Abstract: An OCT apparatus for acquiring optoretinography data, comprising: an optical system which applies an optical stimulus confined to a portion of a retina of the eye whose location is controllable; an OCT imaging system which acquires OCT data from the retina; and a controller which: acquires a duration of a physiological response of the retina in the optoretinography data to be acquired; acquires target locations on the retina and uses these to control the optical system to apply the optical stimulus to respective first portions of the retina at the respective target locations; controls the OCT imaging system to acquire, for each first portion, respective OCT data of the respective second portion of the retina over the duration indicated by the first indicator, which second portion is stimulated by the optical stimulus applied to the first portion; and generates the ORG data based on the acquired OCT data.

Abstract: A computer-implemented method of processing respective phase components of a first OCT image and a second OCT image of a sequence of OCT images of a common portion of a retina acquired by a Fourier-domain OCT imaging system after stimulation of the common portion by an optical stimulus, the common portion comprising a layer of the retina whose thickness changed during acquisition of the sequence of OCT images, to determine an indication of a position along an axial direction in the OCT images of a boundary of the layer, the method comprising: processing the phase component of the first OCT image and the phase component of the second OCT image to calculate a velocity profile indicative of a distribution, along the axial direction, of velocity within the common portion of the retina; and determining the indication based on the calculated velocity profile.

Abstract: A computer-implemented method of processing each of a plurality of sets of OCT images in a sequence of OCT images of a portion of a retina to generate a respective indication of a tissue velocity at a position along an axial direction in the OCT images, by performing, for each set: calculating a respective comparison value based on an image quality or similarity of a first OCT image and a second OCT image in the set; using phase information in the first OCT and second OCT image in a calculation of the respective indication of tissue velocity at the position if the comparison value is equal to or greater than a threshold; and omitting the phase information from the calculation if the comparison value is smaller than the threshold.

Abstract: A Fourier-domain OCT apparatus for optoretinography is provided. An example Fourier-domain OCT apparatus comprises: a fixation target which fixes a gaze direction of an eye; an optical system which applies an optical stimulus which is confined to a portion of a retina of the eye whose location is controllable; an OCT imaging system which acquires OCT data from the retina; and a controller which: acquires a target location on the retina; uses the target location to control the optical system, while a position of the fixation target relative to the eye remains fixed, to apply the optical stimulus to a first portion of the retina at the target location; controls the OCT imaging system to acquire OCT data of a second portion of the retina which is stimulated by the applied optical stimulus during acquisition of the OCT data; and generates the ORG data based on the acquired OCT data.

Abstract: A Fourier-domain OCT apparatus for acquiring optoretinography data, comprising: an optical system which applies an optical stimulus to a retina of an eye; an OCT imaging system which acquires OCT data from the retina; and a controller which: controls the OCT imaging system to acquire OCT data of a plurality of portions of the retina such that, for each portion, at least some of the OCT data from the portion is acquired after a respective optical stimulus has been applied to the portion; generates, based on the OCT data, respective ORG data for each portion which indicates the response of the portion to the optical stimulus; and stores respective ORG data generated for each portion in association with a respective position in a visual field of the eye that is optically conjugate with a position of the portion on the retina.

Abstract: A Fourier-domain optical coherence tomography imaging system (10) comprising an Fourier-domain optical coherence tomography scanner (20) arranged to generate complex optical coherence tomography data (25) by performing a scan of an imaging target (30) to acquire samples whose complex values are indicative of an optical property of the imaging target at respective scan locations in the imaging target. The imaging system (10) further comprises a controller (40) arranged to calculate a two-dimensional cross-correlation using phase information of the acquired samples, and control the scanner (20), based on the calculated cross-correlation, to compensate for relative movement between the imaging target (30) and the scanner (20) during the scan.