.4. The new subunit can form functional combinations with other neuronal nicotinic acetylcholine receptor subunits, including, but not limited to, alpha2, alpha3, alpha4 and beta2. A cDNA clone containing the DNA sequences that encode the novel receptor subunit of the invention has been deposited with the American Type Culture Collection for patent purposes.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 4, 1998
    Inventors: Stephen Fox Heinemann, Robert Michael Duvoisin, Evan Samuel Deneris, James Warner Patrick