Patents by Inventor Eyal Gruebaum

Eyal Gruebaum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of modulation of the immune system
    Patent number: 7205113
    Abstract: Manipulation of the EphB6 receptor and its active Eph partners allow for regulation of T cell responses, including TCR signaling, T cell proliferation, and induction of T cell death. Methods of modulating EphB6 are described as well as various therapeutic applications.
    Type: Grant
    Filed: January 5, 2001
    Date of Patent: April 17, 2007
    Assignee: The Hospital for Sick Children
    Inventors: Chaim M. Roifman, Andrew Freywald, Nigel Sharfe, Thomas Grunberger, Eyal Gruebaum
  • Methods of modulation of the immune system
    Publication number: 20030113328
    Abstract: Manipulation of the EphB6 receptor and its active Eph partners allow for regulation of T cell responses, including TCR signalling, T cell proliferation, and induction of T cell death. Methods of modulating EphB6 are described as well as various therapeutic applications.
    Type: Application
    Filed: October 26, 2002
    Publication date: June 19, 2003
    Inventors: Chaim M Roifman, Andrew Freywald, Nigel Sharfe, Thomas Grunberger, Eyal Gruebaum