Patents by Inventor Eytan Klausner

Eytan Klausner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gastroretentive controlled release pharmaceutical dosage forms
    Patent number: 6685962
    Abstract: Pharmaceutical gastroretentive drug delivery systems for the controlled release of an active agent in the gastrointestinal tract are disclosed, which comprise: (a) a single- or multi-layered matrix comprising a polymer that does not retain in the stomach more than a conventional dosage form selected from (1) degradable polymers that may be hydrophilic polymers not instantly soluble in gastric fluids, enteric polymers substantially insoluble at pH less than 5.5 and/or hydrophobic polymers and mixtures thereof; (2) non-degradable polymers; and any mixtures of (1) and (2); (b) a continuous or non-continuous membrane comprising at least one polymer having a substantial mechanical strength; and (c) a drug; wherein the matrix when affixed or attached to the membrane prevents evacuation from the stomach of the delivery system for a period of time of from about 3 to about 24 hours.
    Type: Grant
    Filed: May 29, 2002
    Date of Patent: February 3, 2004
    Assignee: Yissum Research Development Company Of The Hebrew University Of Jerusalem
    Inventors: Michael Friedman, Eytan Klausner, Eran Lavy, Amnon Hoffman
  • Gastroretentive controlled release pharmaceutical dosage forms
    Publication number: 20030021845
    Abstract: Pharmaceutical gastroretentive drug delivery systems for the controlled release of an active agent in the gastrointestinal tract are disclosed, which comprise: (a) a single- or multi-layered matrix comprising a polymer that does not retain in the stomach more than a conventional dosage form selected from (1) degradable polymers that may be hydrophilic polymers not instantly soluble in gastric fluids, enteric polymers substantially insoluble at pH less than 5.5 and/or hydrophobic polymers and mixtures thereof; (2) non-degradable polymers; and any mixtures of (1) and (2); (b) a continuous or non-continuous membrane comprising at least one polymer having a substantial mechanical strength; and (c) a drug; wherein the matrix when affixed or attached to the membrane prevents evacuation from the stomach of the delivery system for a period of time of from about 3 to about 24 hours.
    Type: Application
    Filed: May 29, 2002
    Publication date: January 30, 2003
    Applicant: Yissum Research Development Company of the Hebrew University Of Jerusalem
    Inventors: Michael Friedman, Eytan Klausner, Eran Lavy, Amnon Hoffman