Abstract: Methods are disclosed herein for at least one of (i) substantially reducing Plasmodium and/or oocyst development, (ii) substantially reducing mating success, (iii) substantially abolishing egg development after blood feeding, (iv) substantially reducing the mean survival rate; (v) substantially reducing at least one of the transmission of mosquito borne pathogens; and (vi) substantially reducing the propensity for mosquito biting comprising contacting adult, female mosquitoes with a composition comprising an effective amount of one or more non-steroidal ecdysone agonists. The one or more non-steroidal ecdysone agonists can be comprised indoor or outdoor surface.