Abstract: Methods and antibody compositions that displace mannose from the binding pocket of fimbrial adhesin FimH of enterobacteria, including uropathogenic E. coli, Klebsiella oxytoca, or Klebsiella pneumoniae, can be used to disrupt or prevent the attachment of a single layer of bacteria to a mannose-coated surface, or to disrupt or prevent the formation of a multilayer biofilm. The antibody compositions of the invention can thus be used in methods to inhibit, prevent, or reverse the colonization of a surface with enterobacteria that express the bacterial Type 1 fimbrial adhesin FimH, to inhibit or prevent infection of a cell by enterobacteria that express the bacterial Type 1 fimbrial adhesin FimH, such as, for example, uropathogenic E. coli, to treat a bacterial infection in subject in need thereof and to treat or prevent inflammatory bowel disease (IBD), among other uses.

Abstract: An accessory apparatus includes a housing, an apparatus connector, a plurality of auxiliary accessory interfaces, and an internal microcontroller. The connection connector is configured to mate with a corresponding accessory connector of a physical controller to electrically connect the internal microcontroller to the physical controller. Each auxiliary accessory connector is configured to enable a separate auxiliary user input device to operatively connect to the accessory apparatus and electrically connect with the internal microcontroller. The internal microcontroller is configured to: (1) receive an input control signal from an auxiliary user input device operatively connected to an auxiliary accessory connector of the plurality of auxiliary accessory connectors, (2) map the input control signal to a mapped control signal corresponding to a physical control of the physical controller, and (3) send the mapped control signal to the physical controller via the apparatus connector.

Abstract: A method for fusing game control inputs includes, on a computing device, receiving a first game control input from a first input device having a first housing and receiving a second game control input from a second input device having a second housing. The first game and second game control inputs are fused into a fused game control input mimicking a game control input from a single input device having a single housing. The fused game control input is provided to a video game application.

Abstract: A method for fusing game control inputs includes, on a computing device, receiving a first game control input from a first input device having a first housing and receiving a second game control input from a second input device having a second housing. The first game and second game control inputs are fused into a fused game control input mimicking a game control input from a single input device having a single housing. The fused game control input is provided to a video game application.

Abstract: Methods and antibody compositions that displace mannose from the binding pocket of fimbrial adhesin FimH of enterobacteria, including uropathogenic E. coli, Klebsiella oxytoca, or Klebsiella pneumoniae, can be used to disrupt or prevent the attachment of a single layer of bacteria to a mannose-coated surface, or to disrupt or prevent the formation of a multilayer biofilm. The antibody compositions of the invention can thus be used in methods to inhibit, prevent, or reverse the colonization of a surface with enterobacteria that express the bacterial Type 1 fimbrial adhesin FimH, to inhibit or prevent infection of a cell by enterobacteria that express the bacterial Type 1 fimbrial adhesin FimH, such as, for example, uropathogenic E. coli, to treat a bacterial infection in subject in need thereof and to treat or prevent inflammatory bowel disease (IBD), among other uses.

Abstract: An accessory apparatus includes a housing, an apparatus connector, a plurality of auxiliary accessory interfaces, and an internal microcontroller. The connection connector is configured to mate with a corresponding accessory connector of a physical controller to electrically connect the internal microcontroller to the physical controller. Each auxiliary accessory connector is configured to enable a separate auxiliary user input device to operatively connect to the accessory apparatus and electrically connect with the internal microcontroller. The internal microcontroller is configured to: (1) receive an input control signal from an auxiliary user input device operatively connected to an auxiliary accessory connector of the plurality of auxiliary accessory connectors, (2) map the input control signal to a mapped control signal corresponding to a physical control of the physical controller, and (3) send the mapped control signal to the physical controller via the apparatus connector.