Patents by Inventor Evelyn Sabrinah Chapman

Evelyn Sabrinah Chapman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Highly sensitive, accurate, and precise automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
    Patent number: 6025201
    Abstract: The present invention provides a highly sensitive and accurate method and system for the discrimination and quantification of platelets in a whole blood sample using automated hematology instruments. The method and system of the invention provide the accurate measurements of platelet dry mass and platelet component concentration in both normal blood samples and in abnormal blood samples, such as those from thrombocytopenic patients. The determination of platelet dry mass and platelet component concentration can serve to assess the activation state of platelets since activated platelets possess measurably lower component concentrations and refractive indices than do non-activated platelets. The method and system of the invention also allows the clinician or skilled practitioner to determine the age of a blood sample on the basis of the measured parameter of platelet component concentration.
    Type: Grant
    Filed: June 27, 1997
    Date of Patent: February 15, 2000
    Assignee: Bayer Corporation
    Inventors: David Zelmanovic, Gregory M. Colella, Edward J. Hetherington, Evelyn Sabrinah Chapman, Lynn Paseltiner
  • Automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
    Patent number: 5817519
    Abstract: The present invention provides a highly sensitive and accurate method and system for the discrimination and quantification of platelets in a whole blood sample using automated hematology instruments. The method and system of the invention provide the accurate measurements of platelet dry mass and platelet component concentration in both normal blood samples and in abnormal blood samples, such as those from thrombocytopenic patients. The determination of platelet dry mass and platelet component concentration can serve to assess the activation state of platelets since activated platelets possess measurably lower component concentrations and refractive indices than do unactivated platelets. The method and system of the invention also allows the clinician or skilled practitioner to determine the age of a blood sample on the basis of the measured parameter of platelet component concentration.
    Type: Grant
    Filed: November 1, 1996
    Date of Patent: October 6, 1998
    Assignee: Bayer Corporation
    Inventors: David Zelmanovic, Gregory M. Colella, Edward J. Hetherington, Evelyn Sabrinah Chapman, Lynn Paseltiner