Patents by Inventor Evan T. Keller

Evan T. Keller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for detecting cancer and for inhibiting metastasis
    Patent number: 7641902
    Abstract: The present invention relates to compositions and methods for detecting cancer (e.g., prostate cancer) and for inhibiting metastasis (e.g., associated with prostate cancer). In particular, the present invention provides methods of detecting vimentin expression and secretion and for characterizing cancer (e.g., prostate cancer). In addition, the present invention provides methods for inhibiting metastasis (e.g., of prostate cancer) via altering (e.g., inhibiting) vimentin expression and/or activity.
    Type: Grant
    Filed: November 20, 2006
    Date of Patent: January 5, 2010
    Assignee: The Regents of the University of Michigan
    Inventors: David M. Markovitz, Nirit Mor-Vaknin, Evan T. Keller, Christopher L. Hall, Susan M. Hiniker
  • shRNA Materials and Methods of Using Same for Inhibition of DKK-1
    Publication number: 20080293053
    Abstract: Methods and compositions for the treatment of soft tissue cancer are described. More specifically, the invention demonstrates that inhibiting or otherwise decreasing the activity of DKK-1 using shRNA or siRNA molecules will be effective at reducing the cancer phenotype of prostate cancer cells.
    Type: Application
    Filed: December 28, 2007
    Publication date: November 27, 2008
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Evan T. Keller, Christopher L. Hall, Stuart A. Aaronson
  • Systems and methods for detecting and regulating metastasis
    Patent number: 7407763
    Abstract: The present invention relates to compositions and methods for cancer diagnostics and therapeutics, including but not limited to, RKIP cancer markers and RKIP pathway modulators. In particular, the present invention provides compositions and methods of using RKIP in the diagnosis and treatment of prostate cancers.
    Type: Grant
    Filed: February 7, 2005
    Date of Patent: August 5, 2008
    Assignee: The Regents of the University of Michigan
    Inventors: Evan T. Keller, Zheng Fu