Patents by Inventor Evert Njomen

Evert Njomen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STEREOSELECTIVE COVALENT LIGANDS FOR ONCOGENIC AND IMMUNOLOGICAL PROTEINS
    Publication number: 20250034216
    Abstract: Provided are in vivo engineered proteins. The engineered protein may be covalently bound to a ligand.
    Type: Application
    Filed: November 21, 2022
    Publication date: January 30, 2025
    Inventors: Benjamin CRAVATT, Jarrett REMSBERG, Michael LAZEAR, Minoru YOKOYAMA, Michael SCHAFROTH, Daisuke OGASAWARA, Kristen DEMEESTER, Evert NJOMEN, Bruno MELILLO, Stuart SCHREIBER
  • Substituted dibenzo[b, f]azepines as proteasome activators
    Patent number: 12060337
    Abstract: The disclosure is directed to substituted dibenzo[b,f]azepines of the formula (II): wherein the variables n, X3, R1, R2, R4, and R5 are defined herein, and uses of such compounds to treat conditions including neurodegenerative diseases and cancers.
    Type: Grant
    Filed: February 14, 2022
    Date of Patent: August 13, 2024
    Assignee: Board of Trustees of Michigan State University
    Inventors: Jetze J. Tepe, Theresa A. Lansdell, Evert Njomen, Corey Lee Jones
  • SMALL MOLECULE ENHANCEMENT OF 20S PROTEASOME ACTIVITY TARGETS INTRINSICALLY DISORDERED PROTEINS
    Publication number: 20230002335
    Abstract: The disclosure is directed to compounds of the formula (I) and (II) and uses of such compounds to treat, among other conditions, neurodegenerative diseases and cancers.
    Type: Application
    Filed: February 14, 2022
    Publication date: January 5, 2023
    Inventors: Jetze J. Tepe, Theresa A. Lansdell, Evert Njomen, Corey Lee Jones
  • Substituted phenothiazines as proteasome activators
    Patent number: 11358942
    Abstract: The disclosure is directed to compounds of the formula (I): and uses of such compounds to treat neurodegenerative diseases and cancers.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: June 14, 2022
    Assignee: Board of Trustees of Michigan State University
    Inventors: Jetze J. Tepe, Theresa A. Lansdell, Evert Njomen, Corey Lee Jones
  • SMALL MOLECULE PROTEASOME ACTIVATORS AND USES THEREOF
    Publication number: 20200165216
    Abstract: The disclosure is directed to compounds of the formula (I) and (II) and uses of such compounds to treat, among other conditions, neurodegenerative diseases and cancers.
    Type: Application
    Filed: June 4, 2018
    Publication date: May 28, 2020
    Inventors: Jetze J. Tepe, Theresa A. Landsdell, Evert Njomen, Corey Lee Jones