Patents by Inventor Eytan Domany

Eytan Domany has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11846636
    Abstract: Methods and kits for diagnosing systemic lupus erythematosus (SLE) in a subject are provided. Particularly, the present invention relates to specific oligonucleotide antibody reactivities useful in diagnosing SLE in a subject.
    Type: Grant
    Filed: January 24, 2020
    Date of Patent: December 19, 2023
    Assignee: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Irun R. Cohen, Eytan Domany, Noam Shental, Ittai Fattal
  • Patent number: 11002735
    Abstract: Method, system and an article of manufacture for clustering and thereby identifying predefined antigens reactive with undetermined immunoglobulins of sera derived from patient subjects in need of diagnosis of disease or monitoring of treatment.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: May 11, 2021
    Assignee: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Irun R. Cohen, Eytan Domany, Francisco Javier Quintana, Guy Hed, Gad Getz
  • Publication number: 20200264172
    Abstract: Methods and kits for diagnosing systemic lupus erythematosus (SLE) in a subject are provided. Particularly, the present invention relates to specific oligonucleotide antibody reactivities useful in diagnosing SLE in a subject.
    Type: Application
    Filed: January 24, 2020
    Publication date: August 20, 2020
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Irun R. COHEN, Eytan DOMANY, Noam SHENTAL, Ittai FATTAL
  • Publication number: 20200225223
    Abstract: Method, system and an article of manufacture for clustering and thereby identifying predefined antigens reactive with undetermined immunoglobulins of sera derived from patient subjects in need of diagnosis of disease or monitoring of treatment.
    Type: Application
    Filed: January 21, 2020
    Publication date: July 16, 2020
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Irun R. COHEN, Eytan DOMANY, Francisco Javier QUINTANA, Guy HED, Gad GETZ
  • Patent number: 10545144
    Abstract: Methods and kits for diagnosing systemic lupus erythematosus (SLE) in a subject are provided. Particularly, the present invention relates to specific oligonucleotide antibody reactivities useful in diagnosing SLE in a subject.
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: January 28, 2020
    Assignee: YEDA RESEARCH AND DEVELOPMENT CO., LTD.
    Inventors: Irun R. Cohen, Eytan Domany, Noam Shental, Ittai Fattal
  • Publication number: 20190004045
    Abstract: Method, system and an article of manufacture for clustering and thereby identifying predefined antigens reactive with undetermined immunoglobulins of sera derived from patient subjects in need of diagnosis of disease or monitoring of treatment.
    Type: Application
    Filed: September 6, 2018
    Publication date: January 3, 2019
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Irun R. COHEN, Eytan DOMANY, Francisco Javier QUINTANA, Guy HED, Gad GETZ
  • Patent number: 10082503
    Abstract: Method, system and an article of manufacture for clustering and thereby identifying predefined antigens reactive with undetermined immunoglobulins of sera derived from patient subjects in need of diagnosis of disease or monitoring of treatment.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: September 25, 2018
    Assignee: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Irun R. Cohen, Eytan Domany, Francisco Javier Quintana, Guy Hed, Gad Getz
  • Publication number: 20170016895
    Abstract: Methods and kits for diagnosing systemic lupus erythematosus (SLE) in a subject are provided. Particularly, the present invention relates to specific oligonucleotide antibody reactivities useful in diagnosing SLE in a subject.
    Type: Application
    Filed: December 31, 2014
    Publication date: January 19, 2017
    Inventors: Irun R. Cohen, Eytan Domany, Noam Shental, Ittai Fattal
  • Publication number: 20160320384
    Abstract: A method of assaying or monitoring the determining immunological competence of a subject, particularly for determining immunological competence in a subject, including but not limited to a transplant recipient, is provided. The method comprises measuring the levels of antibodies in a sample obtained from a subject to poly-guanine oligonucleotides.
    Type: Application
    Filed: December 31, 2014
    Publication date: November 3, 2016
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Irun R. Cohen, Eytan Domany, Noam Shental, Ittai Fattal
  • Publication number: 20160069896
    Abstract: Methods and kits for diagnosing systemic lupus erythematosus (SLE) or scleroderma in a subject are provided. Particularly, the present invention relates to a specific antibody reactivity profile useful in diagnosing SLE or scleroderma in a subject.
    Type: Application
    Filed: December 16, 2013
    Publication date: March 10, 2016
    Applicant: Yeda Research and Development Co., Ltd.
    Inventors: Irun R. COHEN, Eytan DOMANY, Ittai FATTAL, Noam SHENTAL
  • Patent number: 9075072
    Abstract: A method of recognizing the development of an Acute Myocardial Infarction (AMI) process in an individual, wherein the method comprises steps of: profiling specific antibody reactivities or biomarkers associated with AMI susceptibility, the profiling comprises steps of: attaching a set of defined antigens to a substrate; obtaining a biological fluid derived specimen from an individual, the specimen containing a specific antibody repertoire; and binding said antibodies of the biological fluid specimen to the attached antigens thereby forming bound antibody antigen complexes; and analyzing results obtained, wherein the presence of the complexes is indicative of AMI.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: July 7, 2015
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Irun R. Cohen, Eytan Domany, Eli Sahar, Noam Shental
  • Publication number: 20140342939
    Abstract: The present invention relates to methods and kits for diagnosing systemic lupus erythematosus (SLE) in a subject. Particularly, the present invention relates to a specific antibody profile useful in diagnosing SLE in a subject.
    Type: Application
    Filed: July 31, 2014
    Publication date: November 20, 2014
    Inventors: Irun R. Cohen, Eytan Domany, Noam Shental, Ittai Fattal
  • Publication number: 20140336077
    Abstract: A method of recognizing the development of an Acute Myocardial Infarction (AMI) process in an individual, wherein the method comprises steps of: profiling specific antibody reactivities or biomarkers associated with AMI susceptibility, the profiling comprises steps of: attaching a set of defined antigens to a substrate; obtaining a biological fluid derived specimen from an individual, the specimen containing a specific antibody repertoire; and binding said antibodies of the biological fluid specimen to the attached antigens thereby forming bound antibody antigen complexes; and analyzing results obtained, wherein the presence of the complexes is indicative of AMI.
    Type: Application
    Filed: July 29, 2014
    Publication date: November 13, 2014
    Inventors: Irun R. Cohen, Eytan Domany, Eli Sahar, Noam Shental
  • Publication number: 20140315740
    Abstract: A method of diagnosing an immune disease, or a predisposition thereto, in a subject is disclosed.
    Type: Application
    Filed: June 30, 2014
    Publication date: October 23, 2014
    Inventors: Irun R. Cohen, Francisco Javier Quintana, Eytan Domany, Gad Elizur, Peter H. Hagedorn
  • Publication number: 20140229116
    Abstract: A system and method for non-linear quantification of pathway deregulation in an individual biological sample for analysis of malignancies.
    Type: Application
    Filed: February 14, 2014
    Publication date: August 14, 2014
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Eytan DOMANY, Michal SHEFFER, Shlomo URBACH, Yotam DRIER
  • Publication number: 20140200159
    Abstract: Method, system and an article of manufacture for clustering and thereby identifying predefined antigens reactive with undetermined immunoglobulins of sera derived from patient subjects in need of diagnosis of disease or monitoring of treatment.
    Type: Application
    Filed: March 13, 2014
    Publication date: July 17, 2014
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Irun R. Cohen, Eytan Domany, Francisco Javier Quintana, Guy Hed, Gad Getz
  • Patent number: 8703654
    Abstract: Method, system and an article of manufacture for clustering and thereby identifying predefined antigens reactive with undetermined immunoglobulins of sera derived from patient subjects in need of diagnosis of disease or monitoring of treatment.
    Type: Grant
    Filed: August 11, 2011
    Date of Patent: April 22, 2014
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Irun R. Cohen, Eytan Domany, Francisco Javier Quintana, Guy Hed, Gad Getz
  • Publication number: 20130252839
    Abstract: The present invention relates to methods for diagnosing transplant rejection, or a condition associated with transplant rejection, such as, primary graft dysfunction in a subject, to antigen probe arrays for performing such a diagnosis, and to antigen probe sets for generating such arrays.
    Type: Application
    Filed: October 11, 2011
    Publication date: September 26, 2013
    Inventors: Sahar Elhanan, Eytan Domany, Irun R. Cohen, Peter Hagedorn, Christopher Malcolm Burton, Henrik Flyvbjerg, Martin P. Iversen
  • Publication number: 20130035254
    Abstract: The present invention relates to methods and kits for diagnosing systemic lupus erythematosus (SLE) in a subject. Particularly, the present invention relates to a specific antibody profile useful in diagnosing SLE in a subject.
    Type: Application
    Filed: February 13, 2011
    Publication date: February 7, 2013
    Inventors: Irun R. Cohen, Eytan Domany, Noam Shental, Ittai Fattal
  • Publication number: 20120122720
    Abstract: A method of recognizing the development of an Acute Myocardial Infarction (AMI) process in an individual, wherein the method comprises steps of: profiling specific antibody reactivities or biomarkers associated with AMI susceptibility, the profiling comprises steps of: attaching a set of defined antigens to a substrate; obtaining a biological fluid derived specimen from an individual, the specimen containing a specific antibody repertoire; and binding said antibodies of the biological fluid specimen to the attached antigens thereby forming bound antibody antigen complexes; and analyzing results obtained, wherein the presence of the complexes is indicative of AMI.
    Type: Application
    Filed: May 5, 2010
    Publication date: May 17, 2012
    Applicant: YEDA RESEARCH & DEVELOPMENT CO. LTD.
    Inventors: Irun R. Cohen, Eytan Domany, Eli Sahar, Noam Shental