Patents by Inventor Ewy A. Mathe

Ewy A. Mathe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the diagnosis and prognosis of cancer
    Patent number: 11555818
    Abstract: The present invention provides methods and materials for diagnosing cancer in an individual using a tissue, blood or urine sample from the patient. Specifically, the disclosed method comprises determining the level of one or more metabolite selected from the group consisting of creatine riboside, metabolite 561+, cortisol sulfate and N-acetylneuraminic acid. The present invention also provides a method for determining the prognosis of a cancer patient by determining the level of one or more metabolite selected from the group consisting of creatine riboside, metabolite 561+, cortisol sulfate and N-acetylneuraminic acid. Also provided are kits for detecting cancer or determining the prognosis of a cancer patient.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: January 17, 2023
    Assignee: The USA, as represted by the Secretary, Dept. of and Human Services, National Institutes of Health
    Inventors: Majda Haznadar, Ewy Mathe, Andrew D. Patterson, Curtis Craig Harris, Frank Gonzalez, Kristopher Krausz, Soumen Manna
  • METHOD FOR THE DIAGNOSIS AND PROGNOSIS OF CANCER
    Publication number: 20190369102
    Abstract: The present invention provides methods and materials for diagnosing cancer in an individual using a tissue, blood or urine sample from the patient. Specifically, the disclosed method comprises determining the level of one or more metabolite selected from the group consisting of creatine riboside, metabolite 561+, cortisol sulfate and N-acetylneuraminic acid. The present invention also provides a method for determining the prognosis of a cancer patient by determining the level of one or more metabolite selected from the group consisting of creatine riboside, metabolite 561+, cortisol sulfate and N-acetylneuraminic acid. Also provided are kits for detecting cancer or determining the prognosis of a cancer patient.
    Type: Application
    Filed: May 14, 2019
    Publication date: December 5, 2019
    Inventors: Majda HAZNADAR, Ewy MATHE, Andrew D. PATTERSON, Curtis Craig HARRIS, Frank GONZALEZ, Kristopher KRAUSZ, Soumen MANNA
  • Method for the diagnosis and prognosis of cancer
    Patent number: 10393745
    Abstract: The present invention provides methods and materials for diagnosing cancer in an individual using a tissue, blood or urine sample from the patient. Specifically, the disclosed method comprises determining the level of one or more metabolite selected from the group consisting of creatine riboside, metabolite 561+, Cortisol sulfate and N-acetylneuraminic acid. The present invention also provides a method for determining the prognosis of a cancer patient by determining the level of one or more metabolite selected from the group consisting of creatine riboside, metabolite 561+, Cortisol sulfate and N-acetylneuraminic acid. Also provided are kits for detecting cancer or determining the prognosis of a cancer patient.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: August 27, 2019
    Assignee: The USA, as represented by the Secretary, Department of Heath and Human Services
    Inventors: Majda Haznadar, Ewy Mathe, Andrew D. Patterson, Curtis Craig Harris, Frank Gonzalez, Kristopher Krausz, Soumen Manna
  • METHOD FOR THE DIAGNOSIS AND PROGNOSIS OF CANCER
    Publication number: 20160169899
    Abstract: The present invention provides methods and materials for diagnosing cancer in an individual using a tissue, blood or urine sample from the patient. Specifically, the disclosed method comprises determining the level of one or more metabolite selected from the group consisting of creatine riboside, metabolite 561+, Cortisol sulfate and N-acetylneuraminic acid. The present invention also provides a method for determining the prognosis of a cancer patient by determining the level of one or more metabolite selected from the group consisting of creatine riboside, metabolite 561+, Cortisol sulfate and N-acetylneuraminic acid. Also provided are kits for detecting cancer or determining the prognosis of a cancer patient.
    Type: Application
    Filed: July 11, 2014
    Publication date: June 16, 2016
    Inventors: Majda HAZNADAR, Ewy MATHE, Andrew D. PATTERSON, Curtis Craig HARRIS, Frank GONZALEZ, Kristopher KRAUSZ, Soumen MANN
  • Methods and Compositions for the Diagnosis and Treatment of Esphageal Adenocarcinomas
    Publication number: 20100285471
    Abstract: Methods and compositions for the diagnosis, prognosis and/or treatment of esophageal adenocarcinoma and Barrett's esophagus associated adenocarcinoma are disclosed, along with more markers where a difference is indicative of esophageal adenocarcinoma and squamous cell carcinoma, and/or Barrett's esophagus associated adenocarcinomas or a predisposition thereto. The invention also provides methods and compositions of identifying anti-cancer agents therefor.
    Type: Application
    Filed: October 10, 2008
    Publication date: November 11, 2010
    Applicants: THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION, The Government of the US of America as represented by any Secretary of the Dept. of Health
    Inventors: Carlo M. Croce, Curtis C. Harris, Ewy A. Mathe