Patents by Inventor Everardus Otto Maria Orlemans

Everardus Otto Maria Orlemans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gonadotropin releasing hormone antagonist
    Patent number: 6653286
    Abstract: The present invention relates to a method to prevent a premature LH surge. The method employs the administration of the gonadotropin releasing hormone antagonist ganirelix in an amount between 0.125-1 mg in combination with exogenous FSH. The method can be used in the treatment of women undergoing controlled ovarian superovulation.
    Type: Grant
    Filed: December 20, 1999
    Date of Patent: November 25, 2003
    Assignee: Akzo Nobel NV
    Inventors: Bernadette Maria Julia Louise Mannaerts, Herman Jan Tijmen Coelingh Bennink, Everardus Otto Maria Orlemans
  • Gonadotropin releasing hormone antagonist
    Publication number: 20030092628
    Abstract: The present invention relates to a method to prevent a premature LH surge. The method employs the administration of the gonadotropin releasing hormone antagonist ganirelix in an amount dependent on the body weight of the patient. The method can be used in combination with administration of exogenous FSH in the treatment of women undergoing controlled ovarian super-ovulation.
    Type: Application
    Filed: December 13, 2002
    Publication date: May 15, 2003
    Inventors: Henrik Johan Matthieu Maria de Greef, Bernadette Maria Julia Louise Mannaerts, Everardus Otto Maria Orlemans, Gerrit G. Voortman, Herman Jan Tijmen Coelingh Bennink
  • 17-spiromethylene steroids
    Patent number: 5854235
    Abstract: The invention relates to a steroid derivative which steroidal skeleton is bound at carbon atom 17 to a spiromethylene ring of the formula: ##STR1## wherein R.sub.a and R.sub.b are independently selected from the group consisting of hydrogen, methyl, and halogen; m is 1 or 2; and the asterisk denotes carbon atom 2 of the spiromethylene ring which is carbon atom 17 (or carbon atom 17.alpha. of a homosteroid skeleton) of the steroid. The steroids have progestational or antiprogestational activity.
    Type: Grant
    Filed: November 3, 1997
    Date of Patent: December 29, 1998
    Assignee: Akzo Nobel N.V.
    Inventors: Johannes Antonius Maria Hamersma, Everardus Otto Maria Orlemans, Johannes Bernardus Maria Rewinkel
  • 17-spiromethylene steroids
    Patent number: 5712264
    Abstract: The invention relates to a steroid derivative which steroidal skeleton is bound at carbon atom 17 to a spiromethylene ring of the formula: ##STR1## wherein R.sub.a and R.sub.b are independently selected from the group consisting of hydrogen, methyl, and halogen; m is 1 or 2; and the asterisk denotes carbon atom 2 of the spiromethylene ring which is carbon atom 17 (or carbon atom 17.alpha. of a homosteroid skeleton) of the steroid. The steroids have progestational or antiprogestational activity.
    Type: Grant
    Filed: July 28, 1993
    Date of Patent: January 27, 1998
    Assignee: Akzo Nobel N.V.
    Inventors: Johannes Antonius Maria Hamersma, Everardus Otto Maria Orlemans, Johannes Bernardus Maria Rewinkel