Patents by Inventor Everett M. Schultz

Everett M. Schultz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3,4-Dihydrospiro-2H-1,3-benzoxazines and their use in treating edema, abnormal electrolyte retention, and inflammation
    Patent number: 4092414
    Abstract: 3,4-Dihydrospiro-2H-1,3-benzoxazines are prepared by condensing aminomethylphenols with cyclic ketones. The products are diuretic and anti-inflammatory agents, and are useful in the treatment of autoimmune diseases, such as multiple sclerosis.
    Type: Grant
    Filed: February 19, 1976
    Date of Patent: May 30, 1978
    Assignee: Merck & Co., Inc.
    Inventors: Edward J. Cragoe, Jr., Everett M. Schultz, Gerald E. Stokker
  • Spirobenzoxazinium salts, method of use and compositions thereof as antihypertensive agents
    Patent number: 4067980
    Abstract: Quaternary salts of 3,4-dihydrospiro-2H-1,3-benzoxazines are prepared by treating 3,4-dihydrospiro-2H-1,3-benzoxazines with an alkylating agent. The products are antihypertensive agents.
    Type: Grant
    Filed: August 16, 1976
    Date of Patent: January 10, 1978
    Assignee: Merck & Co., Inc.
    Inventors: Edward J. Cragoe, Jr., Gerald E. Stokker, Everett M. Schultz
  • Antiinflammatory 2-aminomethyl-6-trihalomethylphenols
    Patent number: 4044153
    Abstract: 2-Aminomethylphenol products and their non-toxic, pharmaceutically acceptable salts useful in the treatment of edema and inflammation are disclosed. The products may be prepared by treating an N-(2-hydroxybenzyl)carboxamide with an aqueous solution of an acid or a base.
    Type: Grant
    Filed: May 7, 1976
    Date of Patent: August 23, 1977
    Assignee: Merck & Co., Inc.
    Inventors: Everett M. Schultz, Edward J. Cragoe, Jr.
  • Substituted 2-aminomethyl-6-iodophenols
    Patent number: 4029816
    Abstract: Certain substituted 2-aminomethyl-6-iodophenols and their pharmaceutically acceptable acid addition salts wherein the phenyl nucleus may be further substituted with 1 to 3 nuclear substituents are useful as antihypertensive, diuretic and saluretic agents. These products may be prepared by either iodinating a 2-aminomethyl-3,4,5-substituted phenol or hydrolyzing an appropriately substituted N-(2-hydroxy-3-iodo-4,5,6-substituted benzyl)carboxamide under either acidic or basic conditions.
    Type: Grant
    Filed: September 20, 1976
    Date of Patent: June 14, 1977
    Assignee: Merck & Co., Inc.
    Inventors: Edward J. Cragoe, Jr., Everett M. Schultz
  • (1-Oxo-7,8-disubstituted-1,2,3,4-tetrahydro-6-naphthyloxy)- and (3,4-disubstituted-5-oxo-6,7,8,9-tetrahydro-5H-benzocycloheptene-2-yloxy ) acetic acids and derivatives
    Patent number: 4003927
    Abstract: (1-Oxo-7,8-disubstituted-1,2,3,4-tetrahydro-6-naphthyloxy)- and (3,4-disubstituted-5-oxo-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yloxy)ac etic acids, their carboxylate salts, and the amide and 5-tetrazole derivatives thereof are active as diuretic and saluretic agents, which also have uricosuric activity.
    Type: Grant
    Filed: October 12, 1973
    Date of Patent: January 18, 1977
    Assignee: Merck & Co., Inc.
    Inventors: Otto W. Woltersdorf, Jr., Edward J. Cragoe, Jr., Everett M. Schultz, Gerald E. Stokker
  • 2-Aminomethyl-6-trihalo-methylphenols
    Patent number: 3979361
    Abstract: 2-Aminomethylphenol products and their non-toxic, pharmaceutically acceptable salts useful in the treatment of edema and inflammation are disclosed. The products may be prepared by treating an N-(2-hydroxybenzyl)carboxamide with an aqueous solution of an acid or a base.
    Type: Grant
    Filed: August 1, 1975
    Date of Patent: September 7, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Everett M. Schultz, Edward J. Cragoe, Jr.