Abstract: An endoscopic sleeve includes a tubular member from which extend spaced projecting elements. The projecting elements are bendable towards both proximal and distal directions of the tubular member. The force (insertion force) required to bend the projecting elements towards the proximal direction is less than a force (extraction force) required to bend the projecting elements towards the distal direction. An outer periphery of the projecting elements decreases as the extraction force increases.

Abstract: In-vivo devices, systems and methods for the detection of blood within in-vivo bodily fluids. The methods include irradiating in-vivo fluids passing through a gap in a housing of an in-vivo device introduced to the GI tract of a subject with a plurality of illumination sources positioned on a first side of a gap; detecting with at least one light detector positioned on the opposite side of the gap and facing the illumination sources, light irradiated by the illumination sources; transmitting a plurality of values representing the light detected over time; converting these values to blood concentration values over time, and comparing the blood concentration values to a predetermined threshold value. Based on the comparison, the method includes determining the type of bleeding profile, such that if a plurality of blood concentration values measured consecutively is above the threshold value, the bleeding profile indicates bleeding.