Abstract: A biocompatible and biodegradable medical device patch actuating primarily as soft tissue structural reinforcement. The device has a layered architecture, where the primary serves as suturing layer and mechanical support to a thick porous scaffold which can be coated with a mimic-like extra cellular matrix (ECM). The device can be provided to the end user under the format of independent layers that can be cut and assembled to the specific need to the end user and patient. The layers are assembled without the need of any adhesive. Totally haemocompatible and of behavior superior to polytetrafluoroethylene used for any soft tissue repaired, the field of this invention is demonstrated for cardiovascular therapy but should not be limited to it. It is of practical relevance of vein, tendon and hernias and dermal treatments.

Abstract: A biocompatible and biodegradable medical device patch actuating primarily as soft tissue structural reinforcement. The device has a layered architecture, where the primary serves as suturing layer and mechanical support to a thick porous scaffold which can be coated with a mimic-like extra cellular matrix (ECM). The device can be provided to the end user under the format of independent layers that can be cut and assembled to the specific need to the end user and patient. The layers are assembled without the need of any adhesive. Totally haemocompatible and of behavior superior to polytetrafluoroethylene used for any soft tissue repaired, the field of this invention is demonstrated for cardiovascular therapy but should not be limited to it. It is of practical relevance of vein, tendon and hernias and dermal treatments.

Abstract: The invention relates to a method for production of polymeric nanofibers, in which polymeric nanofibers are created due to the action of force of an electric field on solution or melt of a polymer, which is located on the surface of a spinning electrode, whereby the electric field for electrostatic spinning is created alternately between the spinning electrode (1), to which is supplied alternating voltage, and ions (30, 31) of air and/or gas generated and/or supplied to proximity of the spinning electrode (1), whereby according to the phase of the alternating voltage on the spinning electrode (1) polymeric nanofibers with an electric charge of opposite polarity and/or with segments with an electric charge of opposite polarity are created, which after their creation cluster together under the influence of the electrostatic forces into linear formation in the form of a tow or a band, which moves freely in space in direction of gradient of the electric fields away from the spinning electrode (1).

Abstract: The invention relates to a method for production of polymeric nanofibers, in which polymeric nanofibers are created due to the action of force of an electric field on solution or melt of a polymer, which is located on the surface of a spinning electrode, whereby the electric field for electrostatic spinning is created alternately between the spinning electrode (1), to which is supplied alternating voltage, and ions (30, 31) of air and/or gas generated and/or supplied to proximity of the spinning electrode (1), whereby according to the phase of the alternating voltage on the spinning electrode (1) polymeric nanofibers with an electric charge of opposite polarity and/or with segments with an electric charge of opposite polarity are created, which after their creation cluster together under the influence of the electrostatic forces into linear formation in the form of a tow or a band, which moves freely in space in direction of gradient of the electric fields away from the spinning electrode (1).

Abstract: A biocompatible and biodegradable medical device patch actuating primarily as soft tissue structural reinforcement. The device has a layered architecture, where the primary serves as suturing layer and mechanical support to a thick porous scaffold which can be coated with a mimic-like extra cellular matrix (ECM). The device can be provided to the end user under the format of independent layers that can be cut and assembled to the specific need to the end user and patient. The layers are assembled without the need of any adhesive. Totally haemocompatible and of behavior superior to polytetrafluoroethylene used for any soft tissue repaired, the field of this invention is demonstrated for cardiovascular therapy but should not be limited to it. It is of practical relevance of vein, tendon and hernias and dermal treatments.