Abstract: Prosthesis deployment devices and methods of a deploying a prosthesis are disclosed herein. In some embodiments, a prosthesis deployment device includes an elongate delivery catheter assembly and a housing assembly. The elongate delivery catheter assembly is configured for electrosurgery and also configured to retain and deploy a prosthesis from a distal region of the delivery catheter assembly. The distal region of the delivery catheter assembly includes a tip electrode and a distal marker configured to provide endoscopic visibility of the distal region during use and spaced from the tip electrode. The housing assembly operably coupled to the delivery catheter assembly and configured to connect to an electrosurgical power generator. The housing assembly comprises an actuator configured to displace a portion of the delivery catheter assembly to deploy the prosthesis, upon actuation.

Abstract: Prosthesis deployment devices and methods of a deploying a prosthesis are disclosed herein. In some embodiments, a method of deploying a prosthesis includes advancing a tip of a delivery catheter assembly positioned at a distal region of the delivery catheter assembly into one or more target structures, aligning an alignment indicator in the distal region of the delivery catheter assembly with a proximal surface of a proximal target structure of the one or more target structures, after the alignment indicator is aligned with the proximal surface of the proximal target structure actuating an actuator of a housing assembly operably connected to the delivery catheter assembly and thereby deploying a distal end of the prosthesis in the patient, and actuating the actuator of the housing assembly and thereby deploying a proximal end of the prosthesis in the patient.

Abstract: The present disclosure is directed to a device for screening pre-filled syringes configured to determine whether a stopper position within each syringe falls within an acceptable tolerance prior to final assembly of a syringe into a corresponding autoinjector device, thereby ensuring proper fit of the syringe within the autoinjector device and further ensuring accurate delivery of a desired dose of fluid from the syringe during operation of the autoinjector.

Abstract: Transluminal stents are disclosed herein. In some embodiments stents within the scope of this disclosure may comprise a first flared end, second flared end, and a middle region disposed between the first and second flared ends. The middle region may comprise a concave, curvilinear shape. The middle region may include a first portion, a second portion, and a circumferential ridge disposed between the first and second portions. The first flared end may include a first inner shoulder extending between the middle region and a first crest, a first opening, and a first outer taper extending between the first crest and the first opening. Methods of using the transluminal stents are also disclosed herein.

Abstract: Plunger rod stops attach to existing syringes to limit the range of motion of the plunger, thereby to precisely control the amount of liquid that can be expelled from the syringe when the plunger rod stop is in place. In some embodiments, plunger rod stop devices generally include a body configured to attach to the plunger, and a stand-off extending from the body, configured to contact the finger flange when the plunger is depressed. In other embodiments, the plunger rod stop attaches to the finger flange or other fixed component of the syringe and the stand-off is configured to contact the plunger or plunger rod. Methods of the invention involve using the devices to interfere with the range of motion of the plunger, then reconfiguring or removing the device to allow the plunger to be moved a predetermined length, which corresponds to a precise dosage amount.

Abstract: The present disclosure is directed to a device for screening pre-filled syringes configured to determine whether a stopper position within each syringe falls within an acceptable tolerance prior to final assembly of a syringe into a corresponding autoinjector device, thereby ensuring proper fit of the syringe within the autoinjector device and further ensuring accurate delivery of a desired dose of fluid from the syringe during operation of the autoinjector.

Abstract: The present disclosure is directed to a device for screening pre-filled syringes configured to determine whether a stopper position within each syringe falls within an acceptable tolerance prior to final assembly of a syringe into a corresponding autoinjector device, thereby ensuring proper fit of the syringe within the autoinjector device and further ensuring accurate delivery of a desired dose of fluid from the syringe during operation of the autoinjector.

Abstract: Plunger rod stops attach to existing syringes to limit the range of motion of the plunger, thereby to precisely control the amount of liquid that can be expelled from the syringe when the plunger rod stop is in place. In some embodiments, plunger rod stop devices generally include a body configured to attach to the plunger, and a stand-off extending from the body, configured to contact the finger flange when the plunger is depressed. In other embodiments, the plunger rod stop attaches to the finger flange or other fixed component of the syringe and the stand-off is configured to contact the plunger or plunger rod. Methods of the invention involve using the devices to interfere with the range of motion of the plunger, then reconfiguring or removing the device to allow the plunger to be moved a predetermined length, which corresponds to a precise dosage amount.

Abstract: Plunger rod stops attach to existing syringes to limit the range of motion of the plunger, thereby to precisely control the amount of liquid that can be expelled from the syringe when the plunger rod stop is in place. In some embodiments, plunger rod stop devices generally include a body configured to attach to the plunger, and a stand-off extending from the body, configured to contact the finger flange when the plunger is depressed. In other embodiments, the plunger rod stop attaches to the finger flange or other fixed component of the syringe and the stand-off is configured to contact the plunger or plunger rod. Methods of the invention involve using the devices to interfere with the range of motion of the plunger, then reconfiguring or removing the device to allow the plunger to be moved a predetermined length, which corresponds to a precise dosage amount.

Abstract: The present disclosure is directed to a device for screening pre-filled syringes configured to determine whether a stopper position within each syringe falls within an acceptable tolerance prior to final assembly of a syringe into a corresponding autoinjector device, thereby ensuring proper fit of the syringe within the autoinjector device and further ensuring accurate delivery of a desired dose of fluid from the syringe during operation of the autoinjector.

Abstract: Plunger rod stops attach to existing syringes to limit the range of motion of the plunger, thereby to precisely control the amount of liquid that can be expelled from the syringe when the plunger rod stop is in place. In some embodiments, plunger rod stop devices generally include a body configured to attach to the plunger, and a stand-off extending from the body, configured to contact the finger flange when the plunger is depressed. In other embodiments, the plunger rod stop attaches to the finger flange or other fixed component of the syringe and the stand-off is configured to contact the plunger or plunger rod. Methods of the invention involve using the devices to interfere with the range of motion of the plunger, then reconfiguring or removing the device to allow the plunger to be moved a predetermined length, which corresponds to a precise dosage amount.