Patents by Inventor Evelyne Chaput

Evelyne Chaput has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrazinecarboxamide derivatives as HDL-cholesterol raising agents
    Patent number: 8188093
    Abstract: The present invention relates to a method of raising HDL cholesterol comprising administering to a patient in need thereof a compound of the formula wherein A, G, R1 to R8 and R17 are as defined in the description.
    Type: Grant
    Filed: June 29, 2010
    Date of Patent: May 29, 2012
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Mirjana Andjelkovic, Agnes Benardeau, Evelyne Chaput, Paul Hebeisen, Matthias Nettekoven, Ulrike Obst Sander, Constantinos G. Panousis, Stephan Roever
  • 3-Pyridinecarboxamide Derivatives as HDL-Cholesterol Raising Agents
    Publication number: 20100267745
    Abstract: The present invention relates to a method of raising HDL cholesterol comprising administering to a patient in need thereof a compound of the formula wherein A, G, R1 to R8 and R17 are as defined in the description.
    Type: Application
    Filed: June 29, 2010
    Publication date: October 21, 2010
    Inventors: Mirjana Andjelkovic, Agnès Bénardeau, Evelyne Chaput, Paul Hebeisen, Matthias Nettekoven, Ulrike Obst Sander, Constantinos G. Panousis, Stephan Roever
  • 3-pyridinecarboxamide derivatives as HDL-cholesterol raising agents
    Patent number: 7812028
    Abstract: The present invention relates to a method of raising HDL cholesterol comprising administering to a patient in need thereof a compound of the formula wherein A, G, R1 to R8 and R17 are as defined in the description.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: October 12, 2010
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Mirjana Andjelkovic, Agnes Benardeau, Evelyne Chaput, Paul Hebeisen, Matthias Nettekoven, Ulrike Obst Sander, Constantinos G. Panousis, Stephan Roever
  • Use of a PPARalpha Agonist and Metformin for Decreasing the Serum Triglycerides
    Publication number: 20100144874
    Abstract: The present invention relates to the combined use of a PPAR? agonist and metformin for decreasing serum triglycerides.
    Type: Application
    Filed: February 12, 2010
    Publication date: June 10, 2010
    Applicant: Fournier Laboratories Ireland Limited
    Inventors: Jean-Louis Junien, Alan Edgar, Evelyne Chaput
  • 3-PYRIDINECARBOXAMIDE DERIVATIVES AS HDL-CHOLESTEROL RAISING AGENTS
    Publication number: 20090143409
    Abstract: The present invention relates to a method of raising HDL cholesterol comprising administering to a patient in need thereof a compound of the formula wherein A, G, R1 to R8 and R17 are as defined in the description.
    Type: Application
    Filed: February 6, 2009
    Publication date: June 4, 2009
    Inventors: Mirjana Andjelkovic, Agnes Benardeau, Evelyne Chaput, Paul Hebeisen, Matthias Nettekoven, Ulrike Obst Sander, Constantinos G. Panousis, Stephan Roever
  • USE OF A PPAR-ALPHA AGONIST TO TREAT PATIENTS SUFFERING FROM WEIGHT GAIN ASSOCIATED WITH A PPAR-GAMMA AGONIST TREATMENT
    Publication number: 20090099238
    Abstract: The present invention relates to the use of a ppar? agonist to treat patients suffering from weight gain associated with a ppar? agonist treatment.
    Type: Application
    Filed: October 10, 2008
    Publication date: April 16, 2009
    Inventors: Jean-Louis Junien, Alan Edgar, Evelyne Chaput
  • 3-Pyridinecarboxamide derivatives as HDL-cholesterol raising agents
    Publication number: 20080085906
    Abstract: The present invention relates to a method of raising HDL cholesterol comprising administering to a patient in need thereof a compound of the formula wherein A, G, R1 to R8 and R17 are as defined in the description.
    Type: Application
    Filed: September 27, 2007
    Publication date: April 10, 2008
    Inventors: Mirjana Andjelkovic, Agnes Benardeau, Evelyne Chaput, Paul Hebeisen, Matthias Nettekoven, Ulrike Sander, Constantinos Panousis, Stephan Roever
  • Use of a pparalpha agonist and metormin for decreasing the serum triglycerides
    Publication number: 20060142397
    Abstract: The present invention relates to the combined use of a PPAR? agonist and metformin for decreasing serum triglycerides.
    Type: Application
    Filed: November 26, 2003
    Publication date: June 29, 2006
    Inventors: Jean-Louis Junien, Alan Edgar, Evelyne Chaput
  • 2-Thiohydantoine derivative compounds and use thereof for the treatment of diabetes
    Publication number: 20060025589
    Abstract: The invention relates to 2-thiohydantoin compounds selected from compounds of general formula (I): in which, in particular, one of the radicals R1 and R2 comprises two aromatic rings in the structure or is the dibenzofuranyl group, R3 is a hydrogen atom, a halogen atom, a C1-C4 alkyl group, a C1-C4 alkoxy group, a hydroxyl group, a phenyl group or a benzyl group, R4 is a hydrogen atom, a halogen atom or a C1-C4 alkyl group, and their addition salts with a non-toxic acid, especially the pharmaceutically acceptable salts. It further relates to the process for their preparation, to the pharmaceutical compositions in which they are present, and to their use as pharmacologically active substances, especially in the case of the treatment of diabetes, diseases due to hyperglycemia, hypertriglyceridemia, dyslipidemia or obesity.
    Type: Application
    Filed: October 3, 2003
    Publication date: February 2, 2006
    Inventors: Jean Binet, Benaissa Boubia, Evelyne Chaput, Alan Edgar, Khan Ou, Philippe Ratel, Soth Samreth, Didier Thomas
  • Thiohydantoins and use thereof for treating diabetes
    Publication number: 20040116417
    Abstract: The invention relates to 2-thiohydantoin derivative compounds selected from compounds of general formula (I): 1
    Type: Application
    Filed: September 26, 2003
    Publication date: June 17, 2004
    Inventors: Benaissa Boubia, Evelyne Chaput, Khan Ou, Philippe Ratel
  • Use of a PPAR-alpha agonist to treat patients suffering from weight gain associated with a PPAR-gamma agonist treatment
    Publication number: 20040110799
    Abstract: The present invention relates to the use of a ppar&agr; agonist to treat patients suffering from weight gain associated with a ppar&ggr; agonist treatment.
    Type: Application
    Filed: August 8, 2003
    Publication date: June 10, 2004
    Inventors: Jean-Louis Junien, Alan Edgar, Evelyne Chaput