Patents by Inventor Evelyne Mathieu

Evelyne Mathieu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of specific relaxation agents for organs or pathologies for modifying the contrasts in medical imaging by nuclear magnetic resonance
    Patent number: 4804529
    Abstract: The invention relates to specific relaxation agents for organs or pathologies, which can be used for modifying the contrasts in medical imaging by nuclear magnetic resonance.These agents are constituted by a complex of a paramagnetic element having a biologically active ligand or a ligand coupled to a biologically active molecule and which is specific to an organ or pathology. Thus, they are selectively fixed to the organs and make it possible to modify the contrasts in imaging by nuclear magnetic resonance, due to the presence of the paramagnetic element, which modifies the relaxation times.For example, when examining the kidney, the complex can be constituted by dimercaptosuccinate or gadolinium diethylene triaminopentaacetate, whilst gadolinium phytate is used in examinations of the liver.
    Type: Grant
    Filed: August 10, 1984
    Date of Patent: February 14, 1989
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Andre Bardy, Maria-Louisa Conti, Jacques Courtieu, Evelyne Mathieu, Joelle Grzyb