Abstract: The present invention provides for delivery of therapeutic drug in a polymeric delivery system comprising a PEG-bl-PPS di-block polymer formed in a micelle, filomicelle, or polymersome structure, wherein the structure effectively binds and/or interacts through shape-based targeting with a targeted cell type.

Abstract: An automated collectible card grading system includes a memory, a communication interface and a processor configured to execute instructions that include receiving a target image of a collectible card depicting a subject, isolating spatial features of the target image, generating a card feature model, applying the card feature model to the isolated spatial features to create a plurality of card metrics, and creating a grade report for the collectible card based on the card metrics. The card feature model is generated using a deep learning algorithm trained using other images of other collectible cards that are also isolated into spatial features. Isolated special features can include corners, edge regions, central regions, and surface impressions. The graded collectible card subject is a specific collectible card representation created by a collectible card manufacturer and can be different than the subjects of the other collectible cards used by the card feature model.

Abstract: The present invention provides for delivery of therapeutic drug in a polymeric delivery system comprising a PEG-bl-PPS di-block polymer formed in a micelle, filomicelle, or polymersome structure, wherein the structure effectively binds and/or interacts through shape-based targeting with a targeted cell type.

Abstract: The invention generally relates to surfaces having a protein-resistant hydrogel layer and methods for preparing a protein-resistant hydrogel layer on a surface. The protein-resistant hydrogel layer is formed by a protein-crosslinked water soluble polymer that is contacted with a surface to form a thin protein-resistant hydrogel layer on the surface.

Abstract: The invention generally relates to substrates and surfaces having substrates. Generally speaking, the substrates may be thinly layered substrates, and the surfaces may comprise thinly layered substrates. Additionally, the substrates may comprise a multifunctional water soluble polymer and a lipoprotein and the surfaces may comprise a multifunctional water soluble polymer and a lipoprotein.

Abstract: The invention generally relates to substrates and surfaces having substrates. Generally speaking, the substrates may be thinly layered substrates, and the surfaces may comprise thinly layered substrates. Additionally, the substrates may comprise a multifunctional water soluble polymer and a lipoprotein and the surfaces may comprise a multifunctional water soluble polymer and a lipoprotein.