Patents by Inventor Evgueni Kvassiouk

Evgueni Kvassiouk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of manufacturing labelled oligonucleotide conjugates
    Patent number: 7687618
    Abstract: The present invention relates to a method for the manufacture of labeled oligonucleotide conjugates comprising the reaction of (a) an oligonucleotide having a labile protecting group bound to a terminal hydroxy group, and (b) a labeling compound, wherein said labile protecting group is partially or completely substituted by said labeling compound in a nucleophilic substitution reaction.
    Type: Grant
    Filed: October 14, 2003
    Date of Patent: March 30, 2010
    Assignee: NIMBLEGEN SYSTEMS GmbH
    Inventors: Klaus Peter Stengele, Evgueni Kvassiouk
  • Method for covalently attaching nucleosides and/or nucleotides on surfaces and method for determining coupling yields in the synthesis of nucleotides
    Publication number: 20060154256
    Abstract: The present invention relates to a method for covalently attaching nucleosides and/or nucleotides on surfaces having reactive functional groups, where in a first step, the reactive functional groups are made to react with suitable derivatized nucleosides and/or nucleotides, and in a second step, they are converted with a protecting group reagent, so that a reaction product of the consecutive reaction interacts with electromagnetic radiation such that it can be quantitatively determined.
    Type: Application
    Filed: April 23, 2004
    Publication date: July 13, 2006
    Inventors: Klaus-Peter Stengele, Evgueni Kvassiouk
  • Method of manufacturing labelled oligonucleotide conjugates
    Publication number: 20060122382
    Abstract: The present invention relates to a method for the manufacture of labeled oligonucleotide conjugates comprising the reaction of (a) an oligonucleotide having a labile protecting group bound to a terminal hydroxy group, and (b) a labeling compound, wherein said labile protecting group is partially or completely substituted by said labeling compound in a nucleophilic substitution reaction.
    Type: Application
    Filed: October 14, 2003
    Publication date: June 8, 2006
    Inventors: Klaus Stengele, Evgueni Kvassiouk